Thiago Carvalho @cyrilpedia@qoto.org
I've worked on all of science, from B cells to T cells.
https://fellowsherpa.com
Joined Nov 2022
If you will be in Lisbon on June 16th
'Here, we show that yeast paralogous genes are more divergent in transcription than in translation. We explore two causal mechanisms for this predominance of transcriptional divergence: an evolutionary trade-off between the precision and economy of gene expression and a larger mutational target size for transcription.'
https://journals.plos.org/plosgenetics/article?id=10.1371/journal.pgen.1010756
"To watch Bruce Springsteen step onto a stage in New Jersey is to watch Moses walk to the edge of the Red Sea, so confident in his ability to perform a miracle, to carry his people to the Promised Land."
#HanifAbdurraqib #Book #Bookclub #Reader #Bookshelf #MusicBooks #bookstodon
Cholesterol & anti tumor T cell immunity:
"We analyze the cholesterol atlas in the tumor microenvironment and find that intratumoral T cells have cholesterol deficiency, while immunosuppressive myeloid cells and tumor cells display cholesterol abundance. Low cholesterol levels inhibit T cell proliferation and cause autophagy-mediated apoptosis, particularly for cytotoxic T cells"
#Immunology #immunotherapy #immunooncology #CancerImmunity
https://www.sciencedirect.com/science/article/abs/pii/S1535610823001423?via%3Dihub
Wolf lamp, could be Roman, but is by @hunchbacksociety
#ceramics #stoneware #handmade #artgallery #ceramic #artmastodon
https://madalenaparreira.com/Hunchbacksociety
If you like the #handmade #ceramics #stoneware from @hunchbacksociety and are in Lisbon today (Saturday) visit 👇
FEIRA DA FRUTEIRA
Curadoria de FELIPA ALMEIDA
26 & 27 Maio
12h - 19h
Campo de Ourique.
If you like the #handmade #ceramics #stoneware from @hunchbacksociety and are in Lisbon today & tomorrow (Friday and Saturday).
FEIRA DA FRUTEIRA
Curadoria de FELIPA ALMEIDA
26 & 27 Maio
Post hoc analysis of data from three phase III trials of atezolizumab in advanced non–small cell lung cancer finds an association between adverse immune reactions and response to treatment.
#cancerresearch #immunotherapy
“She loved to drink, on doctor’s orders of course, and would sit for hours absorbing whiskey-and-soda and Al’s talk. He was wonderful with her; he would start with palmistry, and without her knowing it end with Das Kapital.”
#Books #FoodWriting #Bookshelf #BookClub #Reader #MFKFisher #bookstodon
'We found that the follicular dendritic cell network was smaller in aged mice. Furthermore, the TFH cells that are normally localized within the light zone were instead dispersed throughout the GC in aged mice (Fig. 1), owing to enhanced expression of CXCR4 (a CXCL12 receptor) that directed the TFH cells to the CXCL12-rich dark zone.'
#Immunology #GerminalCenter
Candlestick holder by @hunchbacksociety
#ceramics #stoneware #ceramic #art #handmade #artgallery #artmastodon
FDA approves a fecal microbiota pill for recurrent C. diff infection. My latest #ClinicalPipeline column for Nature Medicine. #Medicine #SciComm #ScienceCommunication #Microbiology https://www.nature.com/articles/d41591-023-00046-2
Joaquim Maria Machado de Assis is one of the greatest novelists ever (though I cant speak to the quality of the translations):
"I had to force myself to finish it. For years, I didn’t pick up another one of his books. When at last I did, I was bewildered by my initial impression. Where first I had been bored, I was now enthralled. Where I had seen salon chitchat, I now saw the musings of genius. I wanted more."
https://www.nytimes.com/2023/05/22/books/review/machado-de-assis-dom-casmurro.html
'So you want to be a writer...'
A good list by Helen Pearson - in Kaaren Janssen & Richard Sever's collection of essays on "Career Options for Biomedical Scientists" (CSH Press).
Amen to #3.
I've worked on all of science, from B cells to T cells.
https://fellowsherpa.com
Joined Nov 2022
