Thiago Carvalho @cyrilpedia@qoto.org
I've worked on all of science, from B cells to T cells.
https://fellowsherpa.com
Joined Nov 2022
Thiago Carvalho
boosted
Applications are still open for our 2023 Fellows program. Join the program to learn more about #preprints and connect with others interested in bringing positive change to science communication. Read more & apply: https://buff.ly/3Dy4dor
Thiago Carvalho
boosted
Past exposure to viruses shapes T cell responses to subsequent viruses, even if completely unrelated?! 🤔
V interesting #virology #immunology #viruses #Tcells
Cross-reactivity of SARS-CoV-2– and influenza A–specific T cells in individuals exposed to SARS-CoV-2
Thiago Carvalho
boosted
Intriguing: a risk score for identifying patients at low risk of bacterial meningitis. This is always an issue and with real #antimicrobialstewardship opportunity #AMR
#IDMastodon #MedMastodon
Thiago Carvalho
boosted
Our EiC @npariente is attending the EMBO Workshop “The Immune System of Bacteria”, the first nucleating this vibrant community studying various systems that has so exploded in recent years.
Come by to say hello!
Thiago Carvalho
boosted
Share to Mastodon 2.0 by is now available!
#Mastodon #Edge #Chrome #Firefox #extension by
@corbin
https://blog.corbin.io/post/710160748534530048/share-to-mastodon-20-is-now-available
Technical language
'Mental-health care is “a shitstorm,” Thomas Insel, a former director of the National Institute of Mental Health, told me. “Nobody likes what they get. Nobody is happy with what they give. It’s a complete mess.”
https://www.newyorker.com/magazine/2023/03/06/can-ai-treat-mental-illness
Thiago Carvalho
boosted
Astronomy Picture of the Day
Crescent Moon Beyond Greek Temple https://apod.nasa.gov/apod/astropix.html
'Meloni’s government has actively sabotaged the NGO-led search and rescue missions attempting to save lives at sea. Under her government’s new legislation, boats that have rescued migrants onboard cannot remain at sea to continue their mission. They must go to assigned ports based in northern Italy by Italian authorities, days of sailing away from the main theatre of operations. This has resulted in a drastic reduction of the time the vessels can engage in saving lives, and surely a corresponding increase in the death rate.'
'Three days before Christmas, the only hospital in this remote city on the Yakama Indian Reservation abruptly closed its maternity unit without consulting the community, the doctors who delivered babies there or even its own board.'
https://www.nytimes.com/2023/02/26/health/rural-hospitals-pregnancy-childbirth.html
Thiago Carvalho
boosted
Escalators don’t break.
They just become stairs.
Review on HIF and stromal-tumor interactions by Missiaen et al @embojournal
"In this review, we discuss how HIF-mediated mechanisms control nutrient sensing and availability in the TME, the competition for nutrients, and the metabolic cross-talk between tumor and stromal cells."
Thiago Carvalho
boosted
RT @rnartist_app
After two weeks of coding, preview of my new tool to visualize the folding pathways of an #RNA during its transcription. Pathways are computed with my new #rustlang algorithm. Visualization and GUI are made with #kotlin, #javafx and my rnartistcore library. #bioinformatics
Thiago Carvalho
boosted
Research Assistant in Leukemia
Join the lab to work on the metabolism of T-ALL in Montreal!
#ScienceJobs #job #leukemia #metabolism
Montreal #Canada #ResearchAssistant
https://jobrxiv.org/job/sainte-justine-research-center-27778-research-assistant-in-leukemia/?feed_id=39402
Thiago Carvalho
boosted
Interesting piece in Nature about the type 1 #diabetes drug Teplizumab, the first that the FDA has ever approved to delay the onset of the disease:
I wrote about the drug in mid December for #NatureMedicine
Thiago Carvalho
boosted
A Retired Math Teacher Helps Students Learn Geometry Through Quilting
https://www.openculture.com/2023/02/a-retired-math-teacher-helps-students-learn-geometry-through-quilting.html via @openculture
Bat biotech
"Inspired by the humble and much maligned bat, Paratus is hoping to study the unique characteristics that have evolved in the only flighted mammal over millions of years to solve afflictions such as inflammation, viral infection and more."
https://www.fiercebiotech.com/biotech/paratus-launches-100m-and-mission-embrace-bat
"Here, we demonstrate the induction of both systemic and mucosal antibody responses against HuNoV in suckling mice using recombinant Rhesus rotaviruss expressing HuNoV VP1 or P domain."
#MucosalImmunology #Immunology #rotavirus
Thiago Carvalho
boosted
"Here we report a murine model that expresses tumor-like levels of human APOBEC3B after Cre-mediated recombination. Animals appear to develop normally with full-body expression of APOBEC3B. However, adult males manifest infertility and older animals of both sexes show accelerated rates of tumorigenesis (mostly lymphomas or hepatocellular carcinomas)"
Thiago Carvalho
boosted
Does accumulation of #macromolecules in the highly protein-rich #mitochondrial matrix regulate solute diffusion and biochemical reactions?
Using FRAP analysis of #organelle-targeted fusion peptides, Werner Koopman and colleagues report macromolecular crowding as a stress-dependent determinant of matrix mobility and viscosity
Thiago Carvalho
boosted
01/2023 Issue ➡️ http://bit.ly/3CMpyKi
On the cover: Engineered bacteria expressing a designed single-chain IL-10 prevent severe inflammation in Pseudomonas aeruginosa lung infection
Luis Serrano lab, CRG
#proteinengineering #immunomodulation #synbio #SystemsBiology
I've worked on all of science, from B cells to T cells.
https://fellowsherpa.com
Joined Nov 2022
