Albert Cardona @albertcardona@qoto.org
- Personal website
- https://albert.rierol.net
How does the brain work? Someday, we'll figure it out.
Group Leader, MRC LMB, and Professor, University of Cambridge, UK.
#neuroscience #Drosophila #TrakEM2 #FijiSc #CATMAID #connectomics #vEM
Born at 335 ppm.
Brains, signal processing, software and entomology: there will be bugs.
Joined Oct 2022
Albert Cardona
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Hello Mastodon community! We're happy to be here and share updates on all things Framework. If you haven't heard of us yet, take a peek at https://frame.work
Albert Cardona
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A Painted Lady (Vanessa cardui) in honour of today's #MastodonMigration event. These nomadic butterflies embark on a multi-generational odyssey between tropical Africa and northern Europe each year - the longest known migration of any butterfly!
#butterfly #butterflies #PaintedLady #insect #insects #Lepidoptera #entomology #nature #wildlife #britishwildlife #britishnature #ukwildlife #ecology #migration #AnimalMigration
On dead ants ... their mandibles and bodies can endure a lot. Here is another unidentified dead ant, mandibles clasping onto the leg of a masked bee (who knew ants and bees battle?). The dead ant served as a natural marker for this one particular bee, which I was able to recognize over the course of multiple days on the same mint flowers.
Hylaeus modestus (a masked bee) plus unknown ant, on mint flowers https://www.inaturalist.org/observations/30098847
And differences in size are also the norm. Not only among ant castes of the same species, but particularly among different species! Here we see a desert ant (a relatively large ant for Europe) carrying a tiny dead one still clasping its mandibles on its antenna, marching on unfazed at full speed among the pebbles of a Croatian beach.
Cataglyphis nodus (large ant) and an unidentified tiny dead ant attached to its right antenna. https://www.inaturalist.org/observations/92084232
Differences between males and females are the norm among ants. This male ant is tiny at 3 millimetres long. For the longest time, I had not the foggiest idea what this was other than a wasp-like animal. Thanks to the iNaturalist community it was identified.
Male ants are a rare sight, emerging only at the right season and only for a brief period of time. It is said that most die shortly after mating.
Stigmatomma sp, possibly S. denticulatum. https://www.inaturalist.org/observations/88809662
Have you ever seen ants mating?
Right on the windshield of our car, this past summer. The male is indeed tiny. Crummy photo, was as spontaneous and unplanned as it gets: at a traffic light!
Lasius sp. (likely but unconfirmed) https://www.inaturalist.org/observations/125201675 There are more photos at the #iNaturalist entry.
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#Introduction I'm a prof in cognitive neuroscience at University College London. My research group studies spatial cognition in range of areas and methods from single-unit recordings in rodents to self-reports in humans.
Here's a painting of my brain from 20 years ago. I still do a lot of fMRI
Albert Cardona
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Is this how you toot? 📯
I'm Lauren, Ph.D, former journal editor (PLOS Bio), podcast host (Bio Eats World), and sci comm specialist. I just started my own company (LR Bio) to help biotechs tell their science stories.
I'm always down to delve into the mysteries inherent in the vastness of biology!
Albert Cardona
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Hi everyone--I'm Ami and I'm part of the #TwitterMigration. Still figuring this place out but it seems friendly, which is both delightful and disconcerting. I post about books, politics, repro rights, witches, Jewish stuff, and my dog. I'll try not to knock things over but I can't promise anything. #Introduction
Albert Cardona
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Happy It's #flyday Friday! Why is 11/18 fly day? Because this is when good old w1118 was discovered! Hear it from the man himself, Gerry Rubin:
Albert Cardona
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Albert Cardona
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Unbelievable, multiview-reconstruction & BigStitcher have finally lost their Imglib1-dependency! And all processing is now virtual thus scaling to larger volumes ... @herrsaalfeld
https://github.com/preibischlab/multiview-reconstruction
https://github.com/PreibischLab/BigStitcher
Albert Cardona
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genetic model system bugs
Happy Fly Day to all who celebrate!
