Show newer

"Since the acquisition, the company's only actions have been to silence critics of Elon, to expose journalists and others to harm, and to violate basic ethical standards and privacy laws." futurism.com/elon-musk-twitter #Twitter

New commentary from Lisa Bauer and Debbie van Riel:

"Do SARS-CoV-2 Variants Differ in Their Neuropathogenicity?"
doi.org/10.1128/mbio.02920-22

A smart, nuanced review of the literature, which concludes:

"We urgently need fundamental insight into the molecular mechanism of the neuropathogenesis of SARS-CoV-2 infections. Although different mechanisms can result in neuropathology, virus entry into the CNS and infection of CNS cells is an important one."

#virus #virology #SARSCoV2 @virology

I get the sense that this man is just not taken seriously enough.

'Human history can be viewed as a slowly dawning awareness that we are members of a larger group. Initially our loyalties were to ourselves and our immediate family, next, to bands of wandering hunter-gatherers, then to tribes, small settlements, city-states, nations. We have broadened the circle of those we love. We have now organized what are modestly described as super-powers, which include groups of people from divergent ethnic and cultural backgrounds working in some sense together — surely a humanizing and character building experience. If we are to survive, our loyalties must be broadened further, to include the whole human community, the entire planet Earth. Many of those who run the nations will find this idea unpleasant. They will fear the loss of power. We will hear much about treason and disloyalty. Rich nation-states will have to share their wealth with poor ones. But the choice, as H. G. Wells once said in a different context, is clearly the universe or nothing."

~ Carl Sagan

(Book: Cosmos amzn.to/3kGZpGp)

Excited & proud to share the work of #PeijunMa, a longtime friend & collaborator who led (in #DebHung's lab @broadinstitute) the development of BacDrop (🥁), a high-throughput droplet-based scRNAseq method for bacteria, just out @cellcellpress

cell.com/cell/fulltext/S0092-8

(To be clear, I'm sharing this bc afaik I'm the only author active #onhere; Peijun & Deb led the work. I'm happy to have played a supporting role & super excited to see where the field goes next.)

Brief 🧵 (1/n):

Relic of my thesis defense dinner 20 years ago.
File under things you find cleaning the hard drive of your old computers :)

Me, Martin Weigert, Mel Cohn, Antonio Coutinho and (most important of all) my mother.

The wealthy know how to protect themselves and don't think COVID is mild

While most governments and public health organizations are downplaying the severity of #COVID and relying on a vaccine only strategy, do you know who is taking COVID precautions much more seriously? #DavosSafe 🧵 1/

For the one page easier to share version you can read at: pingthread.com/thread/16182238

@albertcardona @NicoleCRust @CoriBargmann

In which case the fly DSCAM locus would have more 'genes' than many organisms :)

Great movie - the two leads give wonderful performances, and so does Kerry Condon.

Brief warning: it has some very funny moments, but it is not a comedy (much less a "buddy movie").

'Even so, the challenge of making such a ‘living drug’ from a person’s cells extends beyond complicated designs. Safety and manufacturing problems remain to be addressed for many of the newest candidates. “There’s an explosion of very fancy things, and I think that’s great,” says immunologist Michel Sadelain at the Memorial Sloan Kettering Cancer Center in New York City. “But the complexity cannot always be brought as described into a clinical setting.”

nature.com/articles/d41586-023

Fun story about nature surprising the scientists. I learned this one from an excellent #EMBOPodcast with @CoriBargmann & @cyrilpedia.

embo.org/podcasts/our-special-

The era was the human genome project (late 1990s). In question: how many genes do we have? Going in, they knew that a worm (with 302 neurons) had ~13K genes. The presumption was that we, with our billions of neurons (and other complexities), would have a lot more.

GeneSweep was the official betting pool, organized by Cold Spring Harbor. Of the 460 (presumably well informed scientists) who entered the competition, the winner was the one who made the SMALLEST guess (~25K). The mean guess was 62K; someone guessed as high as 200K.

The small number of genes in the human genome (25K) surprised nearly everyone.

en.wikipedia.org/wiki/GeneSwee

nytimes.com/2000/05/23/science

On this day in 1922: Robert Holley born, won 1968 #NobelPrize for interpretation of genetic code and its role in protein synthesis #ThisDayInBiotech

Plant Cell webinar: Plant responses to abiotic stress. Feb 7, 3:00 PM GMT.
plantae.org/plant-cell-webinar
Climate change is leading to increased exposure to abiotic stresses for plants. Register for this webinar to hear three strories of how reseach is addressing these stress responses.

Show older
Qoto Mastodon

QOTO: Question Others to Teach Ourselves
An inclusive, Academic Freedom, instance
All cultures welcome.
Hate speech and harassment strictly forbidden.