New #podcast episode! Dr. Corey Hopkins discusses his career spanning industry and #academia, his #research developing and testing new compounds to treat diseases with unmet medical need, his life outside the lab, and more!
https://www.peoplebehindthescience.com/dr-corey-hopkins/
Thank you for a great conversation,
@Hopkins_Lab!
#chemistry #podcasts #science #STEM #scicomm #drugdiscovery #ScienceMastodon #biology
Power analyses should not be based on the effect you expect but on the smallest effect size of interest. You commonly hear people say power analysis is not possible because you don't know the effect size. But this is a (common) misunderstanding of what you are suposed to do in a power analysis. You plan for the effect you do not want to miss - not for a guess of what it might be. See https://online.ucpress.edu/collabra/article/8/1/33267/120491/Sample-Size-Justification
Stop the peer-review treadmill. I want to get off https://doi.org/10.1038/d41586-023-00403-8
Informative piece on the overburdened peer review system.
Happy to see discussion of preprint review: "Rebeccah Lijek ... directs her reviewing energies to preprints ... She loves being able to consider the science just on its merits, without judging whether a study is original enough to deserve publication by a specific journal. She finds the process more collegial and has made new connections and friends through it."
Yup -- it's true. This client has NO mental health coverage. My billing people say this is increasingly common.
In fact -- it gets worse. As my biller says:
"The only information they would provide is that she has no mental health benefits at all and that if she received treatment prior to the effective date of this coverage it would not be covered for 12 months due to being a pre-existing condition."
The plan is US Health Group (A Unitedhealthcare Company) underwritten by Freedom Life Insurance Company of America. They are formerly known as "UMR" and still appear this way in billing systems and their snail mail address.
Apparently a search of Maryland's ACA (Affordable Care Act) Health Connection website for useful insurance coverage prompts a flurry of texts and calls from random health insurance brokers looking to sell desperate people trash plans not on the state exchange. In this case some high speed sales script reading was involved and the client did not fully understand what was being purchased. This is not a stupid client.
There are so many problems here:
1) The original outrage of no mental health coverage.
2) The possibility that NO PRE-EXISTING CONDITION MIGHT BE COVERED. (I have no reason to assume that statement only applies to mental health pre-existing conditions. I don't know.).
3) That client contact data from Maryland Health Connection government website is available to brokers of possibly shady plans.
4) That United Health is actively supporting and has some ownership in a plan that certainly at least smells like a SCAM, although I'm sure it sold as extreme cut-rate no-frills insurance.
This needs to stop.
#psychology #insurance #mentalhealth #psychiatry #covid #socialwork
#healthadvocacy #aca #apa @psychology @socialwork
@psychotherapists @psychiatry #psychotherapy
#covidisnotover #telehealth
@SuprmomcatCathy @Neurogirl1976 @siderea @notes @dramypsyd
#marylandhealthconnection #marylandaca
#uhc #unitedhealthcare #ushealthgroup #UMR #freedomlifeinsurance
Just had a great discussion with an MDS task force on how best to define a tic. So, #Tourette world, how would _you_ define a tic?
In case you’re coming to Boston for @anpadirect and arrive the day before, consider visiting us for an informal pre-event at the @Brain_Circuits for two exciting talks from leading researchers in the field! 👇👇
@leaddbs @foxmdphd @shansiddiqi @neuromichael @IsaiahNeurology
---
RT @Brain_Circuits
Together with the @BSNNP1880,
the Center for Brain Circuit Therapeutics
is excited to host @ChristosGanos and @LUSCHERC for an evening …
https://twitter.com/Brain_Circuits/status/1620870914232696832
Thought today might be a good one to re-post something I'd put on another social network about #SolomonCarterFuller, often celebrated as the 1st Black psychiatrist, but whose place in #neurology and #neuroscience is underrecognized.
As a med student, Fuller attended a key event in the history of US neuropsychiatry: neurologist S. Weir Mitchell’s address to the AMPA (precursor to APA). Mitchell harshly critiqued the absence of a research program in asylum medicine. Asylums responded by setting up new labs; as autopsies were uncommon in the US compared to Europe, Fuller recognized that this new field presented more open opportunity to him as a Black MD, and came to lead a pathology lab at Westboro Hospital.
Like many US docs then, he sought more training in Europe. He studied German and in 1904 went to Munich, where he worked in Alzheimer's lab alongside Frederic #Lewy. He was treated more equitably there than in the US.
After his return to the US, Auguste D died in 1906 and #Alzheimer presented her case; that year Fuller presented one of the first accounts of neurofibrillary pathology to the AMPA. In 1912 Fuller published the 1st review of #AlzheimersDisease cases (including one of his own, the 9th overall) and the first English translation of Alzheimer's work.
