Thiago Carvalho @cyrilpedia@qoto.org
I've worked on all of science, from B cells to T cells.
https://fellowsherpa.com
Joined Nov 2022
Box with rabbit, glazed stoneware, 2023
#thehunchbacksociety #rabitt #ceramics #artmastodon #stoneware #handmadeceramics
Promising but early (phase 2) data on a second generation of anti CD40L monoclonals for #multiplesclerosis
My latest #ClinicalPipeline column for Nature Medicine.
#Immunology #autoimmunedisease #Autoimmunity
“The truth of art keeps science from becoming inhuman, and the truth of science keeps art from becoming ridiculous.”
Raymond Chandler, in The Notebooks of Raymond Chandler.
#books #book #booklover #reading #bookworm #ArtScience #read #bookstodon
Immunological tourism with @mucida & I can confirm that @Plasmacellguy is not an AI generated bot (or a very convincing one).
#immunology
Finding one of @madparreira's aquatints in NY at the home of a prominent collector :)
Stoneware by @hunchbacksociety #Ceramics #Stoneware #Art #artgallery #handmade #artmastodon https://madalenaparreira.com/Hunchbacksociety
Thanks to Delta & 4th of July travel chaos we lived through an extended remix of No Sleep Till Brooklyn (in Logan version). But great to be back.
My latest Clinical Pipeline column for Nature Medicine: second generation anti-CD40L drugs for #MultipleSclerosis. A really cool story of deciphering the biology of adverse effects.
#Immunology #autoimmunedisease #drugdevelopment #monoclonalantibodies
Sorcery!
"Thousands of genes were simultaneously mapped in intact cells & tissues at molecular resolution, revealing the regulatory principles that specify the location and efficiency of protein production for functionally relevant gene programs across different cell types & tissue regions"
'The BRAIN Initiative Cell Census Network (BICCN) is an integrated network of data-generating centers, data archives, and data standards developers, with the goal of systematic multimodal brain cell type profiling and characterization.'
https://journals.plos.org/plosbiology/article?id=10.1371/journal.pbio.3002133
"In this study, we provide a more comprehensive understanding of the relationship among these cellular subsets, uncover a novel homeostatic function in human NK cells, and illuminate how HIV-1 infection disrupts these cellular subsets and their functions"
#HIV #InfectiousDisease #HostPathogen #Immunology #virology
Wang et al @embojournal
A spread from Some Disordered Interior Geometries (1980) © Woodman Family Foundation/DACS, London; MACK
https://www.ft.com/content/12c36952-240f-4898-94bf-e03df83e5883
'In an uncanny anticipation of his subsequent reception history, Johannes Vermeer made one of his first appearances in the printed record in the guise of a phoenix, the mythical bird that regenerates itself from its own ashes.'
https://www.nybooks.com/articles/2023/07/20/life-made-light-johannes-vermeer/
Looks like a Barbeito, #WinesOfMastodon
'But the 25-year bet, at least, has been resolved: No one has found a clear neural correlate of consciousness. Dr. Koch ended the evening by carrying to the stage a wooden box full of wine. He pulled out a 1978 bottle of Madeira and gave it to Dr Chalmers.'
For Throwback Thursday, an episode of the @EMBO Podcast on the clinical use of #phage to treat antibiotic resistant bacterial infection - with a brief stop at the Siege of Leningrad.
Featuring pediatric infectious disease physician Ameneh Khatami, historian Dmitriy Myelnikov, and Jessica Sacher of Phage Directory.
#EMBOPodcast #SciComm #PhageTherapy #Phage #antibioticresistance #sciencepodcast
Oubliette Exhibition at Biblioteca Camoes, Lisbon (Largo do Calhariz, 17). Show runs until the end of June (AKA Tomorrow!).
"The Pignerol Gates. (Rome, circa 1760).
Oubliettes have only one entrance – frequently a trap door on the roof, as was by all contemporary accounts the case of the Pignerol cell. They were constructed so that men could be literally thrown away and forgotten. In Pignerol we know for certain that the gate opened once in 1631 and then again in 1670. The plates you see here were etched in 18th century Rome, by an unknown hand, working from the sketches produced by the guards (the documents were then in the Vatican’s possession, they were transferred to Napoleon by Pius VII and are now in the Archives Nationales)."
Prof. Horst Manfrenjensenden, Ph.D.
Head of Collections, von Willebrand Trust.
#Art #Print #Printmaking #Etching #Handmade #Cartography#ArtGallery #Oubliette #artstagram
@anaanajottajotta @consta_arouca @madparreira@jorgenesbitt
'Zhang et al. provide crucial insights into the mechanisms driving the transition from the onset of autoimmunity to joint destruction in rheumatoid arthritis. The findings emphasize the central role of myeloid monocytes that overexpress both RANK and TLR2, and the sialylation of TLR2 in driving the fusion of monocytes and consequent resorption of bone.'
"The Outer Hebrides Palimpsest. (Edinburgh, Scotland, 1677).
Following the establishment of the Man in the Iron Mask’s identity by use of the correspondence and shopping lists of his jailor, Saint Mars, the Margrave embarked on a reanalysis of one his cartographic collection’s most celebrated collection items, the Outer Hebrides Palimpsest. The connection was tenuous at best: a group of Waldensians fleeing the brutal suppression of the sect in Piedmont arrived at the remote islands at around the time the map was produced. In keeping with our founder’s original mission, the process arrived at no useful conclusions – one unfortunate effect is the damage you see here, the Margrave's effort at redacting the map."
Prof. Horst Manfrenjensenden, Ph.D.
Head of Collections, von Willebrand Trust. Dresden, December 12th, 2022.
#Art #Print #Printmaking #Etching #Handmade #Cartography #ArtGallery #Oubliette
@anaanajottajotta @consta_arouca@madparreira @jorgenesbitt
Oubliette" Exhibition at Biblioteca Camoes, Lisbon (Largo do Calhariz, 17). Show runs until the end of June.
When life gives you lemons, make some of the funniest material ever caught on film.
"Harold (Ramis) embraced the cheapness of SCTV. Eugene (Levy), Catherine (O'Hara) and I were always moaning about how bad the sets looked and how shitty the props were. Harold would just chuckle and go, “That’s part of the charm!”"
I've worked on all of science, from B cells to T cells.
https://fellowsherpa.com
Joined Nov 2022
