Thiago Carvalho @cyrilpedia@qoto.org
I've worked on all of science, from B cells to T cells.
https://fellowsherpa.com
Joined Nov 2022
From Oliver Sacks, "River of Consciousness".
#Books #Bookshelf #BookClub #consciousness #SciComm #readerlife #bookstodon
What a great cover.
From the NYT obit for artist Bruce McCall
'GSDM (the gene encoding gasdermin) and GSDM-like genes are evolutionarily ancient and have been identified across a wide range of animal and nonanimal species, including fungi and bacteria.'
https://journals.plos.org/plosbiology/article?id=10.1371/journal.pbio.3002103
'These distinct roles for EZH2 in promoting prostate cancer progression, metastasis, and AR independence raise the possibility that it could be a potential therapeutic target in advanced disease.'
https://journals.plos.org/plosbiology/article?id=10.1371/journal.pbio.3002038
'Writing in Nature, Krishna et al.2 show that malignant gliomas can grow by modifying brain circuitry, thus taking cognitive function away from their host and ultimately leading to death. These insights might lead to fundamentally new approaches to glioma treatment and provide a means of limiting cognitive decline in affected individuals.'
'C closed his eyes briefly. “Have you any idea how fucking rhetorical that was?”
This time, Howard didn’t reply.'
'Marsella, capital de la Provenza, es una ciudad de ciudades, la más antigua y la más diversa de Francia. Una muñeca rusa que entraña tantas posibilidades como ambición tenga cada visitante.'
'Our findings demonstrate that developmental bias in fly wings predicts evolvability and macroevolutionary trajectories on a much greater scale than previously appreciated but also suggest that causal explanations for such alignments may go beyond simple constraint hypotheses.'
#Evolution #EvoDevo
Etching on copper by @madparreira
#printmaking #art #print #printmaker #etching #handmade #prints #artgallery #artmastodon
https://madalenaparreira.com/Etchings
Humble beginnings.
(from Robert Kohler's very readable history of drosophila research, Lords of the Fly)
#ScienceCommunication #SciComm #HistoryofScience #Drosophila #books #bookshelf #bookstagram
'Recently, a proof-of-concept study demonstrated the idea of “humanizing” zebrafish. Simply, introduced hematopoietic stem cells and human monocytes/macrophages into larval zebrafish retained tissue specific function.'
'In any case, it is remarkable that senolysis of a small fraction of senescent osteocytes may account for the robust bone-protective effect, further supporting the importance of osteocytes for bone metabolism and skeletal health. Given their crucial role in orchestrating bone remodeling and their high degree of connection, these few senescent osteocytes may be sufficient to cause functional chaos through cellular miscommunication.'
Relief etchings on copper, Madalena Parreira.
#Print #Printmaking #Etching #handmade #artgallery #artmastodon
'As cancer formation, growth, and progression subvert and repurpose mechanisms of development and regeneration, the nervous system may be implicated in all aspects of cancer pathophysiology. Reciprocally, cancer and cancer therapies can influence and remodel the nervous system, contributing to pathological feedback loops that not only yield neurological dysfunction but can also drive malignancy.'
A useful rule of thumb is 'if Thomas Boehm is giving a seminar in your general geographic area, go'.
Oded Rechavi: “There are a few open questions that are very big, like can epigenetic inheritance, which is typically transient, affect the process of evolution.”
#SciComm #EMBOPodcast #Epigenetics #SciencePodcast #ThrowbackThursday
I've worked on all of science, from B cells to T cells.
https://fellowsherpa.com
Joined Nov 2022
