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Fully GPU-Accelerated Immersed Boundary Method for Fluid-Structure Interaction in Complex Cardiac Models arxiv.org/abs/2503.22695

Fully GPU-Accelerated Immersed Boundary Method for Fluid-Structure Interaction in Complex Cardiac Models

Fluid-structure interaction (FSI) plays a crucial role in cardiac mechanics, where the strong coupling between fluid flow and deformable structures presents significant computational challenges. The immersed boundary (IB) method efficiently handles large deformations and contact without requiring mesh regeneration. However, solving complex FSI problems demands high computational efficiency, making GPU acceleration essential to leverage massive parallelism, high throughput, and memory bandwidth. We present a fully GPU-accelerated algorithm for the IB method to solve FSI problems in complex cardiac models. The Navier-Stokes equations are discretized using the finite difference method, while the finite element method is employed for structural mechanics. Traditionally, IB methods are not GPU-friendly due to irregular memory access and limited parallelism. The novelty of this work lies in eliminating sparse matrix storage and operations entirely, significantly improving memory access efficiency and fully utilizing GPU computational capability. Additionally, the structural materials can be modeled using general hyperelastic constitutive laws, including fiber-reinforced anisotropic biological tissues such as the Holzapfel-Ogden (HO) model. Furthermore, a combined geometric multigrid solver is used to accelerate the convergence. The full FSI system, consisting of millions of degrees of freedom, achieves a per-timestep computation time of just 0.1 seconds. We conduct FSI simulations of the left ventricle, mitral valve, and aortic valve, achieving results with high consistency. Compared to single-core CPU computations, our fully GPU-accelerated approach delivers speedups exceeding 100 times.

arXiv.org

Nonzero RMS Magnetoresistance Yielding Control Space Partition of CrTe2 Monolayer arxiv.org/abs/2503.22750

Nonzero RMS Magnetoresistance Yielding Control Space Partition of CrTe2 Monolayer

The study of magnetic phenomena in low-dimensional systems has largely explored after the discovery of two-dimensional (2D) magnetic materials, such as CrI3 and Cr2Ge2Te6 in 2017. These materials presents intrinsic magnetic order, overcoming the limitations predicted by the Mermin-Wagner theorem, due to magnetic crystalline anisotropy energy. Among these, CrTe2, a van der Waals 2D magnet, has gather significant interest due to its in-plane anisotropic magnetoresistance (AMR) and high Curie temperature. This study investigates the magnetic field-regulated resistance of CrTe2 monolayers in the context of spintronics applications. Utilizing the zigzag-ordered parameters obtained from prior simulations, we examine how external magnetic fields influence resistance states and control the ON/OFF state of nano-devices. The analysis demonstrates that specific magnetic field configurations, particularly those in the form of (0, 0, Bz), which is out-of-plane directed field, gives a non-zero root mean square resistance, indicating a functional ON state. This provides a novel method for magnetically controlled current regulation in spintronic devices. The experimental results also reveal an interesting spin-flop transition in CrTe2 under a z-directed magnetic field, leading to y-directional magnetization. This phenomenon, combined with the material's robust magnetic properties, positions CrTe2 as a promising candidate for next-generation memory and logic devices. By advancing the understanding of magnetic field manipulation in 2D magnetic materials, this research opens new pathways in the development of energy-efficient spintronics technology.

arXiv.org

Crossover between the zeptosecond and attosecond physics arxiv.org/abs/2503.22766

Crossover between the zeptosecond and attosecond physics

Nuclear orbiting resonances have been revealed at the sub-barrier energies as an atomic phenomenon by means of x-ray spectroscopy experiments. This interpretation is supported by several phenomenological models and theoretical estimates of the nuclear orbiting timescale and cross-section, inelastic scattering cross section including both nuclear and Coulomb excitation, and the Wigner-Smith time delay. We demonstrate that a multi-photon exchange during nuclear orbiting is responsible for an atomic excitation. Furthermore, proximity of the projectile and target nucleus during the nuclear orbiting modifies the effective charge of the projectile. Even though this orbiting induced excitation is triggered in zeptoseconds, it can still be observed in the attosecond time scale because of the Wigner-Smith time delay inherent to autoionization. Thus, we demonstrate the crossover between the zeptosecond and attosecond time scales which are native to nuclear and atomic physics, respectively. Markedly, this crossover may be the reason for x-ray production from ultra short nuclear processes ($\leq 10^{-21}$ sec). This explanation is likely to resolve the fission time scale anomaly and can stimulate cross-disciplinary research ranging from solid state to high-energy physics.

