Thiago Carvalho @cyrilpedia@qoto.org
I've worked on all of science, from B cells to T cells.
https://fellowsherpa.com
Joined Nov 2022
Thiago Carvalho
boosted
RT @EricTopol
Rare genetic disorders in the interferon pathway and life-threatening Covid
https://www.jci.org/articles/view/166283 @jclinicalinvest by @casanova_lab and @MAndersonUCSF
Thiago Carvalho
boosted
New #EvolutionPaper #preprint with @iochromaland on the evolution of the #flavonoid pathway in the Petunieae clade of #Solanaceae. We use multivariate phylogenetic comparative methods to analyze quantitative measures of #GeneExpression and floral flavonoid #pigment content in a phylogenetic context. We find that #evolutionary transitions in floral pigmentation appear to be largely underpinned by shifts in gene expression, and uncover tradeoffs between pathway branches. https://ecoevorxiv.org/repository/view/4991/
"Three years into the pandemic, the immune systems of the vast majority of humans have learnt to recognize SARS-CoV-2 through vaccination, infection or, in many cases, both. But just how quickly do these types of immunity fade?"
Thiago Carvalho
boosted
@cyrilpedia
These papers are so important. Fabulous resource, especially given the challenges of getting these samples and costs of the single cell sequencing #crohnsdisease #immunology #IMMastodon #mucosalimmunology
Thiago Carvalho
boosted
RT from the bird app our labs first peer-review paper at @cellhostmicrobe
https://twitter.com/Mucus_Man/status/1621534562693136384?t=Zhc2IkbT2i4ig0vHZI3QhQ&s=09
Thiago Carvalho
boosted
In case you’ve ever wondered what we’re doing in the lab, here is a preview -> Comparison of commercial DNA extraction kits for whole metagenome sequencing of human oral, vaginal, and rectal microbiome samples #bioRxiv #microbiome #microbiology #DNAextraction #shotgunsequencing #metagenomics #kitbias
Thiago Carvalho
boosted
Understanding the impact of #climatechange and also #oceanacidifcation on
#marine #ecosystems requires study across multiple trophic levels.
This valuable new review explores the importance of #zooplankton and their response to #climatechange highlighting the likelihood of increases in CO2 from zooplankton respiration but a number of knowledge gaps to address.
Find out more in Nature Communications on:
Thiago Carvalho
boosted
RT @Caroline_Bartma
Excited to share an updated version of my postdoc work, where we found that solid tumors make ATP slower than most healthy tissues https://www.nature.com/articles/s41586-022-05661-6 https://twitter.com/Caroline_Bartma/status/1445468983059124233
“Declaring the public-health emergency over would give governments and some public-health agencies permission to look away and move on to other things,” says Mark Woolhouse, an epidemiologist at the University of Edinburgh, UK. “It remains a very significant public-health problem. About a quarter of the world is still unvaccinated, and that’s potentially a lot of vulnerable people.”
"Here, we have developed a robust computational framework to determine the prognostic strengths of a variety of molecular features relative to conventionally utilized clinical factors such as tumor stage, age, and histopathology across a vast compendia of cancer cohorts from TCGA."
https://www.cell.com/cell-genomics/fulltext/S2666-979X(23)00018-6
'As global demand for Covid-19 vaccines dries up, the program responsible for vaccinating the world’s poor has been urgently negotiating to try to get out of its deals with pharmaceutical companies for shots it no longer needs.
Drug companies have so far declined to refund $1.4 billion in advance payments for now-canceled doses, according to confidential documents obtained by The New York Times.'
'Munch was a different musician under studio conditions than he was live, Holoman writes, and he controlled his most explosive tendencies in the hope of making records that would last. Even his two incendiary Boston readings of Berlioz’s “Symphonie Fantastique,” his trademark piece, come nowhere close to the maelstrom he inflamed onstage.'
https://www.nytimes.com/2023/02/02/arts/music/charles-munch-conductor.html
Thiago Carvalho
boosted
RT @s_tavazoie
Prognostic cancer modules are superior to single-gene predictors of disease progression. From the brilliant team of Balaji Santhanam and Panos Oikonomou. @Columbia, @Columbia_Bio
https://www.cell.com/cell-genomics/fulltext/S2666-979X(23)00018-6
Thiago Carvalho
boosted
NEW ARTICLE: Twenty Screenplays by Women to Download for Free and Study
After my friend writer-director Liz Garcia challenged a fellow filmmaker's list of great screenplays for lacking any by women, I culled the internet and assembled this list of twenty brilliant scripts by women you can download for free and study.
Read: https://medium.com/@cole.haddon/on-screenwriting-twenty-screenplays-by-women-to-study-898caa6f47ba
#screenwriting #screenwriter #writing #storyteller #film #movies #cinema #cinephile #writerscommunity #writinglife #amwriting #CreativeWriting
Thiago Carvalho
boosted
The 1st results for the @BharatBiotech nasal vaccine (BBV154, approved in India) randomized trial vs shots now posted, superior antibody and cellular immune response (vs ancestral and Omicron); 4-fold less side effects https://papers.ssrn.com/sol3/papers.cfm?abstract_id=4342771
Thiago Carvalho
boosted
Competence in #Streptococcus controls genetic transformation, biofilm formation & virulence. @JWVeening &co show that it's also crucial for host #adherence, involving the fratricin CbpD, which exposes #virulence factors to the cell surface #PLOSBiology https://plos.io/3DtTwmJ
I've worked on all of science, from B cells to T cells.
https://fellowsherpa.com
Joined Nov 2022
