Thiago Carvalho @cyrilpedia@qoto.org
I've worked on all of science, from B cells to T cells.
https://fellowsherpa.com
Joined Nov 2022
Thiago Carvalho
boosted
Referenced link: https://www.nature.com/articles/s44222-023-00044-6
Discuss on https://discu.eu/q/https://www.nature.com/articles/s44222-023-00044-6
Originally posted by Nature Portfolio / @NaturePortfolio: http://nitter.platypush.tech/NaturePortfolio/status/1649797478743506946#m
A Review in @natrevbioeng discusses genetic tools and systems for the plant-based production and engineering of biopharmaceuticals, including vaccines and monoclonal antibodies. 🔒 https://www.nature.com/articles/s44222-023-00044-6
Thiago Carvalho
boosted
Hunting submarines.
'Here, we report that CD8+T cells maintain the capacity to kill tumor cells that are entirely devoid of MHC-I expression. This capacity proves to be dependent on interactions between T cell NKG2D and tumor NKG2D ligands (NKG2DL).'
#Preprint #immunology #immunooncology #immunotherapy
Thiago Carvalho
boosted
Can the effects of globalization be separated from those of technological change? How have they interacted to widen inequality?
We'll explore these questions and more in Class 3 of my Wealth and Poverty course, available here: https://bit.ly/43PNnwx
Thiago Carvalho
boosted
"We simply cannot be a country where your access to the care you need is determined by the whims of ideologically driven judges and lawmakers without medical or scientific training."
This Could Be One of the Most Brazen Attacks on Americans’ Health Yet https://www.nytimes.com/2023/04/20/opinion/abortion-pill-case-supreme-court.html?smid=tw-share
Thiago Carvalho
boosted
#Raab had to go - but investigation wasn't needed. PM bought time to avoid consequences of unethical cabinet appointments. He'd have known of Raab's bullying, Braverman's breaking of Ministerial Code & Qs re Zahawi's tax affairs from day 1. Still appointed them all. He's culpable
RT @DominicRaab: My resignation statement.👇
🐦🔗: https://n.respublicae.eu/CarolineLucas/status/1649336285046161410
Thiago Carvalho
boosted
'A democracia é de todos e isso é muito bonito. Mas também é bonito cada um saber qual é o seu lugar e a sua seara. Ver a direita portuguesa arrogar-se o papel de defender as comemorações do 25 de Abril da presença de um político de esquerda, como Lula da Silva, é como ver alguém opor-se à presença de um aniversariante na sua festa de anos.'
https://www.publico.pt/2023/04/19/opiniao/opiniao/lula-silva-porteiros-25-abril-2046608
Thiago Carvalho
boosted
Research technician - Brain Cancer Research -
Come join the new lab @UMich for an exciting research technician position to study #braintumor in an interdisciplinary research environment!
#ScienceJobs #job #genomics, #brai...
https://jobrxiv.org/job/university-of-michigan-27778-research-technician-brain-cancer-research/?feed_id=43218
'In the Ts65Dn mouse model for DS, where DSCAM is overexpressed due to DSCAM triplication, GABAergic innervation of PyNs by basket and chandelier interneurons is increased. Genetic normalization of DSCAM expression rescues the excessive GABAergic innervations and the increased inhibition of PyNs. Conversely, loss of DSCAM impairs GABAergic synapse development and function.'
https://journals.plos.org/plosbiology/article?id=10.1371/journal.pbio.3002078
'Two affirmative action lawsuits facing the court—against the University of North Carolina (UNC) and Harvard University—will likely have severe ramifications for medical training and health equity. Given the likelihood that the Supreme Court will end affirmative action, medical institutions must plan how to further diversity without incurring liability.'
It was a pleasure to reconnect with José Roberto de Toledo of Brazil's Piauí magazine a couple years after participating in his Portuguese language Pandemic Podcast, "Luz no fim da Quarentena" (ht @mucida).
On UOL's Análise de Notícia we talked about the new #malaria and #RSV #vaccines.
👇 Starts around min 27 (in Portuguese)
Thiago Carvalho
boosted
An exceptional Bionics Institute pod.🎙️
CEO Robert Klupacs has an inspiring chat with Professor Anne Kelso AO about her international research career in immunology, leadership of the National Health and Medical Research Council (NHMRC), discovery versus commercialisation in Australia, role models & mentors, and gender equity. ☕️
Tune in here: https://www.bionicsinstitute.org/podcasts-videos/taking-affirmative-action-to-achieve-equity-in-science-with-professor-anne-kelso-ao/.
Thiago Carvalho
boosted
The American Medical Association steps up. We all need to speak out. This isn't just about abortion drugs, it's about bringing down the entire system of regulation of drugs in the US. The AMA gets it. https://www.nytimes.com/2023/04/20/opinion/abortion-pill-case-supreme-court.html
Thiago Carvalho
boosted
Very proud to share our latest manuscript on #coronavirus HKU1 spike opening, triggererd by a small sugar molecule:
https://www.biorxiv.org/content/10.1101/2023.04.20.536837v1
#cryoEM #virology #glycotime #structuralbiology
Thiago Carvalho
boosted
RT @kuriosera
It’s 👏🏼 finally 👏🏽 out 👏 immensely proud to be able to share this work from my PhD journey-now published in @CellReports 👇Keep reading if you want to see where my initial goal to learn how unconventional T cells recognise🦠infections has led us ⏬️ 1/n
https://www.cell.com/cell-reports/fulltext/S2211-1247(23)00264-4
"The biggest mystery is Bogner himself, who entered the influenza field in 2006 without any known links to research or science policy. Science’s investigation has found that Bogner has a checkered and murky past. Official documents list different birth dates. In his early 20s, Bogner was convicted of securities fraud—a previously unreported felony for which he spent time in jail—and had a falling out with a World Cup skier over funding and credit for an instructional video."
https://www.science.org/content/article/invented-persona-behind-key-pandemic-database
Thiago Carvalho
boosted
RT @AislingRehill
Delighted to share a pre print of my work looking at the intersection of inflammation, glycolysis and thrombosis. Thanks to all our collaborators for contributing to this exciting story! @rogerjspreston
@PrestonLab_RCSI @RCSIPharmBioMol @IrishCtrVascBio https://www.biorxiv.org/content/10.1101/2023.04.20.537683v1
"The National Institutes of Health hasn’t signed up a single patient to test any potential treatments — despite a clear mandate from Congress to study them. And the few trials it is planning have already drawn a firestorm of criticism, especially one intervention that experts and advocates say may actually make some patients’ long Covid symptoms worse."
Thiago Carvalho
boosted
CD8+ T cell activation in cancer comprises an initial activation phase in lymph nodes followed by effector differentiation within the tumor
Thiago Carvalho
boosted
'La investigadora percibiría cada año 70.000 euros en su cuenta bancaria si hacía constar esa institución árabe, la Rey Saúd de Riad, como su lugar de trabajo principal en una de las bases de datos que utiliza el influyente ranking de Shanghái para designar a las mejores universidades del planeta.'
I've worked on all of science, from B cells to T cells.
https://fellowsherpa.com
Joined Nov 2022