arXiv.org

Correlative Symmetric Index: An alternative mathematical evaluation for beam profile symmetry arxiv.org/abs/2503.22820

Correlative Symmetric Index: An alternative mathematical evaluation for beam profile symmetry

This work assess the accuracy of standard profile beam symmetry metrics used in radiotherapy quality assurance and compare them to the proposed correlative symmetric index metric and Structural similarity index. The objective is to propose a new method based on cross correlation, named correlative symmetric index, that we show is less susceptible to noise than traditional methods. In addition, a supplemental method called Structural Similarity Index is presented.Simulations of non symmetric beams with similar left and right areas were used to compare the effectiveness of quantifying beam symmetry through proposed and standard methods. To assess each metric dependence on noise, an assessment was performed on all metrics using a noisy, simulated, non symmetric beam profile. A comparison of standard and proposed methods was also performed to characterize beam symmetry of roughly symmetric beam profiles measures at different depths in a water tank.In quantifying beam symmetry, the proposed correlative index metric and Structural Similarity Index method resulted in values 0.387, 0.5401, respectively for the non symmetric noisy scenario. More traditional approaches of PDQ and area based symmetry resulted in values of 0.312 and 0.400, respectively, for the non symmetric noisy scenario. The corresponding percentage change between the non symmetric no noise and the non symmetric with noise for the Point Difference Quotient, area based symmetric value, Structural Similarity Index Measurement, and Correlative symmetric index were 0.111, 0.056, 0.1625, 0.008, respectively. For the clinical measured symmetric profiles all methods achieved values above 0.9. Comparisons of quantitative and qualitative metrics demonstrate that the proposed correlative symmetry index method outperforms both the pointwise and area based symmetric metrics for when beam profiles are noisy.

arXiv.org

SeisRDT: Latent Diffusion Model Based On Representation Learning For Seismic Data Interpolation And Reconstruction arxiv.org/abs/2503.21791

SeisRDT: Latent Diffusion Model Based On Representation Learning For Seismic Data Interpolation And Reconstruction

Due to limitations such as geographic, physical, or economic factors, collected seismic data often have missing traces. Traditional seismic data reconstruction methods face the challenge of selecting numerous empirical parameters and struggle to handle large-scale continuous missing traces. With the advancement of deep learning, various diffusion models have demonstrated strong reconstruction capabilities. However, these UNet-based diffusion models require significant computational resources and struggle to learn the correlation between different traces in seismic data. To address the complex and irregular missing situations in seismic data, we propose a latent diffusion transformer utilizing representation learning for seismic data reconstruction. By employing a mask modeling scheme based on representation learning, the representation module uses the token sequence of known data to infer the token sequence of unknown data, enabling the reconstructed data from the diffusion model to have a more consistent data distribution and better correlation and accuracy with the known data. We propose the Representation Diffusion Transformer architecture, and a relative positional bias is added when calculating attention, enabling the diffusion model to achieve global modeling capability for seismic data. Using a pre-trained data compression model compresses the training and inference processes of the diffusion model into a latent space, which, compared to other diffusion model-based reconstruction methods, reduces computational and inference costs. Reconstruction experiments on field and synthetic datasets indicate that our method achieves higher reconstruction accuracy than existing methods and can handle various complex missing scenarios.

arXiv.org

Impact of Oxygen on DNA Damage Distribution in 3D Genome and Its Correlation to Oxygen Enhancement Ratio under High LET Irradiation arxiv.org/abs/2503.21837

