On #twitter I have four accounts for different topics. Twitter makes it easy to switch between them on the fly. Does that workflow make any sense at all with #mastodon?

@worldsendless Most phone clients support multiple accounts. On Tusky and its derivatives, it's a two-step process:
1. swipe from the left to open the navigation panel
2. tap the profile picture of your other account

Statuses also have a menu option to "open with" your other account. This saves you the trouble of navigating to it after switching.