In 1909, Fuller was invited to speak at #ClarkUniversity 20th anniversary; other invitees were a “little-known Viennese neurologist and his Swiss colleague” (Anne Harrington, Mind Fixers)—a turning point in US psychiatry. Fuller took interest in psychoanalysis & maintained correspondence w/ Jung, Meyer & Adler.
Fuller trained a cohort of Black psychiatrists, who mentored others. He led the #BostonUniversity dept of neurology for 5y but underpaid and untitled; when a white assistant prof was named chair ahead of him he went into private practice. His death was commemorated by James B Ayer: https://www.nejm.org/doi/full/10.1056/NEJM195401212500316
In addition to these scientific connections, Fuller enjoyed close ties with other important historical figures. His wife Meta was herself an important sculptor championed by Rodin & they were close with other leaders like W.E.B. DuBois & Paul Robeson.
Neurologists and neuroscientists should celebrate Fuller as our colleagues in #psychiatry do. I recommend Mary Kaplan's lively biography Where My Caravan Has Rested, including an oral history that Fuller dictated to his son, to all. #BlackHistory #BlackHistoryMonth #BlackInNeuro
Officially out now in Journal of Cognitive Neuroscience!
direct.mit.edu/jocn/article/3…
If you're interested in how individual differences in 🧠 brain organization differ across the hemispheres, check it out.
Great work by grad student Diana Perez! 🙌
and collaborators Ally Dworetsky, Rodrigo Braga, & Mark Beeman
Excited about this #Tourette treatment study extending the original work by Drs. Bàrbara Morera Màiquez & @jackson684. Median nerve stimulation #MNS improved tics during stimulation, but not via the originally proposed mechanism.
Peripheral nerve induction of inhibitory brain circuits to treat Tourette syndrome: A randomized crossover trial https://doi.org/10.1101/2023.02.01.23285304 #medRxiv @medrxivpreprint
We also completed an open-label follow-on study with an off-the-shelf TENS unit and #EMA ecological momentary assessments.
https://osf.io/n6f7q/
RT @bppebattaglia
one assumes revenue of about US$4,000 per subscription article, a conservative 30% profit margin and generous publication costs of US$600 per article then there remains a sizeable gap of about US$2,200 in non-publication costs. https://f1000research.com/articles/10-20
RT @shadbush
A simple algorithm to decide whether to use ChatGPT, based on my recent article (https://lnkd.in/eeZ5YNJh)
RT @Noahpinion
"We can't improve IQ, blah blah blah"
YES WE CAN, we do it every day, it's called "education".
https://journals.sagepub.com/doi/abs/10.1177/0956797618774253?journalCode=pssa
@NeuroSchnell @schoppik @NicoleCRust @brembs
As a reviewing editor, and as scientist and paper author, I have no idea who the “readership” is. Readers of one paper in a journal are extremely unlikely to want to read most papers from the same journal. Scientists read papers, not journals. A journal’s contents is a collection of misfits. There isn’t and there can’t be a coherent theme, as this would have to be so narrowly defined that it would, in essence, be personalised to each reader.
Scientists generally want their research to be openly accessible to the public.
So what's stopping them?
One study of Berkeley faculty (N = 479) found that 71% supported open access to research, yet only 18% of articles published by the group were open access.
"a journal having no cost to publish in was more important than having no cost to read"
via https://www.arl.org/wp-content/uploads/2023/01/2023.01.18-open-access-publishing-a-study-of-uc-berkeley-faculty-views-and-practices.pdf
#OpenScience #Science #AcademicChatter #SciComm @academicchatter
h/t @oatp
Sending this off to @biorxivpreprint very soon, but you can read it here first.
We've added GPT-3 revision suggestions to #manubot. The point where it suggested changes that fixed an incorrect reference to a mathematical symbol was 🤯.
Check out more at the link! #science #publishing #academia #ai #aiart
RT @foxmdphd
Awesome picture and paper showing the power of collaboration between psychiatry (@shansiddiqi) and neurology (@IsaiahNeurology) @Brain_Circuits @BrighamWomens https://twitter.com/brighamwomens/status/1616199007822352391
Non-profit journals as a solution to open science?
Publishers charge researchers incredible amounts to remove paywalls from their own papers...and make unbelievable profits from doing so. Several have an >30% profit margin.
Initiatives such as @PeerCommunityIn provide an alternative: open access, non-profit journals that are free to publish in.
https://peercommunityin.org/
https://peercommunityjournal.org/
#OpenScience #Science #AcademicChatter @academicchatter
Graph (2013): @alexh https://alexholcombe.wordpress.com/2013/01/09/scholarly-publishers-and-their-high-profits/
Husband, dad, Christian, neuroscientist, neuropsychiatrist. Speaking only for myself.