Impact of Oxygen on DNA Damage Distribution in 3D Genome and Its Correlation to Oxygen Enhancement Ratio under High LET Irradiation

The variation of the oxygen enhancement ratio (OER) across different values of Linear Energy Transfer (LET) currently lacks a comprehensive mechanistic interpretation and a mechanistic model. Our earlier research revealed a significant correlation between the distribution of double-strand breaks (DSBs) within the 3D genome and radiation-induced cell death, which offers valuable insights into the oxygen effect. In this study, we formulate a model where the reaction of oxygen is represented as the probability of inducing DNA strand breaks. Then it is integrated into a track-structure Monte Carlo simulation to investigate the impact of oxygen on the spatial distribution of DSBs within the 3D genome. Results show that the incidence ratios of clustered DSBs in a single topologically associating domain (TAD) (case 2) and DSBs in frequently-interacting TADs (case 3) under aerobic and hypoxic conditions closely align with the trend of the OER of cell survival across various LET values. By utilizing the parameters derived from our previous study, we calculate the OER values related to cell survival. Our OER curves exhibit good correspondence with experimental data. This study provides a potentially mechanistic explanation for the changes in OER across different LET levels. High-LET irradiation leads to dense ionization events, resulting in an overabundance of lesions that readily induce case 2 and case 3. The probabilities of cell death associated with case 2 and case 3 are substantially higher than other damage patterns. This may contribute to the main mechanism governing the variation of OER for high LET. Our study further underscores the importance of the DSB distribution within the 3D genome in the context of radiation-induced cell death. This study also provides valuable reference points for establishing a mechanistic model of OER.

arXiv.org

Impact of freestream turbulence and thrust coefficient on wind turbine-generated wakes arxiv.org/abs/2503.21903

Impact of freestream turbulence and thrust coefficient on wind turbine-generated wakes

This study investigates how variations in freestream turbulence (FST) and the thrust coefficient ($C_T$) influence wind turbine wakes. Wakes generated at $C_T \in \{0.5, 0.7,0.9\}$ are exposed to turbulent inflows with varying FST intensity ($1\% \lesssim TI_{\infty} \lesssim 11\%$) and integral length scale ($0.1 \lesssim \mathcal{L}_x/D \lesssim 2$, $D$ is the rotor diameter). For high-$TI_{\infty}$ inflows, a flow region within the wake is observed several diameters downstream, where a mean momentum deficit persists despite the turbulence intensity having already homogenised with the freestream, challenging traditional wake definitions. A ``turning point'' in the mean wake width evolution is identified, beyond which wakes spread at slower rates. Near-field ($x/D \lesssim 7$) wake growth rate increases with higher $TI_{\infty}$ and $C_T$, while far-field ($x/D \gtrsim 15$) wake growth rate decreases with higher $TI_{\infty}$ -- a finding with profound implications for wind turbine wake modelling that also bridges the gap with entrainment behaviours observed in bluff and porous body wakes exposed to FST. Increasing $\mathcal{L}_x$ delays wake recovery onset and reduces the mean wake width, with minimal effect on the spreading rate. Both $C_T$ and FST influence high- and low-frequency wake dynamics, with varying contributions in the near and far fields. For low-$TI_{\infty}$ and small-$\mathcal{L}_x$ inflows, wake meandering is minimal, sensitive to $C_T$, and appears to be triggered by shear layer instabilities. Wake meandering is enhanced for high-$TI_{\infty}$ and large-$\mathcal{L}_x$ inflows and is dominated by background turbulence. This emphasises the complex role of FST integral length scale: while increasing $\mathcal{L}_x$ amplifies meandering, it does not necessarily translate to larger mean wake width due to the concurrent suppression of entrainment rate.

arXiv.org

Universal energy cascade in homogeneous binary fluid turbulence: A direct comparison of different exact relations arxiv.org/abs/2503.21926

Universal energy cascade in homogeneous binary fluid turbulence: A direct comparison of different exact relations

