Andrew Kennard @askennard@qoto.org

James Kitchens' post on "Why Are There So Many Gene Trees?" Illustrating why genomes contain many different genealogical histories.
https://james-kitchens.com/blog/why-are-there-so-many-gene-trees

I thought this paper by Pacheco et al. was interesting, showing how mobile PI(4,5)P2 is on the plasma membrane. Surprisingly PIP2 is highly mobile even when engaged with e.g. clathrin machinery. Nice use of SPT/TrackMate and reporters to examine lipid distribution in the membrane.

https://rupress.org/jcb/article/222/2/e202204099/213711/PI-4-5-P2-diffuses-freely-in-the-plasma-membrane

Note: I'll try to boost interesting #cellbiology papers occasionally. Join me! Maybe we can use the #paperotd paper of the day hashtag of yesteryear.

If things had started out just a *little* differently, people might have actually learned the correct meaning of "chaos."

🚨JOB ALERT🚨
Our awesome team at Human Technopole in Milan, is hiring a Bioimage Analyst! You can find the job posting below. Applications close December 16th. Come and join us!

https://careers.humantechnopole.it/o/bioimage-analyst-and-research-software-engineer-computational-biology-research-center

I guess I should introduce myself #onhere: I am a postdoc in the Schier Lab at the Biozentrum (Switzerland). I am using #zebrafish to understand the #development of the nervous system. I love developmental biology of classic and non-canonical organisms, microscopy, loud music and comic books. Very much looking forward to meeting other scientists and cool people!
PS: I also help co-managing @ZebrafishRock , so make sure to give them a follow for the latest zebrafish community news

It's been years in the making (literally, my PR was ~ two years old 😅 ), but I finally updated Crispulator.jl to work with #julialang 1.0+.

It's ready to help you simulate your pooled #CRISPR screens for #functionalgenomics so that you can make sure they'll work before you pour many months into them!

Check out the refreshed docs: https://tamasnagy.com/Crispulator.jl/dev/

Almost that time of the year again. Who´s going to #CellBio2022?

I'm excited to share that our team has a new opening for a Computational Biologist role at Invitae.

We are a highly cross-functional research team of computational, experimental and clinical scientists with a mandate to maximize the utility of genomic information by developing and validating new insights into the effect of genetic variants.

https://boards.greenhouse.io/invitae/jobs/4710235

#hiring #genomics

Beautiful #cryoET paper on choanoflagellate #flagella #cilia revealing the enigmatic ciliary vane, new components and similarities to animal cilia
#protist #evolution #EM #choanoflagellate
https://elifesciences.org/articles/78133

is it surprising that nucleotide analogs are good cancer drugs, but not (to my knowledge) ribosomal poisons or anti-protein synthesis drugs?

The NIH Advisory Committee to the Director is starting a working group on “Re-envisioning NIH-supported Postdoctoral Training.” Slide deck here has some data and details: https://acd.od.nih.gov/documents/presentations/11032022_ACD_Working_Group_Postdoc.pdf

What would you like them to know? What would you like them to do?

#Introduction: I am curious about how proteins and membranes work in cells to deliver cargos. Multidisciplinary lab (with great collaborators) at UMass Chan Medical School #MembraneTraffic #Biochemistry #StructuralBiology #CryoEM #Biophysics #CellBiology #Genetics #Immunology
Also passionate to increase diversity, equity, inclusion and belonging in #Science #Academia.

Way overdue, but #Biopython 1.80 is out https://pypi.org/project/biopython/1.80/ - expect formal announcement later https://mailman.open-bio.org/pipermail/biopython/2022-November/016950.html - conda packages soon too! Thank you to all the contributors

NEW BARTMAN LAB WEBSITE JUST DROPPED: https://bartmanlabpenn.squarespace.com/
Techs/staff scientists/postdocs/students, come work with us in 2023!
(pls retoot =)

Alright Mastodon let's do this.
#Introduction I'm Dr. Liz Haynes. You might know me as @actin_crazy on twitter. I'm a Morgridge post-doctoral researcher studying #neurodegeneration and #neurodevelopment using #zebrafish and #microscopes! I am all about #openaccess and #opensource solutions. I get to hang out with the cool folks working on ImageJ2 at the Laboratory for Optics and Computational Instrumentation (LOCI) at UW-Madison. Follow me for the pretty pictures, stay for the science!

@mikelove Post about papers, blogs and repos you are reading. What made Science Twitter useful for me a grad student was to put research in front of me from outside of my own citation graph, and provide some context for why someone would care about it.

Hi all! I'm a postdoc, about to start my lab at Penn studying metabolic fluxes in tumor and immune cells! Also i like bad science puns!