'Members of the Sackler family who own Purdue Pharma can be shielded from lawsuits linked to the US opioid crisis in exchange for payments worth up to $6bn, appellate judges have ruled in a reversal of a lower court’s decision.'
https://www.ft.com/content/823612fb-a365-4ffe-90b2-772435bf1d9b
Ian is thoughtful, trustworthy, and a decent coot. “Dr Virology”, who alerted me to SARS2 in January 2020.
From: @mackayim2022
https://mastodon.social/@mackayim2022/110460550089516375
In Editors' Choice this week in Science Signaling, we highlight the work of Ahn et al. in Cell. They investigated the adaptor protein ASC2 in bat immune cells. ASC forms aggregates in response to viral infection, resulting in inflammatory cytokine production. However, bat ASC2 suppressed this pathway. Mice expressing bat ASC2 had improved responses to viral infections. The findings suggest how bats may serve as viral reservoirs. Read a summary here: https://www.science.org/doi/10.1126/scisignal.adi8744 #viruses #immunology
When Coltrane was a member of the Miles Davis quintet, Davis confronted him about the duration of his solos "I don't know what it is," Coltrane said. "It seems like when I get going, I just don't know how to stop."
Davis said, "Why don't you try taking the fucking horn out of your mouth?"
'Indigenous populations are disproportionately affected by COVID-19, but are rarely studied. An investigation of the immune response of Australian First Nations people to SARS-CoV-2 vaccination and infection shows a major effect of comorbidities.'
Post-doctoral position - Oligodendroglial cells - Moyon lab @inp
Institute of NeuroPhysiopathology
Looking for a postdoctoral fellow to join a new neuroscience lab
See the full job description on jobRxiv: https://jobrxiv.org/job/institute-of-neurophysiopathology-27778-post-doctoral-position-oligodendroglial-cells-moyon-lab-inp/?feed_id=46858
#ScienceJ...
https://jobrxiv.org/job/institute-of-neurophysiopathology-27778-post-doctoral-position-oligodendroglial-cells-moyon-lab-inp/?feed_id=46858
"Basic research is ultimately what gives us the grounding for breakthroughs".
Our Magda Bienko, Group Leader in the #Genomics Research Centre, explains how and why she decided to embrace her research adventure at #HumanTechnopole to understand the architecture of human #DNA.
On @Nature Italy
#sciencemastodon #science #lifesciences #humangenome
IL6 is not always the bad guy.
"In the penumbrae of human stroke brain lesions, we identified a subpopulation of microglia that express vascular endothelial growth factor A. These cells, termed ‘repair-associated microglia’ (RAMs), were also observed in a rodent model of CVI and coexpressed interleukin (IL)-6Ra. Cerebrovascular repair did not occur in IL-6 knockouts or in mice lacking microglial IL-6Ra expression"
#Immunology #Inflammation #Microglia #Neuroimmunology
🔬 Hazuki Takahashi from RIKEN IMS explains how nanopore long-read #sequencing technology can change research on the #humangenome
#sciencemastodon #science #lifesciences #humantechnopole #nanopore @nanopore@genomic.social @nanopore@bird.makeup @riken_en
That revolutionary new fMRI technique for detecting neuronal activity (DIANA)? Guess what happened next.
https://pubpeer.com/publications/0EF432E4E7D84352E9B582CEC6DF07#1
bioRxiv preprints "contradictory results" are really useful. And whoever is posting them to PubPeer is perfoming a real public service, because it is difficult for readers to discover them.
Welcome move from #EMBO: "We now consider publications in #journals and #refereed #preprints equal" for the purpose of applying to be an EMBO Postdoctoral Fellow.
https://www.embo.org/features/refereed-preprints-in-applications-for-embo-postdoctoral-fellowships/
Flies galore:
Robber fly, Asilinae family https://www.inaturalist.org/observations/164682340
Bee fly, Bombylidae family, with an uncanny resemblance to a Calliphora fly https://www.inaturalist.org/observations/164650016
Bee fly, Lomatia sp. https://www.inaturalist.org/observations/164565745
#iNaturalist #Diptera #BeeFlies #Bombylidae #Asilinae #entomology #Crete #insects
'Members of the Sackler family who own Purdue Pharma can be shielded from lawsuits linked to the US opioid crisis in exchange for payments worth up to $6bn, appellate judges have ruled in a reversal of a lower court’s decision.'
https://www.ft.com/content/823612fb-a365-4ffe-90b2-772435bf1d9b
New posting! This one's about optics, but nothing to do with microscopy - instead it's asking whether we should perhaps view #scientists and not knowledge as the real (primary) product of #academic #research...and whether this provides a better rationalisation of the level of societal investment. Are research papers actually a by-product?
https://totalinternalreflectionblog.com/2023/05/30/whats-the-by-product/
'Indigenous populations are disproportionately affected by COVID-19, but are rarely studied. An investigation of the immune response of Australian First Nations people to SARS-CoV-2 vaccination and infection shows a major effect of comorbidities.'
"The European Commission and Pfizer have agreed a deal to cut the number of Covid-19 vaccines supplied to the EU, resolving tensions between the majority of member states over paying for shots that may not be used."
https://www.ft.com/content/eb4fe823-66bd-4e1a-8b96-13b8f8c3dce9
"Hundreds of thousands of low-income Americans have lost Medicaid coverage in recent weeks as part of a sprawling unwinding of a pandemic-era policy that prohibited states from removing people from the program."
I've worked on all of science, from B cells to T cells.
https://fellowsherpa.com