Below critical temperature, turbulence prevents the spontaneous phase separation of binary mixtures, resulting in a phase arrested state of emulsion which is of significant interest for scientific and industrial applications. The current work is an extensive continuation of our initial theoretical investigation into the nature and universality of associated energy cascade (Pan and Banerjee, PRE, 2022). In addition to the previously derived divergence and correlator forms of the exact relations, a Banerjee-Galtier type divergence-free form of the exact relation is derived under the explicit assumption of homogeneity. By performing three-dimensional direct numerical simulations with up to $1024^3$ grid points, we show that the sum of the kinetic and active energy associates a Kolmogorov-like universal cascade with constant flux rate across inertial scales. Despite term-by-term deviations, the cascade rates computed from all three exact laws show excellent agreement, thereby confirming the equivalence of different exact relations and hence the feasibility of determining the net cascade rate from any of the three formulations. Notably, the two dominant flux rates of the divergence form are found to cross each other roughly at the domain size, which also serves as an infrared cut-off for the inverse cascade of the small scale active energy. This behaviour is phenomenologically justified based on the interplay between the flow and surface dynamics of a phase arrested binary fluid.

arXiv.org

Supersonic wave propagation in active non-Hermitian acoustic metamaterials arxiv.org/abs/2503.21933

Supersonic wave propagation in active non-Hermitian acoustic metamaterials

Obtaining a group velocity higher than the speed of sound in a waveguide is a challenging task in acoustic wave engineering. Even more challenging is to achieve this velocity increase without any intervention with the waveguide profile, such as narrowing or widening, and particularly without interfering with the passage by flexible inclusions, either passive or active. Here, we approach this problem by invoking concepts from non- Hermitian physics, and imposing them using active elements that are smoothly sealed within the waveguide wall. In a real-time feedback operation, the elements induce local pressure gain and loss, as well as non-local pressure integration couplings. We employ a dedicated balancing between the control parameters, derived from lattice theory and adjusted to the waveguide system, to drive the dynamics into a stable parity-time-symmetric regime. We demonstrate the accelerated propagation of a wave packet both numerically and experimentally in an air-filled waveguide and discuss the trade-off between stabilization and the achievable velocity increase. Our work prepares the grounds for advanced forms of wave transmission in continuous media, enabled by short and long range active couplings, created via embedded real-time feedback control.

arXiv.org

When Cubic Law and Darcy Fail: Correcting Model Misspecification in Fracture Conductivities arxiv.org/abs/2503.20788

When Cubic Law and Darcy Fail: Correcting Model Misspecification in Fracture Conductivities

Uncertainties in the subsurface challenge reliable leakage risk assessments and long-term integrity of CO2 storage. Fault zones, characterised by multi-scale heterogeneities, are critical pathways for leakage and suffer from significant data uncertainties due to unresolved features. Understanding the multi-scale uncertainties in estimating fracture network conductivity is essential for mitigating leakage risks and ensuring reliable modelling of upscaled fault leakage rates. However, current models fail to capture all fault zone heterogeneity, particularly fracture surface roughness effects on fluid migration. Simplified assumptions, such as the Cubic Law based on mechanical aperture measurements, lead to erroneous models known as model misspecifications and introduce modelling uncertainty in leakage predictions. Here, we develop an AI-driven framework to address data uncertainties and correct model misspecifications in estimating fracture conductivities. By automatically integrating small-scale uncertainties, including fracture surface roughness, and leveraging their interactions across scales, we improve upon traditional empirical corrections. We combine physics-based constraints with adaptive, data-driven and geometric corrections to infer the hydraulic aperture governing fluid flow in fractures with varying roughness. This approach generates reliable local permeability maps that account for roughness effects and discrepancies between mechanical and hydraulic apertures, accurately reflecting overall fracture conductivity. By propagating uncertainties from individual fractures to network scales, our approach will support robust calibration of conductivity ranges for fault leakage sensitivity analyses, not only resolving uncertainties in fracture-scale modelling but also enabling efficient integration into larger-scale simulations to enhance predictions for subsurface CO2 storage.

arXiv.org
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