#introduction
Hello #neuro peeps!
A bit late to the party but finally here and hoping to reconnect.
I'm currently a postdoctoral #neuroscientist at the Sainsbury Wellcome Centre (SWC) at #UCL and will soon open my lab at the Department of Physiology, Development & Neuroscience (PDN) at #Cambridge University. My primary research interest is the #neurobiology of #selfmotion and #navigation. I use cellular and systems approaches including #neurophysiology, #circuit dissection and #behaviour to understand how the mammalian #brain (mouse model) constructs the sense of self-motion and orientation from various incoming information, particularly #vision and the #vestibular sense.
Mystery of #fatal ‘staggering #disease’ unravelled: novel #rustrela virus causes severe #meningoencephalomyelitis in domestic #cats https://www.nature.com/articles/s41467-023-36204-w
Review at EJI
"Dysregulation or overproduction of IL-6 leads to autoimmune diseases such as multiple sclerosis (MS) and rheumatoid arthritis (RA), in which Th17 cells are considered to be the primary cause of pathology. Given the critical role of IL-6 in altering the balance between Treg and Th17 cells, controlling IL-6 activities is potentially an effective approach in the treatment of various autoimmune and inflammatory diseases."
#Immunology #Treg #Th17 #Autoimmunity
https://onlinelibrary.wiley.com/doi/full/10.1002/eji.201040391
Ancient caviar
"Few families of plants or animals have survived more geological upheaval than the Acipenseridae. Sixty-six million years ago, when the Chicxulub asteroid hit what is today known as the Yucatán, Acipenseriformes swam the warm sea that bisected North America."
https://www.nytimes.com/2023/02/02/magazine/they-outlasted-the-dinosaurs-can-they-survive-us.html
After the February 5, 1783, #earthquake that hit the Italian provinces of Reggio Calabria & Sicily, a 30 km long fault escarpment was observed along the Aspromonte mountain. This is the first drawing of a ruptured fault ever published.
#NewStudy “Vaccines were generally estimated to be effective against severe outcomes caused by SARS-CoV-2 Omicron infection, this analysis found that protection in older patients was more likely to wane 6 months after the second dose. Hence, a booster dose is recommended for older patients to restore immunity” #covid19 https://jamanetwork.com/journals/jamanetworkopen/fullarticle/2800935
Raab is the nightmare ignorant bully boss we all loathe.
Dominic Raab: more civil servants in bullying complaint than previously thought
https://www.theguardian.com/politics/2023/feb/05/dominic-raab-more-civil-servants-in-bullying-complaint-than-previously-thought?CMP=Share_AndroidApp_Other
Cover image by Madalena Parreira for JEM in 2016, based on a paper by Kuchmiy et al, "NLRP2 controls age-associated maternal fertility"
Hello, again! Some reintroductions in order now I've moved servers to zirk.us.
I'm Will Buckingham, a #writer based in #Dundee with a background in #philosophy and #anthropology. My latest book is HELLO, STRANGER (Granta 2021) — an exploration of the arts of #hospitality through philosophy, anthropology, #history & #culture.
I'm on the faculty at Parami University in #Myanmar and run Wind&Bones, a social enterprise working worldwide on projects about #writing, #creativity & #socialchange.
'Despite being one of the more sophisticated programs ever to run on my laptop, Whisper.cpp is also one of the simplest. If you showed its source code to A.I. researchers from the early days of speech recognition, they might laugh in disbelief, or cry—it would be like revealing to a nuclear physicist that the process for achieving cold fusion can be written on a napkin.'
https://www.newyorker.com/tech/annals-of-technology/whispers-of-ais-modular-future
@cyrilpedia i think if we just keep increasing the total number of cells, the UMAPs shape will start resembling the organ they come from, right?
@dmaseda I think that hypothesis deserves funding!
Not the point of the paper, but this intro bit was news to me:
"Indeed, the host immunity-boosting phenotype may explain the initial spread of Wolbachia in previously uninfected populations. In nematodes, elimination of Wolbachia induces host sterility, and antibiotic treatment is an effective addition to pharmacological treatment of human-infecting, #Wolbachia-positive filarial nematodes"
https://journals.plos.org/plosbiology/article?id=10.1371/journal.pbio.3001972
"These are not ordinary conservatives. They are extremist politicians who seem to celebrate the period of brutal military dictatorship, when, beginning in 1964, the military dissolved Congress, suspended constitutional rights, and imposed extensive censorship; democracy was not restored until 1985. They claim that the great mistake of the military regime was “to torture but not kill,” as Bolsonaro himself declared in 2016."
cc @mucida
https://www.nybooks.com/articles/2023/02/23/brazil-at-the-crossroads-vanessa-barbara/
Weekend in Nice learning about ageing, #telomeres & #zebrafish with @miguelgf
Assistant Professor in Immunology @UWEauClaire
Come join us at #UWEC as an #Immunologist in the #Biology Department!
#ScienceJobs #job #immunology, #pui, #tenuretrack, @uwecbiology
Eau Claire #UnitedStatesUS #FacultyMembe...
https://jobrxiv.org/job/university-of-wisconsin-eau-claire-27778-assistant-professor-in-immunology/?feed_id=36525
"If the governor of Florida wants a culture war, he should get one. Students and faculty must resist right-wing efforts to remake liberal arts education. The right can be defeated."
https://www.currentaffairs.org/2023/02/fight-fiercely-new-college
February 4, 1857, German anatomist Hermann Schaaffhausen publicly announces the discovery of the Neanderthal Man💀
"This review aims to consolidate past and current studies investigating the complexity of the miRNA interactome to provide the reader with a mechanistic view of how miRNAs shape macrophage behavior."
I've worked on all of science, from B cells to T cells.
https://fellowsherpa.com