Genius concept 😍🤓 — a conference for all the tough topics in #DataScience and #ML we all struggle with but nobody talks about in public. 👉 normconf.com #NormConf
Sampled talk titles:
➡️Five semesters of linear algebra and all I do is solve Python dependency problems (Tim Hopper)
➡️Data ethics: the non-sexy parts (Roy Keyes)
And maaany more!!! 👀 👇👇👇
Coffee drinkers! Listen! Starbucks workers nationwide are starting a 3-day strike today (Friday 12/16) as part of their effort to unionize.
How can you help? Don't cross the picket line. Get your coffee elsewhere. (Preferably at independent coffee shops. Long live small biz).
And spread the word! Make this message viral. Let's hold billionaire corps accountable because worker's rights are human rights. Let's go.
For Beethoven’s birthday, here’s an ancient recording of me playing his violin concerto
There are funded places available for early-career researchers at our Workshop on #gut #physiology.
Apply by 13 January 2023 to join us for 'Inside Out: New Frontiers in the Comparative Physiology of the Vertebrate Gut', organised by Carol Bucking and Chris Wood.
The Workshop takes place from 25-28 June 2023 at Eastwell Manor, Kent, UK. Find out more and apply here:
https://biologists.com/workshops/jun-2023/
@J_Exp_Biol #Co_Biologists #ComparativePhysiology #BiologistsWorkshops #ECR #Opportunities
On Beethoven's birthday, his stirring letter to his brothers about the loneliness of living with deafness and how music saved his life https://www.themarginalian.org/2017/02/08/beethoven-romain-rolland-letters/
I'm a computational neuroscientist (#Neuroscience #CompNeuro) and science reformer based at Imperial College London.
I like to build things and organisations that make it easier to do better #science.
I made the Brian spiking neural network simulator (https://briansimulator.org) with @romainbrette and @mstimberg.
I co-founded #Neuromatch with @kordinglab and a bunch of others, and the SNUFA community with @fzenke.
In my main research, I'm interested in how the brain uses spikes to carry out computations, and what advantages that might have. Increasingly, my work revolves around using methods from #MachineLearning because that finally lets us build models that actually require intelligence, the unique property of the brain I'm interested in.
I also want to make science better. Neuromatch's mission is to democratise science, and with our new open #publishing initiative (https://nmop.io) I'm hoping we'll be able to dramatically change the murky world of academic publishing.
You might (ha!) also see some political commentary from me. I'm a left-wing #anarchist.
Happy to discuss any of the above!
Interesting preprint on the perspective of early career researchers: https://www.biorxiv.org/content/10.1101/2022.12.06.519378v1
Two quotes:
“constant pressure to write mediocre papers that are flawed and unread, advancing a meaningless metric in pursuit of individual benefit.”
“My data has been extensively doctored/falsified by my supervisor in successful grant applications. This was discussed with senior colleagues who agreed it was major issue but are reluctant to act due to direct and indirect reliance on my supervisor.“
Finally, my #introduction !
I'm a freelance science writer and editor writing mostly about #climatechange, #earthscience, #conservation, #forestconservation, and #ecologicalrestoration. Soon, I'll publish more pieces on #energy, #wildlifeconservation, and #immigrantculture.
I'll be sharing my science writing here and my favorite #narrative #nonfiction. But I'm really more excited about sharing #garden and #pet photos. If you #compost and keep a worm bin, let's chat!
Cheers,
Natasha
The IL-1 cytokine family continues to amaze with its complexity.
Here IL-37 cleaved by neutrophil elastase 👉 bind to IL-36 receptor 👉 inflammation.
RT @RosieRedfield@twitter.com
The 2023 Gordon Conference on Microbial Population Biology (July 9-14) program is finalized; please apply early at http://grc.org! @vscooper@twitter.com and I are now fundraising so we can cover expenses for as many people as possible. We'd appreciate suggestions of who to ask.
'Here, we develop an optimised cytosine base editing system for gene inactivation in Drosophila through predictable C-to-T editing and identify temperature as a crucial parameter for base editing efficiency. We find that activity of an evolved version of the most widely used APOBEC1 deaminase is attenuated within the temperature range commonly used for culturing Drosophila (18-29°C) and many other ectothermic species. In contrast, an evolved CDA1 domain functions with remarkable efficiency within the same temperature range.'
'The lack of a confirmed director raises some problems. Lawrence Tabak has done a commendable job as interim NIH director, but it is time for some new faces after the lengthy Collins administration. (Tabak was an NIH deputy director and the deputy ethics counselor under Collins.) Furthermore, there are key appointments still to be made within the agency, most visibly, a successor to Anthony Fauci, who will leave the directorship of the National Institute of Allergy and Infectious Diseases at the end of the year.'
@mikethemadbiologist this is my all time favorite post on your blog. I still laugh when I read it.
https://mikethemadbiologist.com/2022/10/27/mehmet-oz-and-the-ghost-of-mel-carnahan/
Hello Mastodon! I'm a behavioral scientist with a passion for eye-tracking and open science. Trying to understand how people collaborate and decide in social dilemma situations. In my spare time, I enjoy long walks to the fridge pretending to be interested in a healthy snack while fantasizing about ice cream.
Looking forward to connecting with you and learning more about your research and experiences.
'This article (...) provides detailed protocols for the preparation of single-cell suspensions from various mouse nonlymphoid tissues, including skin, intestine, lung, kidney, mammary glands, oral mucosa and transplantable tumors, and instructions for multiparameter flow cytometry analysis of DC subsets.'
Hey everyone!
My name is Jason Kirk and I am the director of the Optical Imaging & Vital Microscopy core facility at the Baylor College of Medicine in Houston, TX.
I am a microscopist and photographer interested in all things imaging. I am a big proponent of microscopy education and frequent poster of #FluorescenceFriday images.
Speaking of #FluorescenceFriday - here is my first Mastodon image:
Now imagine you’re the governor of the state with the country’s largest population over 65. Perhaps you’d want to make sure that you’re protecting your state’s seniors from falling into that gap. Except that governor is Ron DeSantis of Florida, who just proved, yet again, that he is America’s most cynical elected official, exploiting pandemic-era foolishness to further vaccine mistrust simply for political gain."
Just arrived here. Still not sure how this works though.. #science #immunology #HSCT #treg #lymphocytes #celltherapies #immunemodulation #CMV #GVHD will all these #s help me to get content I'm keen on?
A few years ago we showed that restriction-modification systems shape gene flow within species. Now we show how plasmids cope with these systems to spread across bacterial populations. Small plasmids avoid restriction sites, large plasmids recruit counter-defenses (methylases). And the plasmids most avoiding restriction sites have the broadest host ranges. Great collaboration in a project led by Liam Shaw and Craig MacLean. https://www.biorxiv.org/content/10.1101/2022.12.15.520556v1
I've worked on all of science, from B cells to T cells.
https://fellowsherpa.com