Thiago Carvalho @cyrilpedia@qoto.org

😱

Structural insights into p300 regulation and #acetylation-dependent genome organisation
https://www.nature.com/articles/s41467-022-35375-2

- #alphafold model of p300 suggests that the TAZ2 domain is positioned over the p300 HAT active site

- #alphafold model in the presence of NUT AD shows that the TAZ2 domain is displaced from the HAT active site and suggest that the TAZ2 domain auto-inhibits the HAT domain

- domain truncation and #mutagenesis support the #computational #models !

Free #Covid tests available again -order online at https://www.covid.gov/tests

Want to follow the #neuroscience community on here? To follow to the 500+ people on the #neurodon list, use these steps:

1. Download the csv from here: https://docs.google.com/spreadsheets/d/1k3Q0LOewgIAJolbf-7XagK0twnpjeoyl2uLxR5U80vo/gviz/tq?tqx=out:csv&sheet=Importable+CSV
2. In Mastodon, hit Preferences > Import & Export > Import and upload the CSV. Wait a few minutes and you should get the entire list added to your follows.

To add yourself to the list, fill out this form: https://docs.google.com/forms/d/e/1FAIpQLSe1kBFA7AmziZUCgKYiHkHuKTpQEFu67dnTtUD8_NtZU_qVdQ/viewform

CC https://mastodon.social/@virati/109303734615646169

New platform, new #introduction

I'm a neuroAI researcher and neurotechnology consultant. I'm interested in the intersection of neuroscience and AI: what can AI teach us about how the brain works, and how can we use that knowledge to help people with neurological disorders thrive?

I've worked on this question in academia, in industry (Google, Meta) and in non-profits (Neuromatch). I write papers but some of my most high-impact writing is on my long-running blog, xcorr.net. I'm also the author of the good research code handbook, teaching students how to write code that doesn't bite back, goodresearch.dev.

#neuroscience #neuroAI

#Introduction

Hello #ScienceMastodon. We are the British Society for Developmental Biology.

We are here to immerse ourselves in the #DevBioMastodon universe and to keep you informed about the meetings we organise, the grants we give out and all the other good things that we do.

Need a place to send beginner students for microbiome-relevant computational biology training?

For the past 3 years, we have built a virtual course and symposium, attracting over 4,000 registrants from >80 countries.

All materials are freely available, and courses materials can be run/viewed on-demand.

Check it out, and if you like it, please share with your networks! https://isbscience.org/microbiome2022/

BTW, news.twtr.plus pretty much relays all the news accounts that are general news between the birb and here. It's even got the French news I follow.

Go to their main site and look for the account you want or just try to find it by doing a search for the birb @ plus the address of @news.twtr.plus. Super handy.

It unfortunately relays in batches but it's still nice to have news here.

Academia is competitive especially when there is free food around 😂

#academia #PhD #phdlife #science #xp @OpenAcademics @AcademicChatter

Tip I wish I'd learned earlier: follow #hashtags. Here's how:

1. Type your hashtag into search (e.g. #introduction )

2. Click the specific best hit in the results.

3. Click the little person with a + symbol on them to follow that hashtag as if it were an account.

Great way to find #newusers from the #twittermigration and posts relevant to your interests!

Do you use Wormbase / ParaSite?

Please help them secure future funding

#Celegans #nematode #science #funding

https://blog.wormbase.org/2022/12/12/wormbase-parasite-needs-your-help/

What would be a greater opportunity for my first post here other than announcing my first (first-author) paper? A thread:

Despite the increasing attention on the oral microbiome, until now we didn't have a good idea about how it evolves in the wild! In our new publication with Adrian Forsythe, @jfy133, Jaelle Brealey, Christina Warinner & Katerina Guschanski we investigate exactly this! 🦷🦠 https://doi.org/10.1093/molbev/msac263

#Drosophila #Advent Day15: A new genus with Scaptomyza pallida, a widespread species that breeds as a generalist on decaying plants https://link.springer.com/content/pdf/10.1007/BF00317362.pdf . Sister to the overly flamboyant Hawaiian Drosophila (#Idiomyia), the genus #Scaptomyza either invaded #Hawaii twice or evolved there and escaped three times https://academic.oup.com/genetics/article/209/1/1/5930949 . It is easy to sweep-net pallida from herbs or compost, and while these individuals may not look very pallid, other ones are more so http://www.drosophila.jp/jdd/class/030706/03070609.pdf

#egyptology #painting

An ancient Egyptian "masterpiece" painting of birds flying and perching within a verdant marsh is so detailed, modern researchers can tell exactly which species artisans illustrated more than 3,300 years ago.
https://www.livescience.com/realistic-bird-paintings-ancient-egypt

💥 Stop looking at your growing molecules, it’s time to play! Solve the latest of our #HTpuzzles and be the first of your colleagues to write the hidden word in the comments.

Screenshot and edit the image with your smartphone! Then save it and post the answer in the comments 😉

#science #sciencequiz #sciencemastodon #lifesciences #sciencepuzzle #sciencegame #games #puzzles #humantechnopole