“Postpartum psychosis has been around for thousands of years, and yet it is not an official disease category in the DSM-5,” Veerle Bergink, the director of the Women’s Mental Health Program at Mount Sinai, told me. “There is no money for it, not for research, not for treatment. There are no guidelines. This is one of the most severe conditions in psychiatry, one that has huge impacts on the mother and potentially on the child, and there’s nothing.”
"Banks fail. When they do, those who stand to lose scream for a state rescue. If the threatened costs are big enough, they will succeed. This is how, crisis by crisis, we have created a banking sector that is in theory private, but in practice a ward of the state."
https://www.ft.com/content/09bfbb8d-22f5-4c70-9d85-2df7ed5c516e
Now available: 50 travel awards for students, postdocs, and members of underrepresented groups for Metascience 2023 at the National Academies in Washington DC, May 9-10.
Apply by March 20th, 4p ET. It is super easy: https://docs.google.com/forms/d/e/1FAIpQLScBQQeOtGCMFHwF9Cjce-cneVWDwLWaJj0kDVaNf5ldGrCHBw/viewform
Conference information: https://metascience.info/
Please share!
Follow up study from Iain Mathieson and colleagues rebutting the recent paper on allele frequency changes pre/post Black Death
https://www.biorxiv.org/content/10.1101/2023.03.14.532615v1
'While The Times praised him as “one of the nation’s outstanding chemists” in its obituary, today Midgley is best known for the terrible consequences of that chemistry, thanks to the stretch of his career from 1922 to 1928, during which he managed to invent leaded gasoline and also develop the first commercial use of the chlorofluorocarbons that would create a hole in the ozone layer.'
https://www.nytimes.com/2023/03/15/magazine/cfcs-inventor.html
"We used a single-cell approach to retrieve the phenotype and TCR sequence of infected cells in blood and lymphoid tissue from individuals at the earliest stages of HIV infection. HIV initially targeted a few proliferating memory CD4+ T cells displaying high surface expression of CCR5."
Gantner et al @ImmunityCP
RT @PauliGroup
Are you excited about RNA? Then check out our international Microsymposium on RNA Biology, held again @viennabiocenter from May 3-5.
Abstract submission deadline for selected talks from students/postdocs: March 23!
https://www.oeaw.ac.at/imba/seminars-events/microsymposium/programme
Please RT!
'What’s unusual about the COVID-19 pandemic is not so much that there have been conspiracy theories and rejection of conventional science by the nonscientist public (both of which have been traveling companions of the scientific enterprise since its beginnings); rather, what makes this “infodemic” distinctive is that it’s the first during which the public has had direct access to much of the science itself.'
"He snapped a photo of a drawing he’d made in a notebook — a crude pencil sketch of a website. He fed the photo into GPT-4 and told the app to build a real, working version of the website using HTML and JavaScript. In a few seconds, GPT-4 scanned the image, turned its contents into text instructions, turned those text instructions into working computer code and then built the website. The buttons even worked."
https://www.nytimes.com/2023/03/15/technology/gpt-4-artificial-intelligence-openai.html
The abandoned communicable disease hospital at Ellis Island
Gallery/info: https://www.abandonedamerica.us/ellis-island-communicable-disease-hospital
Horizontal Gene Transfer, Fitness Costs and Mobility Shape the Spread of Antibiotic Resistance Genes into Experimental Populations of Acinetobacter Baylyi https://doi.org/10.1093/molbev/msad028 #science #evolution #biology #genome #SciComm #evolgen_paper
GCaMP8 is out!
"Fast and sensitive GCaMP calcium indicators for imaging neural populations", by Y. Zhang, M. Rózsa, et al. 2023. https://www.nature.com/articles/s41586-023-05828-9
"‘jGCaMP8’ sensors, based on the calcium-binding protein calmodulin and a fragment of endothelial nitric oxide synthase, have ultra-fast kinetics (half-rise times of 2 ms) and the highest sensitivity for neural activity reported for a protein-based calcium sensor."
Tested in both larva and adult #Drosophila, and in mouse.
Great cover
"On the cover: A radial glial progenitor cell stands, sculpted out of cherry wood by Louis-Jan Pilaz."
'However, the mechanisms that maintain choriodecidual immune homeostasis or compromise immune barrier functions remain unclear. To understand these processes, a two-chamber microphysiological system (MPS) was created to model the human choriodecidual immune interface under normal and infectious conditions in vitro.'
Batf stabilizes Th17 cell development via impaired Stat5 recruitment of Ets1-Runx1 complexes
Casey Weaver, Robin Hatton and coworkers
The latest episode of the #EMBOPodcast is out, I discuss #OpenAccess, #OpenScience and the danger of amplifying existing inequities with Bernd Pulverer & Thomas Lemberger from @EMBOPress and Alicia Kowaltowski from the University of São Paulo.
🎧 👇
Register until April 23, 2023 to be part of the EuSARC meeting to meet in Vienna in May! https://ccri.at/eusarc/
I've worked on all of science, from B cells to T cells.
https://fellowsherpa.com