Albert Cardona
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My group is recruiting Flatiron Research Fellows!
Our interests include: theory development + data analysis with neural manifolds, and theory of neural networks.
Neuro interactions with Flatiron CCN, NYU Center for Neural Science, Machine Learning interactions with NYU Center for Data Science.
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Hi everyone. We’re #Co_Biologists, a not-for-profit #publisher dedicated to inspiring the #biology community:
- We publish five #journals: @Dev_journal @J_Cell_Sci @J_Exp_Biol @DMM_Journal & @BiologyOpen
- We facilitate scientific #meetings & provide #grants for #researchers
- We run three #community sites: @the_node @preLights @focalplane_jcs
- We are committed to #OpenAccess
- We have initiatives to support early-career researchers #ECRs
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#Introduction Part 2:
My lab invented the open-source software CellProfiler and the imaging assay Cell Painting and we now focus on using our machine learning and deep learning skills for image-based profiling, to accelerate drug discovery and functional genomics. Our research led to the founding of Recursion, a clinical-stage techbio powered largely by the information in cell images.
#CellProfiler #DrugDiscovery #TechBio #RXRX #MachineLearning #DeepLearning
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I recommend this article "DEI conversations: more than a box-ticking exercise" by @@felicitydavis2@twitter.com
https://www.nature.com/articles/s41580-022-00565-9
I hope we can take her message to heart of *not* being incremental in our DEI work, just as we don't want to be incremental in our research. It reminded me of this post from @mekkaokereke https://fediscience.org/@mekkaokereke@mastodon.cloud/109359450386255369
about finding the write framing for change that fits an organization's culture -- this seemed like a convincing framework for researchers!
Albert Cardona
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#WomenInScience are recommended to 'not apologize a lot'.
A lot of issues would resolve themselves if #MenInScience apologized for their mistakes more.
Recognizing that you made a mistake, or that you don't know something, or behaved in a poor fashion and apologizing is not a problem. It tells me that you have the critical capability to introspect and understand what impact you have on others. It tells me that you care about doing #science right, that you want to learn.
Albert Cardona
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... and this cheat sheet on curve fitting, by XKCD (on Masto?)...
https://m.xkcd.com/2048/
When a GABAergic neuron synapses onto the axon of a sensory neuron, what happens?
Turns out, in the proprioceptors of the locust leg (chordotonal somatosensory neurons), "All the available evidence indicates that the inputs that occur during walking are depolarizing, inhibitory, synaptic inputs."
Depolarizing, inhibitory. How's that possible? Depolarizing because of where the resting potential of the axon is (which is different than the dendrite's), and the particularities of the GABA receptor on the receiving axons. Inhibitory because the depolarization is subthreshold, reducing the membrane voltage potential and, therefore, reducing neurotransmitter release when a spike arrives.
What is this good for? Implementing an efference copy signal: "The rhythmic depolarization at different phases of the step cycle in different sensory neurons may represent a predictive action of the CNS when generating a motor pattern." That is, predicting when the proprioceptor will fire, and by how much, as a function of the self-induced motion. So this signal is subtracted in order to be able to measure (and react to appropriately) any unexpected signal (such as the leg skidding or hitting a rock).
Wolf and Burrows, 1995. "Proprioceptive sensory neurons of a locust leg receive rhythmic presynpatic inhibition during walking" https://www.jneurosci.org/content/15/8/5623.short
Burrows and Matheson, 1994. "A presynaptic gain control mechanism among sensory neurons of a locust leg proprioceptor" https://www.jneurosci.org/content/14/1/272.short
- Personal website
- https://albert.rierol.net
How does the brain work? Someday, we'll figure it out.
Group Leader, MRC LMB, and Professor, University of Cambridge, UK.
#neuroscience #Drosophila #TrakEM2 #FijiSc #CATMAID #connectomics #vEM
Born at 335 ppm.
Brains, signal processing, software and entomology: there will be bugs.
Joined Oct 2022
