Thiago Carvalho @cyrilpedia@qoto.org

Batf stabilizes Th17 cell development via impaired Stat5 recruitment of Ets1-Runx1 complexes

Casey Weaver, Robin Hatton and coworkers

https://www.embopress.org/doi/10.15252/embj.2021109803

Mid-March, 1852, Victorian naturalist Alfred Russel #Wallace reaches the village of Mucura in #Colombia as the first European, the westernmost point of his 4-year long South #America expedition spent collecting insects, birds & rocks🐞🐦🪨

https://tinyurl.com/3rmvedek

Register until April 23, 2023 to be part of the EuSARC meeting to meet in Vienna in May! https://ccri.at/eusarc/

Expanding a statistical approach called Mendelian randomization to include multiple variables may help researchers to identify new molecular causes of specific traits. https://elifesciences.org/articles/86416?utm_source=mastodon&utm_medium=social&utm_campaign=organic_insights

Targeted Protein Upregulation of STING for Boosting the Efficacy of Immunotherapy

https://onlinelibrary.wiley.com/doi/10.1002/anie.202300978

'A big reason people don’t stay in public health is money. Salaries are small. Bureaucracies are large. Since the pandemic, abuse has also been on the rise. And in more than half the states, lawmakers have curtailed public health experts’ ability to make and carry out policies. Castrucci said that’s like using a jackhammer to shatter our own collective safety.'

https://www.politico.com/newsletters/politico-nightly/2023/03/07/were-not-prepared-for-the-next-public-health-crisis-00085993

Interesting new paper from Orian Shirihai's group in @embojournal
"Inhibition of ATP synthase reverse activity restores energy homeostasis in mitochondrial pathologies"
https://www.embopress.org/doi/full/10.15252/embj.2022111699

Orian & I discussed his classic work on the mitochondrial life cycle (also published in EMBO J) on an episode of the #EMBOPodcast 🎧 👇

#mitochondria #mitophagy #metabolism

https://www.embo.org/podcasts/fuse-or-die-a-conversation-with-orian-shirihai/

Interview (in Portuguese) with my friend @joanagsa
on equality, implicit bias, and the pernicious myth of meritocracy in academia.

"No entanto, é raro encontrar o mesmo nível de escrutínio ou de julgamento quando gerações de homens brancos promovem outros homens brancos porque são da mesma família ou porque os pais eram amigos de infância. Porque nos lembramos mais de uns casos do que de outros, o nosso cérebro constrói uma narrativa que se perpetua."

https://activa.sapo.pt/mulheres-inspiradoras/2023-03-08-dia-da-mulher-palavras-de-joana-goncalves-de-sa/#&gid=0&pid=1

Behold 900+ Magnificent Botanical Collages Created by a 72-Year-Old Widow, Starting in 1772

https://www.openculture.com/2023/03/behold-900-magnificent-botanical-collages-created-by-a-72-year-old-widow-starting-in-1772.html

A shrine among trees on a moor #utagawahiroshige #ukiyoe https://www.wikiart.org/en/hiroshige/a-shrine-among-trees-on-a-moor

A study weighs introducing a transmissible vaccine against rabies to vampire bats. The candidate virus causes lifelong infections in bats and could serve as a vaccine vector, reducing the size, frequency, and duration of rabies outbreaks by 50 to 95%. In PNAS: https://www.pnas.org/doi/10.1073/pnas.2216667120

Postdoc in experimental evolution @IdeevL

A #PostDoc researcher position (12 month, renewable once) in #ExperimentalEvolution is available from June 2023.

https://jobrxiv.org/job/universite-paris-saclay-ideev-institute-of-ecology-and-evolution-egce-27778-postdoc-in-experimental-evolution/?feed_id=40460

#ScienceJobs #job @INRAE_Bioger @UnivParisSaclay #evolution #genomi...
https://jobrxiv.org/job/universite-paris-saclay-ideev-institute-of-ecology-and-evolution-egce-27778-postdoc-in-experimental-evolution/?feed_id=40460

My latest Clinical Pipeline column for #NatureMedicine is now online. A new take on heart failure using iPSC derived cardiomyocytes.

#drugdevelopment #cardiology #stemcells #regeneration

https://www.nature.com/articles/d41591-023-00027-5