Thiago Carvalho @cyrilpedia@qoto.org
I've worked on all of science, from B cells to T cells.
https://fellowsherpa.com
Joined Nov 2022
Thiago Carvalho
boosted
Revisiting the Design of the Long-Term #Evolution Experiment with Escherichia coli
https://link.springer.com/article/10.1007/s00239-023-10095-3
"According to Neruda’s family, a new forensics report conducted by a group of international experts has concluded that he was poisoned while already gravely ill—a victim, most probably, of the Chilean military he had politically opposed."
'A new study offers a glimpse of the future by looking to the past. Mosquitoes that transmit malaria in sub-Saharan Africa have moved to higher elevations by about 6.5 meters (roughly 21 feet) per year and away from the Equator by 4.7 kilometers (about three miles) per year over the past century, according to the study.'
"We observed increased TGFβ-mediated induction of FoxP3+ cells in the presence of extracellular lactic acid, in a glycolysis-independent, acidity-dependent manner."
Thiago Carvalho
boosted
one of our all-time favorite posts from 2009(!)
The Limitations of LB Medium
by Hiroshi Nikaido
LB medium, also known incorrectly as Luria-Bertani medium, is widely used to grow bacterial cultures, mainly because it is easy to prepare and provides a broad base of nutrients. LB broth contains, per ml, 10 mg tryptone...
Read more → https://schaechter.asmblog.org/schaechter/2009/11/the-limitations-of-lb-medium.html
Thiago Carvalho
boosted
RT @FranciscoICMC
Our new preprint: Estimating the impact of the COVID-19 pandemic on dengue in Brazil.
https://assets.researchsquare.com/files/rs-2548491/v1/34fea422c663bb14a014b9e4.pdf?c=1675924900
We estimated the gap between expected and observed dengue cases using an interrupted time series design with a neural network and a structural Bayesian time series model.
'What doctors eventually found inside the sample — inside the baby's respiratory tract — has fueled a shift in scientists' understanding of how pandemics begin and made them reconsider the way they search for new threatening viruses. It has made them realize there could be an easier, more efficient way to find viruses like SARS-CoV-2 before they evolve into a global nightmare.'
https://www.npr.org/sections/goatsandsoda/2023/02/15/1152892721/how-to-stop-pandemics
Thiago Carvalho
boosted
#openscience will play an important role in the peer review process for the #sti2023 conference. Find out more in this new blog post! https://www.leidenmadtrics.nl/articles/experimenting-with-open-science-practices-at-the-sti-2023-conference
Thiago Carvalho
boosted
Capybara in an Uruguayan coin
by javilasa in r/capybara
Link: https://reddit.com/r/capybara/comments/111w3ia/capybara_in_an_uruguayan_coin/
Thiago Carvalho
boosted
My latest for The Nation.
The Fight for the Soul of American Medicine
More and more physicians are rejecting the forces of conservatism within their field and joining the grassroots movement to revolutionize American medicine. Featuring Suhas Gondi, Sanjay Kishore, Don Berwick, Eric Reinhart, J. Michael McWilliams. #medicine #publichealth #finance #SDoH
https://www.thenation.com/article/society/doctors-american-medicine-public-health/
"Las leches de fórmula, como muchos otros productos de consumo, utilizan la ciencia para venderse. Algunas de las atribuciones más frecuentes son que benefician el desarrollo del cerebro o del sistema inmunológico del bebé o que favorecen su crecimiento. Sin embargo, según un artículo publicado hoy en la revista BMJ, la mayor parte de esas virtudes saludables que aparecen en los paquetes o en los anuncios de los sustitutos de leche materna tienen escasa o ninguna evidencia científica."
My latest Clinical Pipeline column for #NatureMedicine is out, a look at Moderna's RNA vaccine for RSV & a survey of what's, well, in the pipeline, for RSV immunotherapies, including vaccines and monoclonals.
#Vaccine #drugdiscovery #drugdevelopment #mRNA #RSV #immunology #MonoclonalAntibody
Thiago Carvalho
boosted
PROTAC degraders Rock! Read this application to the #Polycomb BMI and RING1B proteins:
Targeted Degradation of PRC1 Components, BMI1 and RING1B, via a Novel Protein Complex Degrader Strategy.
https://doi.org/10.1002/advs.202205573
Thiago Carvalho
boosted
"The area of sea ice around Antarctica has hit a record low, with scientists reporting “never having seen such an extreme situation before”.
https://www.theguardian.com/world/2023/feb/15/antarctic-sea-ice-hits-record-low-climate-crisis?CMP=share_btn_tw
Thiago Carvalho
boosted
Exciting news: UMass is hiring a new professor for our program and the rank is open for both Assistant and Associate. The link to apply is: https://careers.umass.edu/amherst/en-us/job/517690/assistantassociate-professor-college-of-education-remp
Please share with any outstanding psychometricians you know who may be interested in working in one of the best and most productive measurement programs in the world
Thiago Carvalho
boosted
#WHO aims to accelerate trials of vaccine candidates for #Marburg disease
https://healthpolicy-watch.news/who-accelerate-vaccine-marburg/
Thiago Carvalho
boosted
Nonrandomised controlled trial in recurrent glioblastoma patients: the promise of autologous tumour lysate-loaded dendritic cell vaccination
Thiago Carvalho
boosted
RT @fchalmel
We are looking for an enthusiastic PhD student to join our team and work on the development of the urogenital tract by using single-cell and spatial transcriptomics.
Please do not hesitate to contact us !!
Thiago Carvalho
boosted
Harvest in Bourgogne (France 1963). Vendemmia in Borgogna (Francia 1963). Photo: Hans Silvester. #BlackAndWhitePhotography
Thiago Carvalho
boosted
Exciting new paper in @PLOSBiology — we show that plasmids use translational global regulators to rewire host cells including expression of key ecological traits, like metabolism and motility, whilst also boosting horizontal transmission of the plasmid
This was a big collaborative effort with colleagues at John Innes Centre, Birmingham, Sheffield & Liverpool
#plasmid #HGT #MobileGeneticElements
https://journals.plos.org/plosbiology/article?id=10.1371/journal.pbio.3001988
I've worked on all of science, from B cells to T cells.
https://fellowsherpa.com
Joined Nov 2022
