"Our data provide a model where the global shutdown of protein synthesis and subsequent rebooting mediated by miR-10b-5p downregulation is a hallmark of the dedifferentiation stage of limb regeneration."
"The cheap servant
It is against the law for black servants to live under the same roof as their employers. In a private home, servants would have a separate little room in the backyard. She lives on the edge of opulence, while her own world is bare. Newspapers are her carpet, fruit crates her chairs and table."
fm 'Ernest Cole’s photographs of 1960s South Africa during apartheid' in the FT
https://www.ft.com/content/9919a741-9115-460c-b541-405b1ef2ab32
Scribbling about spillovers with my stylish bat-print pen pouch by Madalena
"Ópera de Manaos (Brasil). ¿Un aria de Verdi en el corazón de la selva? Pues sí. Manaos es la ciudad más grande del Amazonas, un incongruente reducto de urbanización en medio de la jungla. Su famoso teatro de la ópera se inauguró en 1986, en pleno auge del caucho en la región, y simboliza la opulencia que en su día tuvo esta urbe brasileña. Los artesanos y la mayor parte de los materiales utilizados (mármol y vidrio italianos y hierro escocés) llegaron de Europa; la madera es brasileña, pero se talló en Portugal. La carretera de la entrada se hizo de goma para silenciar los vehículos que llegaran tarde a la función. El Festival de la Ópera del Amazonas dura tres semanas entre abril y mayo y lleva el 'bel canto' a las profundidades de la Amazonia."
Great fun discussing classic immunology papers with @marcdionne's class at Imperial yesterday - but very happy to be doing it in person next week!
'When presented to the immune system as either ex vivo-loaded dendritic cells or expressed from a viral vector, lncRNA-derived peptides drove a potent antigen-specific CD8 T lymphocyte response, which translated into a significant delay in tumour growth.'
Origin stories:
"I asked (Bert Vogelstein & Ken Kinzler), 'What prompted you to hire a naive undergraduate from Australia?'
I'd put on my CV 'hobbies: bushwalking', which is hiking in Australian.
They said that they were so intrigued by someone who bushwalked that they needed to meet me."
Tracy Bryan, co-discoverer of ALT, a classic @embojournal paper, on the #EMBOPodcast
Illustration by Madalena Parreira for an interview I did with @matthewcobb a few years ago (a really interesting conversation about how he began writing non-technical books, "Then I suddenly came up with this idea of rather than write the biography, why not concentrate on this huge row that broke out in 1672 over who was the first to discover that women have eggs?")
"This series of prints was created between 2017 and 2021 and consists of several aquatints of stages, doors, caves or forests, where figures have been inserted through the technique of chine-collé, and colours added through viscosity printing.
The same plate receives different figures or cut-outs (found in old cards, magazines or books) which affect the perception of the space through their different graphic qualities and scale."
#Prints #Print #Printmaking #handmade #ArtMastodon #Aquatint
Opening in a moment at Museu Nacional de Arte Contemporânea do Chiado: “I-II-III-IV-V cinco décadas do Ar.Co - Centro de Arte e Comunicação Visual”
http://www.museuartecontemporanea.gov.pt/pt/programacao/2054
'Altogether, our study identifies an unappreciated site of Yersinia colonization within the murine intestinal mucosa, and reveals an essential function for inflammatory monocytes in maintainance of pyogranuloma architecture during Yp infection.'
fm @BrodskyLab et al
#InfetionImmunity #Plague #Yersinia #Immunology #InnateImmunity
'Blockade of the inhibitory FcγRIIB in combination with anti–PD-L1 improved antitumor responses. Similarly, afucosylation of the IgG1 Fc region improved antitumor responses, and this was due to alterations in the tumor microenvironment.'
When your frenemies get the last word.
(from "Apropos of Nothing in the NYRB https://www.nybooks.com/articles/2022/07/21/absence-and-nothing-stephen-mumford/ )
My favorite case in the history of biology is Cuvier's eulogy of Lamarck, which you can read 👇
https://victorianweb.org/science/science_texts/cuvier/cuvier_on_lamarck.htm
A tiger for art lovers and Clive Barker fans by @hunchbacksociety
#ceramics #ceramic #ceramicart #handmade #ArtMastodon
I've worked on all of science, from B cells to T cells.
https://fellowsherpa.com