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"I want to see the worm weep and mope around because he can never be a proper husband to the woman he fell in love with 10 seconds ago. I want to see a gender-swapped version of the question, “Would you still love me if I were a worm?” tackled on the big screen once and for all."
Cover art detail from a 1981 French edition of God Emperor of Dune Image: Pocket Books.

polygon.com/23716984/god-emper

"Frankey turns any unassuming spot in the city — a street sign, an oddly shaped brick, a ledge — into something more playful."
Photo Credit: Jurre Rompa

nytimes.com/2024/03/01/travel/

Portuguese catupiry substitute. This must be what the kids call a "lifehack".

'An explosive rise in dengue cases in Brazil has health authorities on edge. In the first two months of 2024, the country registered more than one million cases of the mosquito-borne disease. That’s a record for this period — and Brazil’s dengue cases normally peak between March and May'

nature.com/articles/d41586-024

'No dia 16 de Maio, levaram-na à sala da tortura, no Reduto Sul, controlado pela polícia política. “Tens duas vias: a do sacrifício e a da colaboração”, disse-lhe o inspector. “O resultado será o mesmo. Por aquela porta não sais sem falar.”'

publico.pt/multimedia/interact

'By the late 1980s, EDRF was identified as NO by Ignarro (8) and independently by Moncada (9), and its vasorelaxing properties were found by Murad to be a consequence of guanylyl cyclase activation (10) via binding to the enzyme’s prosthetic heme group.'

jci.org/articles/view/176747

I love this quote from Denis Villeneuve & it holds true for editing manuscripts:

"There’s a specific moment when you know that the movie’s finished because you try to correct the editing and the movie bites you back."

(Photo:Chantal Anderson/The New York Times)

nytimes.com/2024/02/21/movies/

Mechanisms of metastasis.

'Together, our data show that glucocorticoids released during chronic stress cause NET formation and establish a metastasis-promoting microenvironment. Therefore, NETs could be targets for preventing metastatic recurrence in cancer patients, many of whom will experience chronic stress due to their disease.'

cell.com/cancer-cell/fulltext/?

'As if this quest isn’t hard enough, biologists cannot agree on what a species is. A 2021 survey found that practicing biologists used 16 different approaches to categorizing species. Any two of the scientists picked at random were overwhelmingly likely to use different ones.'

nytimes.com/2024/02/19/science

"Illustration of evolutionary mechanisms enabling eukaryotic acquisition of innate immune machinery from bacteria. Gray background illustrates bacterial sequences, with transition to white background indicating inheritance by eukaryotes. Through analysis of the evolutionary history of CD-NTase, STING, and viperin proteins, Culbertson and Levin highlight 3 broad mechanisms of eukaryotic immune gene evolution: vertical inheritance from LECA (green clade), horizontal gene transfer to specific eukaryotic clades groups (blue, pink, and tan clades), and convergent domain shuffling where similar accessory domains (red with white hashes) are found fused to the same immune gene (tan clade)."

journals.plos.org/plosbiology/

'The center of the movie, however, is the music. Tavernier, Maxine Gordon writes, “insisted that all the music would be recorded live as the musicians were filmed.” The musicians in “ ’Round Midnight” don’t play watered-down jazz. Although the numbers are condensed, much shorter than is usual on records or in concerts, the performances themselves are almost all full-strength, unadulterated modern jazz.'

newyorker.com/culture/the-fron

"With this perspective, our intent is to provide some orientation—and some sense of calm—while navigating the diversity of CRISPR tools, recognizing what needs to be done to make them better and tackling the technical, regulatory and other challenges. Inspired by Douglas Adams’ classic scientific-fiction comedy novel The Hitchhiker’s Guide to the Galaxy (1979), this article is our attempt to provide a brief, and hopefully informative, tour with this hitchhiker’s guide to the universe of -based editing tools in bacteria."
Krink et al @emboreports
embopress.org/doi/full/10.1038

"Antivaccine perceived experts are therefore overrepresented on Twitter compared to the share of actual biomedical experts who oppose COVID-19 vaccines, which may lead observers to underestimate the scientific consensus in favor of COVID-19 vaccination, in turn reducing vaccine uptake"

academic.oup.com/pnasnexus/art

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