Thiago Carvalho @cyrilpedia@qoto.org

The second coming of angiogenesis inhibitors?

"So far, dozens of clinical trials have evaluated checkpoint inhibitor-angiogenesis inhibitor combos. Some proved toxic, and others failed. However, the studies also led FDA to approve new therapies for types of liver, kidney, lung, and endometrial cancers. The drug combinations are not curative, but they restrain tumor growth. And some extend patients’ lives by many months over angiogenesis inhibitors alone."

https://www.science.org/content/article/failed-cancer-therapy-revived-powerful-tumor-killer-when-combined-newer-drugs#.ZGTEnbmFjTk.linkedin

Research Technician - Ackerman Lab
University of California, San Diego

See the full job description on jobRxiv: https://jobrxiv.org/job/research-technician-ackerman-lab/?feed_id=45878

#ScienceJobs #hiring #research
La Jolla #UnitedStatesUS #ResearchTechnician
https://jobrxiv.org/job/research-technician-ackerman-lab/?feed_id=45878

Just shared my reasons for leaving Twitter with a journalist:

Open positions in Jena, Germany to work on phages

A Postdoctoral fellowship in Viral Ecology: https://twitter.com/BEDutilh/status/1658810066336718850

A PhD student to study Bacteriophage Diversity: https://twitter.com/BEDutilh/status/1658810508022018049

A PhD student to study Microbiome Structure: https://twitter.com/BEDutilh/status/1658810854001745920

'MalariaGEN is now a global community, with more than 200 researchers in more than 40 countries. From the outset it embodied principles of openness and data sharing, with Dominic often travelling to partner institutions to establish mutual trust. Together with training and the development of laboratories, this helped to ensure that the researchers gained the capacity to lead their own studies and dispelled any suspicion that rich countries were exploiting the resources of less-wealthy ones.'

https://www.theguardian.com/world/2023/may/16/dominic-kwiatkowski-obituary

Online now: With Darwin towards complexity: a review of Domains and Major Transitions of Social Evolution https://www.cell.com/trends/ecology-evolution/fulltext/S0169-5347(23)00092-7?rss=yes&utm_source=dlvr.it&utm_medium=mastodon

Cephalopod Neuroscience Conference, April 17-21, 2024. MBL, Woods Hole, MA USA

Organized by Cristopher Niell, Caroline Albertin, Paul Katz, Robyn Crook, & Simon Sprecher

sites.google.com/view/cephneuro/

#neuroscience #cephalopods

The Whole Genome of Colletes collaris (Hymenoptera: Colletidae): An Important Step in Comparative Genomics of Cellophane Bees https://doi.org/10.1093/gbe/evad062 #science #evolution #biology #genome #SciComm #evolgen_paper

-DeSantis signed three anti-trans bills into law.
-The laws limit LGBTQ+ schools' curriculum and transgender care for minors.
-They also criminalize "opposite sex" restroom access in public buildings, schools, and parks.

This is NOT about 'protecting children' it is about inciting hate against a vulnerable & marginalized community to gain political power. We have seen this before and it does not end well. #Fascism101

https://www.businessinsider.com/desantis-authorizes-slew-of-anti-trans-laws-in-florida-2023-5?_gl=1*eli0xx*_ga*MTUwMzI3NDEyMi4xNjg0MzU3NDU2*_ga_E21CV80ZCZ*MTY4NDM1NzQ1Ni4xLjEuMTY4NDM1NzU4OS4xOC4wLjA.&r=US&IR=T

'The protest was started by Ilaria Lamera, an engineering student at Milan Polytechnic, before spreading to Rome and other cities including Florence, Bologna, Padua and Cagliari. Lamera had been commuting to university from her home town of Bergamo and when she started looking for a room to rent in Milan struggled to find one for below €600 (£520).'

https://www.theguardian.com/world/2023/may/12/italy-students-protest-over-cost-housing-high-rents

'Growing up to 15 centimetres high, with unassuming tan or yellow-green tops, death caps can taste quite nice, according to people who have accidentally eaten them and survived. But afterwards, the toxin can cause vomiting, seizures, severe liver damage and death.'

https://www.nature.com/articles/d41586-023-01630-9

"Public health experts say that when managing an infectious disease outbreak, communication is not part of the response. It is the response."

https://www.nytimes.com/2023/05/11/us/politics/covid-response-lessons.html?action=click&module=Well&pgtype=Homepage&section=Education

A 5th grade teacher in FL was investigated for showing a Disney movie with a gay character in it. She has resigned bc she's sick of the politics.

Is this the America you want? No?

Then help us vote these ghouls out.

With many chapters now under my belt, I'm seeing that every book chapter I write unfolds in a bit of the same way, on repeat. It always gets there but I just wish it were a bit less painful:

Early wave) This topic/idea is fascinating. No one's really written about this and I have so many questions. Wow! Did you know???!!!

Middle wave) Boo-hoo, this will never work; I have no idea what to do with this; none of this makes any sense or connects together in any useful way. I hate this topic. Given that I can write about anything I want, why did I decide on this? This is all garbage; it's all a disaster. I'm never going to finish this book.

Final wave) I get it now and it all makes so much sense - I see how it all fits. I am so in love with this material and this chapter. In fact, I think I'll redirect my future (book/research) toward this topic, it's so amazing.

On to the next chapter ...

Do other authors get as emotionally invested in the process as this? I have no idea how to make it to the good stuff in any other way. But sigh ...

#writing #nonfiction

Depression hits new high among Americans https://www.statnews.com/2023/05/17/depression-new-high-survey/?utm_medium=social&utm_source=mastodon&utm_campaign=mastodon_organic