If you like the #handmade #ceramics #stoneware from @hunchbacksociety and are in Lisbon today & tomorrow (Friday and Saturday).
FEIRA DA FRUTEIRA
Curadoria de FELIPA ALMEIDA
26 & 27 Maio
Post hoc analysis of data from three phase III trials of atezolizumab in advanced non–small cell lung cancer finds an association between adverse immune reactions and response to treatment.
#cancerresearch #immunotherapy
“She loved to drink, on doctor’s orders of course, and would sit for hours absorbing whiskey-and-soda and Al’s talk. He was wonderful with her; he would start with palmistry, and without her knowing it end with Das Kapital.”
#Books #FoodWriting #Bookshelf #BookClub #Reader #MFKFisher #bookstodon
'We found that the follicular dendritic cell network was smaller in aged mice. Furthermore, the TFH cells that are normally localized within the light zone were instead dispersed throughout the GC in aged mice (Fig. 1), owing to enhanced expression of CXCR4 (a CXCL12 receptor) that directed the TFH cells to the CXCL12-rich dark zone.'
#Immunology #GerminalCenter
Candlestick holder by @hunchbacksociety
#ceramics #stoneware #ceramic #art #handmade #artgallery #artmastodon
FDA approves a fecal microbiota pill for recurrent C. diff infection. My latest #ClinicalPipeline column for Nature Medicine. #Medicine #SciComm #ScienceCommunication #Microbiology https://www.nature.com/articles/d41591-023-00046-2
Joaquim Maria Machado de Assis is one of the greatest novelists ever (though I cant speak to the quality of the translations):
"I had to force myself to finish it. For years, I didn’t pick up another one of his books. When at last I did, I was bewildered by my initial impression. Where first I had been bored, I was now enthralled. Where I had seen salon chitchat, I now saw the musings of genius. I wanted more."
https://www.nytimes.com/2023/05/22/books/review/machado-de-assis-dom-casmurro.html
'So you want to be a writer...'
A good list by Helen Pearson - in Kaaren Janssen & Richard Sever's collection of essays on "Career Options for Biomedical Scientists" (CSH Press).
Amen to #3.
'Gullotta et al. explore ischemic stroke in aged mice and elderly people, identifying age-related alterations in stroke-induced granulopoiesis and characterizing a pathogenic signature of circulating neutrophils that is linked to poorer outcomes. Reversing the neutrophil phenotype in old mice by transfer of young hematopoietic cells improved tissue repair and regeneration after stroke'
Works in progress @hunchbacksociety
#ceramics #stoneware #artgallery #handmade #ceramic #artmastodon
“The carrion birds sat about the topmost corners of the houses with their wings outstretched in attitudes of exhortation like dark little bishops.”
#CormacMcCarthy #BloodMeridian #Books #Bookshelf #ClassicBooks #bookstodon
'Comparison of Xenopus species that evolved through polyploidization revealed that metabolic differences emerged during development when cell size scaled with genome size. Thus, ploidy affects metabolism by altering the cell surface area to volume ratio in a multicellular organism.'
https://www.cell.com/current-biology/fulltext/S0960-9822(23)00391-3
In which @madparreira made a fully wearable dress out of paper - and then printed it!
Another entry in our 'not all good wines are Portuguese' series, courtesy of my gracious host in Nice, @miguelgf
"To enable detection of which cells upregulate MHC pathways in vivo, we generated two novel MHC I and MHC II reporter mouse lines that express tdTomato when these pathways are activated, and used these lines to define their incidence and transcriptional characteristics in two mouse models of inflammatory demyelination."
#Neuroimmunology
I've worked on all of science, from B cells to T cells.
https://fellowsherpa.com