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“When the doctors switched off the life support machines, his mom climbed into bed beside him and I held my son’s hand as he passed away,” Puerta says. “This wasn’t an overdose because Daniel didn’t know what he was taking. He was intentionally deceived. He was poisoned.”

ft.com/content/bd1b1614-8407-4

Blood Vessel Organoids for Development & Disease

Self-organizing capillary blood vessel + (+Astrocyte for )

Transplant to gain vascular hierarchy

Organotypism Through Genetic Drivers

Dr. Josef Penninger lab Circ Res 2023
ahajournals.org/doi/10.1161/CI

Saint in Pamplona realizes what happened to Jake Barnes in "The Sun Also Rises"

#OtD 20 Feb 1988 20k people in Manchester marched against Margaret Thatcher's homophobic section 28 law, which made it illegal for public bodies to "promote" homosexuality, including teaching its "acceptability" in school

Notch signaling in development and homeostasis

In their 'Development at a glance' article and poster, Oren Gozlan and David Sprinzak provide a brief overview of the Notch signaling and function in development and homeostasis

journals.biologists.com/dev/ar

This is *not* the way scientific papers typically begin:
_________________________

We are running out of time. Ecosystems across the planet are being destroyed at an accelerating rate. The life sciences – once a field dedicated to the study of living systems and our interactions with them – are increasingly becoming sciences of the dead. Up to one million species are currently threatened with extinction, many of them within decades.
_________________________

It's a very good sign, however, an indication that at least some scientists are now ready to speak boldly and unequivocally about the greatest emergency our species has ever faced.

SEE THE FULL PAPER -- elifesciences.org/articles/832

#ClimateEmergency #BiodiversityLoss #Extinction

"El laboratorio de David Baker en la Universidad de Washington (Estados Unidos) va un paso más allá. Ha desarrollado varios sistemas de inteligencia artificial abiertos que crean proteínas que nunca han existido en la naturaleza."

elpais.com/ciencia/2023-02-19/

Le Floc’h et al at Regeneron generated an anti-common gamma chain monoclonal that blocks signaling.

"Treatment of nonhuman primates with REGN7257 suppressed NK cells and T cells without affecting granulocytes, erythrocytes, or platelets."

science.org/doi/10.1126/scitra

RT @sivajothy
The call for symposia at ICE (The International Congress of Entomology) in Kyoto 2024 is now open. ( shorturl.at/cxyA8 ). please retweet.

📢 Don't miss: Tuuli Lappalainen @tuuliel_lab (@nygenome @KTHuniversity @scilifelab) will speak at our #DahlemColloquium!

📜 Functional variation in the human #genome: lessons from the #transcriptome
📆 27. FEB, 11:00 AM (CET)
📍 @MPI_MolGen, #Berlin
🔗 molgen.mpg.de/events/33625/396

Deadline for applications to the Summer internship for INdigenous peoples in Genomics (SING) workshop to be held this year together with Diné College and Northern Arizona University is extended to February 28.

Apply here: singconsortium.org/

#NativesInSTEM #IndigenousSTEM #IndigenousScience #IndigenizeSTEM

MDPI's IJMS just sent me an email just to say they published a paper and I could read it if I wanted to. Heck, if I wanted to submit an article, they'd be pleased as punch.

I wasn't a reviewer. I had no involvement at any point. This is just spam. Specifically, it's "rent-seeking" behaviour from a publishing group nearly everyone deems "predatory."

See: bit.ly/1yrPredPub

#MDPI #PredatoryPublisher #AcademicChatter

Some objects you have to share immediately after seeing it: a Roman flask in the shape of a fish.
We don't know what flaks in the shape fishes were used for, maybe the shape relates to the content (garum/fish sauce), maybe it was used to hold oil.

On display at Pierides Museum, Larnaka, Cyprus.

Photo: Jeff Amadon via Flickr

#RomanArchaeology

Serendipity & the discovery of tyrosine kinases:

"In analysing the phosphoaminoacids released by partial acid hydrolysis of polyoma virus middle T phosphorylated in vitro, Hunter used an old batch of pH 1.9 electrophoresis buffer; it so happens that phosphothreonine and phosphotyrosine do not separate on electrophoresis at pH 1.9 in acetic acid/formic acid/water buffer, but do separate at the lower pH of ‘aged’ buffer, from which the more volatile acetic acid has escaped (T Hunter, personal communication; Ushiro and Cohen, 1980)."

nature.com/articles/1208077

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