Thiago Carvalho @cyrilpedia@qoto.org
I've worked on all of science, from B cells to T cells.
https://fellowsherpa.com
Joined Nov 2022
"To characterize cell-type-specific transcriptional heterogeneity in active Crohn’s disease, we profiled 720,633 cells from the terminal ileum and colon of 71 donors with varying inflammation status."
#Immunology #MucosalImmunology #crohnsdisease
https://www.cell.com/immunity/fulltext/S1074-7613(23)00012-2
"The current model for GVHD holds that disease is maintained through the continued recruitment of alloreactive effectors from blood into affected tissues. Here, we show, using multiple approaches including parabiosis of mice with GVHD, that GVHD is instead primarily maintained locally within diseased tissues."
Sacirbegovic et al @ImmunityCP https://www.cell.com/immunity/fulltext/S1074-7613(23)00013-4
Etching by Madalena
"We have no one to blame but ourselves if we don’t give people credit for collaborating - when we hire them, when we promote them, when we give them our respect and recognition as scientists."
@CoriBargmann on the #EMBOPodcast
https://www.embo.org/podcasts/our-special-feature-as-humans-is-communication/
"Considering the vastness and complexity of Amazonia, it is hard to see how Wallace could have gained the insights he did after working in the region for only four years, had he not paid close attention to local knowledge."
"The paper costume prints are mostly made from real costumes (with the exception of the long dress, which is a smaller scale model) , worn by actors in a film project and subsequently smashed, inked and printed on cotton paper."
Colograph by Madalena
"The team hypothesised that some of the T cells specific to SARS-CoV-2 had been activated by a herpesvirus called human #cytomegalovirus (HCMV). This pathogen is highly prevalent in the population and has also been linked to changes in the severity of #COVID19 symptoms (Alanio et al., 2022). To investigate, they stimulated pre-pandemic blood samples with different segments of SARS-CoV-2 proteins. This led them to discover a population of ‘cross-reactive’ CD4 and CD8 T cells that can recognize epitopes from both #SARSCoV2 and #HCMV"
Relic of my thesis defense dinner 20 years ago.
File under things you find cleaning the hard drive of your old computers :)
Me, Martin Weigert, Mel Cohn, Antonio Coutinho and (most important of all) my mother.
Great movie - the two leads give wonderful performances, and so does Kerry Condon.
Brief warning: it has some very funny moments, but it is not a comedy (much less a "buddy movie").
Print by Madalena & Constança Arouca
"Map 2 The Outer Hebrides Palimpsest (Edinburgh, Scotland, 1677)
This map is part of a series commissioned by King James VI during his attempt to pacify the “most barbarous Isle of Lewis”. It is of little strategic interest, as it charts two nearby uninhabited islets of no economic significance, but it has one unique feature: the engraver was clearly working from a palimpsest in vellum and decided to copy into the plate the still legible underlying text – a text which has absolutely no connection to the region depicted (it appears to be a list of penances compiled by the Observant Franciscan Friars of Aberdeen)."
As Teddy KGB said, "pay that man his money"
https://www.ft.com/content/c42189e0-4069-4e17-8dc0-72544dc1d51b
"In the early 2000s, a series of groundbreaking studies began revealing yet another facet of that mystery — the way mushrooms respond to sound, despite having no auditory organs."
https://www.themarginalian.org/2022/11/13/mushrooms-sound-waves/
Madalena made this illustration for a piece I wrote about Charles Lindbergh, who designed a perfusion pump for organ transplantation and published it in JEM 1935.
https://madalenaparreira.com
#HistoryScience #HistoryOfScience #ScientificIllustration
https://rupress.org/jem/article/62/3/409/4051/AN-APPARATUS-FOR-THE-CULTURE-OF-WHOLE-ORGANS
I've worked on all of science, from B cells to T cells.
https://fellowsherpa.com
Joined Nov 2022
