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'Different versions of this horror have happened again and again in history. They’re still happening in places like Rwanda, Bosnia, Kosovo and East Timor, wherever one group of people permits its leaders to convince them that for their own protection, for the safety of their families and the security of their country, they must get their enemies, those alien others who until now were their neighbors.'

commongood.cc/reader/a-few-rul

'It is obvious that there had, indeed, been a better part of German society. If not, the Nazis would not have already needed to fill prisons and concentration camps with political opponents in 1933, years before the deportation of Jewish people began. But the identification of the anti-Nazi opposition with the conspirators that tried to kill Hitler and take power in July 1944 has always been historically dishonest. The military was certainly not the group that had sacrificed most members in the resistance against Hitler. Instead, it was the necessary element in exporting Nazi crimes from Germany to the rest of Europe.'
jacobin.com/2024/07/stauffenbe

'MALAT1 is a highly abundant long non-coding RNA (lncRNA) that is retained in the nucleus (Sun and Ma 2019). It is consistently highly expressed across mammalian species, and its function is related to splicing regulation, the cell cycle, or the structure of the nuclear speckle (Hutchinson et al. 2007; Sun and Ma 2019). We found that MALAT1 expression is highly correlated with the DropletQC nuclear fraction measure and thus can be used to identify poor quality cells from scRNA-seq datasets. MALAT1 expression is an important technical signal that easily and quickly indicates the presence of a nucleus in droplets in scRNA-seq data.'
biorxiv.org/content/10.1101/20

'In the end, Bell Labs was ultimately undermined by the very technologies that it had created. The world that Bell Labs thrived in no longer exists: to push technological progress forward, we'll need to understand both why Bell Labs worked and why it no longer could.'
(via The Browser)

construction-physics.com/p/wha

'Combining our amphioxus dataset and publicly available data from the mouse, zebrafish, tunicate, sea urchin and sea anemone, we uncovered a tripartite origin of the chordate CNS from anterior, posterior and NMP populations (Extended Data Fig. 7c).'

nature.com/articles/s41559-024

'Our results imply that nervous systems converged onto synaptic density invariance to stabilise neuronal responses, suggesting a simplifying principle for neural circuit function, assembly and evolution.'

biorxiv.org/content/10.1101/20

If a drug to achieve longevity is ever discovered, it is highly unlikely to work on women, because labs across the world are filled with white mice who are exclusively male.

Yet the sex differences between rodents are highly significant.

Reflecting a profound sex bias, 'Methuselah's Zoo' author Dr. Peter Austad says more progress has not been made in extending women’s healthy longevity because researchers are not interested in studying it.

theguardian.com/science/articl

#woman #health #aging

#sciences #biology Are animals conscious? We’re finally realising that many species are
Science is at last confirming what many people have long suspected - that mammals, birds and perhaps some invertebrates have elements of consciousness quantamagazine.org/insects-and

Head-to-head comparison of aptamer- and antibody-based proteomic platforms in human cerebrospinal fluid samples from a real-world memory clinic cohort medrxiv.org/content/10.1101/20

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#proteomics #prot-preprint

'We discovered that the Neisseria gonorrhoeae transcriptional response to PMNs has features in common with the transcriptional response to nutrient metals and oxidative stress, which enhance Neisseria gonorrhoeae resistance to hydrogen peroxide & polymorphonuclear leukocytes.'

journals.plos.org/plospathogen

#IDMastodon #immunology #SARSCoV2 evolution prompts the quest for other protective antibody mechanisms beyond neutralization .Non-neutralizing mAbs might target epitopes with less evolutionary selection pressure to mutate in #SARSCoV2 variants VS neutralizing mAbs

cell.com/trends/immunology/ful

"I reflect on my own PhD candidature to illustrate how article processing charges disempower doctoral candidates." - Article processing charges suppress the scholarship of doctoral students ese.arphahub.com/article/12417

Timothy Snyder on "both sides" - a cult of duality which we should have learned from by now. Have seen people get sucked into fascist thinking because of this.

snyder.substack.com/p/both-sid

✳️Producing #green #hydrogen for industrial & transport applications🔋

♻️By utilising 100% renewable #electricity, #Luxembourg Hydrogen Valley (LuxHyVal) will produce green hydrogen locally & implement initiatives across the entire value chain by 2026.
➡️researchluxembourg.org/en/luxh

LuxHyVal is a collaborative project of 17 partners from 7 countries. If successful, the project aims to expand its initiatives to the #CzechRepublic & #Ukraine️

#ResearchLuxembourg #research #renewableenergy

'We unexpectedly found that cRel abundance and B cell proliferation are not proportional, but have a complex relationship in which some characteristics of proliferative clonal expansion are enhanced by cRel but others are diminished. We show that this may underlie the proliferation phenotypes of marginal zone vs. follicular B cell subsets.'

pnas.org/doi/10.1073/pnas.2309

'In many European capitals, the average rent for a one-bedroom apartment is more than the median income of a young person. In 2023, houses in the UK were more expensive than they’d been since 1876. In the United States, home prices are up 60 percent over the last decade.'

jacobin.com/2024/07/housing-cr

'In this review of a diverse literature, we show how host control mechanisms influence almost every aspect of microbiome biology. Our focus is the mammalian microbiome, but we also examine well-characterized examples from invertebrate and plant microbiomes. To begin, we explore the biology of host control, including immunity, barrier function, physiological homeostasis, transit, and host behavior.'
science.org/doi/10.1126/scienc

'While Japan lacks its own homegrown AI giants, some tech companies are drawn to the market for another reason: the country’s copyright law which critics say allows widespread use of copyrighted images and other materials for commercial purposes to train AI models without seeking permission.'
ft.com/content/f9e7f628-4048-4

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