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Dan Mucida boosted

"During systemic Salmonella Typhimurium (STm) infection germinal centers are absent, whereas extensive extrafollicular switched antibody responses are maintained. The mechanisms that underpin the absence of GC formation are incompletely understood. Here, we show that STm-induces a reversible disruption of niches within the splenic microenvironment, including the T and B cell compartments and the marginal zone."

cc @mucida @kevinng @BrodskyLab @victoralab

biorxiv.org/content/10.1101/20

Dan Mucida boosted

A small study in France showed a 10% vaccine failure rate in people who got a single dose of #mpox vaccine after an exposure event. People who developed the infection had mild symptoms. In Eurosurveillance. eurosurveillance.org/content/1

Last day in Twitter Dec31st? This is quickly becoming an alt-right platform. Yo estoy de salida

RT @wenzhang1120
Check out this Spotlight article by @danmucida and co for our recent findings on nociceptors and their roles in regulating the gut microbiome and mitigating intestinal inflammation: A triplex for intestinal protection: Neurons, microbes, and goblet cells cell.com/immunity/fulltext/S10

Let’s go 🇦🇷 x 🇲🇦 in the final!!

It feels like this will be my last month in Twitter. I hope to see you guys at Mastodon or anywhere not run by such a douche

RT @cyrilpedia
You can pick up this discussion with
@StearnsLab over on at

@StearnsLab

where @gregggonsalves

@gregggonsalves

is also sharing his thoughts on the topic twitter.com/StearnsLab/status/

Dan Mucida boosted

That's how you start an abstract:

"In the beginning it was simple: we injected a protein antigen and studied the immune responses against the purified protein. This elegant toolbox uncovered thousands of mechanisms via which immune cells are activated. However, when we consider immune responses against real infectious threats, this elegant simplification misses half of the story: the infectious agents are typically evolving orders-of-magnitude faster than we are."

cc @mucida @yilmaz

nature.com/articles/s41385-022

RT @andretrig
Dica pra quem tem dinheiro e está estressado c/a correria do Natal (presentes + ceia). Lembre-se das 280 mil pessoas em situação de rua (+38% desde 2019,segundo o Ipea), dos 65 milhões de negativados (SPC), dos 33 milhões que passam fome (Penssan).Se puder, ajude. Natal é isso!🌟

RT @evoespueblo
Merecida victoria, se siente con , Argentina Campeón del mundial @Qatar2022, Felicidades!!

Brazil played well, had most chances- Croatia had 1 shot on goal; yet we lost and this is why football is so popular and why we love it. I can't help but support mis hermanos Argentinos, even though they certainly celebrated Brazil's loss (as would Brazilian fans do) Vamos🇦🇷

RT @StearnsLab
From the perspective of a former study section chair, the suggested reviewing changes from @NIH look great. They are open for comments.

“Update on Simplifying Review Criteria: A Request for Information” nexus.od.nih.gov/all/2022/12/0

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