Thiago Carvalho @cyrilpedia@qoto.org

#JamelleBouie gets it: “The denial of dignity to one segment of the political community…threatens the dignity of all. This was true for [Frederick] Douglass and his time…and it is true for us and ours as well. To deny equal respect and dignity to any part of the citizenry is to place the entire country on the road to tiered citizenship and limited rights, to liberty for some and hierarchy for the rest.”

https://www.nytimes.com/2023/02/10/opinion/trump-desantis-transgender-rights.html

The privatisation of #water firms has had a clear result:

1. to fund profits to #shareholders, investment was constrained;

2. low investment has led to the #watercrisis, #pollution & water losses through leaks;

3, (Finally) under-funding is to be rectified & funded via loans;

4. the ongoing costs of loans will be repaid by customers through higher bills.

The only thing the #investors have done is stolen our money, offering no actual benefits;

the #Tories' #kleptocapitalism in a nutshell!

A Florida woman was denied an abortion for her fetus with Potter syndrome which meant no survival outside the womb. She had to carry until 37 weeks & then go through labor, delivery, baby's death, funeral. ‘The law has created torture.’
https://www.washingtonpost.com/health/interactive/2023/florida-abortion-law-deborah-dorbert/

'Pot1 is a subunit of telomere capping complex that binds to the G-rich overhang and inhibits the activation of DNA damage checkpoints. In this study, we explore new functions of fission yeast Pot1 by using a pot1-1 temperature sensitive mutant'
@miguelgf et al

#telomeres #telomere

https://www.biorxiv.org/content/10.1101/2023.01.23.525167v1

"Anchovies are a good thing to love if you are able to."

https://www.youtube.com/watch?v=sVWBqy657TE

The district morons apparently have put together a great reading list:

"The district, which encompasses the city of Pensacola in Florida’s west and borders Alabama, withdrew a series of books including works by Penguin authors Toni Morrison, Kurt Vonnegut and Khaled Hosseini."

https://www.ft.com/content/dde3cc89-3463-4980-99df-899f2f5dcbec

Tools

" In this study, we used a CRISPR nuclease that targets a site within an exon of an essential gene and designed a cargo template so that correct knock-in would retain essential gene function while also integrating the transgene(s) of interest. Cells with non-productive insertions and deletions would undergo negative selection. This technology, called SLEEK (SeLection by Essential-gene Exon Knock-in), achieved knock-in efficiencies of more than 90% in clinically relevant cell types without impacting long-term viability or expansion."

https://www.nature.com/articles/s41587-023-01779-8

Tenure Track Assistant or Associate Professor

Indiana University

See the full job description on jobRxiv: https://jobrxiv.org/job/indiana-university-27778-tenure-track-assistant-or-associate-professor/?feed_id=45969

#ScienceJobs #hiring #research
Indianapolis #UnitedStatesUS #FacultyMember
https://jobrxiv.org/job/indiana-university-27778-tenure-track-assistant-or-associate-professor/?feed_id=45969

Going out to get me some Penguins today:

"Penguin Random House is suing a Florida school district for banning several of its books, in the latest pushback by companies and organisations against “anti-woke” actions by US political conservative"

https://www.ft.com/content/dde3cc89-3463-4980-99df-899f2f5dcbec

A Cohort of Scientists Is About to Be Crushed https://mikethemadbiologist.com/2023/05/18/a-cohort-of-scientists-is-about-to-be-crushed/

É com imensa emoção que recebo e partilho convosco o meu exemplar de A Saga/Fuga de J.B. editado pela Quetzal e com ilustrações minhas. O livro, que é já de si espectacular, está todo ele ilustrado por mim, num contínuo que abrange capa, lombada, contracapa, badanas, verso das badanas, interior da capa e contracapa. E ainda tem uns bonecos na página dois e no marcador! <3
Estou muito orgulhosa e muito agradeço ao Francisco José Viegas e ao Rui Rodrigues o convite, a confiança e todo o apoio.

Three conglomerates account for 90% of all generic drug buys.

#FDA has 10 people tasked to tracking and figuring out drug shortages.

Hmmm, what COULD the problem be? 🙄

#capitalism #regulatorycapture #USelessgovernment

Drug Shortages Near an All-Time High, Leading to Rationing - The New York Times https://www.nytimes.com/2023/05/17/health/drug-shortages-cancer.html

'By analyzing the genomes of 290 living people, researchers concluded that modern humans descended from at least two populations that coexisted in Africa for a million years before merging in several independent events across the continent. The findings were published on Wednesday in Nature.'
@Carl_Zimmer

https://www.nytimes.com/2023/05/17/science/human-origins-africa.html

“The carrion birds sat about the topmost corners of the houses with their wings outstretched in attitudes of exhortation like dark little bishops.”

#CormacMcCarthy #BloodMeridian #Books #Bookshelf #ClassicBooks #bookstodon