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che non mi ricordo il tag che avevo utilizzato la volta scorsa.
Oggi sono andato nuovamente dal tecnico IT a chiedere perché diamine dopo un MESE non mi abbia ancora messo la connessione Ethernet.
E mi dice, beh chiaro tu non hai incluso la data nello screenshot che mi hai inviato.

Ma almeno dimmelo, che te ne invio un altro. Porco boia io non posso lavorare per colpa di impediti che non riescono nemmeno a comunicare i problemi.
Io invece di lavorare devo stare qui dietro ai cazzi del tecnico IT.

Con i soldi che spendono a tenermi lì a lavorare ad un quarto della velocità potevano anche assumere un'altra persona a lavorare...

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@GustavinoBevilacqua
Vivo in questo appartamento da un paio di mesi ed ho dovuto mettere mano ad un paio di cose.
Non so chi cazzo abbia fatto i lavori dato che è dipinto di merda; però l'elettricista era un vero criminale.
La casa è vecchia ed ha un impianto le cui prese elettriche manco esistono più; ci sono dei segni di ammodernamento ma invece di rifare l'impianto ci si sono attaccati sopra ed hanno aggiunto cose (tutto dietro un interruttore generale a fusibile).

Beh, per ora ho trovato una presa con terra e fase invertite ed un'altra avvitata con autofilettanti direttamente nel muro che ovviamente si sono staccate
Non vedo l'ora di trovare un trapano...

Software for quantum mechanics which implements modern methodologies.
Written in Fortran to run faster.
Stable and maintained for 20 years.
No parallelization and no GPU support.
"The software is meant to be run on personal computers"

Are you kidding me?

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@GustavinoBevilacqua Yep, it's all one file for easy transport. For measuring speed, I find it handy to put a long ruler beside the thing I'm measuring and then take video of it in action. Then I can count the number of frames it takes to go some distance and calculate the speed.

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#2687 Division Notation 

Science tip: Scientists hardly ever use the two-dot division sign, and when they do it often doesn't even mean division, but they still get REALLY mad when you repurpose it to write stuff like SALE! ALL SHOES 30÷ OFF!
xkcd.com/2687/

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Before you marry a person, you should first make them use a computer with a slow Internet connection to see who they really are.

Che poi 35 k quando va bene; perché sennò non si spiega che per 22 MB ci sta mettendo quasi un'ora...

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Evviva! Oggi è venuto il tecnico ed ha fatto un altro screenshot al mio indirizzo Mac.
Dice che a breve mi metterà la connessione Ethernet!

Intanto io è tre settimane che vado così

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Text might be the most neglected part of #dataviz. We talk a lot about how the right chart type and colors can improve visualizations – but not enough about how to use words well.

So I wrote about that in my latest article: blog.datawrapper.de/text-in-da

@GustavinoBevilacqua ora puoi mostrarci le lattine di birra che bevi in tutta la loro rotonda grandiosità!

A Clever device to photograph tins

blog.openfoodfacts.org/en/news

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I wish there was a way to subscribe to people's posts and not their retoots

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@rastinza io non sono contro la violenza, ma mi è molto chiara la differenza tra violenza e oppressione. il tornaconto personale non può giustificare l'oppressione, e in questo non vedo come la specie di apprtenenza possa fare alcuna differenza. @Fittoveg

@aleff e in generale, spero tu non prenda questo thread come un processo o simili, non è minimamente nelle mie intenzioni. qui, con tutti i limiti del mezzo, quello che tento di fare è di dibattere e crescere :)


Some information about how new medicines are made by a guy who read a bit about it.

Most medicines target a particular protein in the human body.
The objective is to have something that interacts with the protein so that the function of the protein is altered.
Many things can be used to alter those mechanisms, such as small molecules, other proteins, antibodies and other things.

These things hopefully go nearby the protein of interest and modify its shape or block some part of it.

It is difficult to find one such thing that modifies the function of the protein in the desired way that is expected to cure the disease.
It's even more difficult to find one who does not interact with other proteins and causes toxic side effects.

I'll quickly outline some methodologies used to find small molecules that can act as medicines.
Small molecules are molecules made up of atoms with a contained dimension, much smaller than the common protein.

One very simple way to find such a molecule is to test a lot of different molecules with the protein in a laboratory and observing if something good happens.
This methodology is pretty good since it requires no prior knowledge about the protein nor about the molecules you're testing.
This procedure however also has some downsides: you need to obtain all the molecules you need to test and you need either a lot of people testing them or some specialized machinery.
This is of course very expensive.
Moreover, if none of the molecules you were able to obtain are good for curing the disease, you just spent a lot of money and gained little information about how to cure the disease.

This first methodology is very widespread in the big pharma industry, since they have the means to sustain the costs of a potentially fruitless expense.
It is difficult to find this kind of methodologies used in universities and research institutions, due to more limited budget.

Alright, this was a first quick introduction to the theme, if you're interested I can write a bit more; trying to keep it simple.
Let me know what you could be interested in knowing.

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Hello World!

GIMP project now gets a new official Mastodon account! 🥳

We can see the info leaked somehow (we had not announced it and already got 150+ followers in 2 days) 😂.

GIMP news will be coming here too, from now on!

Note: illustration by Aryeom (edited from her original video "What is the Fediverse?"), licensed under Creative Commons Attribution-ShareAlike 4.0 International.

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