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We present #Zebrahub: a timecourse atlas of zebrafish embryonic development, combining #scRNAseq time-course data with #lightsheet live imaging. Explore our seq. and imaging datasets interactively at

biorxiv.org/content/10.1101/20

zebrahub.org
1/n

OLD THREAD REPOST: On #InternationalWomensDay, let's remember Henrietta Lacks.

In October 1951, Henrietta Lacks died from cervical cancer. She is often remembered as the source of the "immortal" HeLa cell line, or as a symbol of grave racial injustice. Who was Henrietta Lacks?

RT @Stephani_Otte
We're hiring! Come join the Chan Zuckerberg Imaging Institute and help build new imaging technologies to reveal the mysteries of our cells within their native context. Join us in this work!
#TeamCZI #hiring #JoinUs #JobSeekers #jobopening chanzuckerberg.com/careers/car

Hopefully the times they are a'changing:

"Such discussions indicate that there exists today both a familiarity with the older custom of senior academics taking credit for others’ work, and a strong distaste for the practice."

blogs.lse.ac.uk/impactofsocial

Worse than useless:

"In the decades since, the military returned to the barracks, but its withdrawal was always conditional. The tenure of Jair Bolsonaro, a former army captain, brought the military back to the heart of government. He might have grudgingly left office, but Brazil’s military — privileged, preponderant and unaccountable — remains a constant threat to the country’s democracy."
cc @mucida
nytimes.com/2023/03/06/opinion

'Altogether, our study identifies an unappreciated site of Yersinia colonization within the murine intestinal mucosa, and reveals an essential function for inflammatory monocytes in maintainance of pyogranuloma architecture during Yp infection.'
fm @BrodskyLab et al

nature.com/articles/s41564-023

"Biotechnology has quietly become America’s newest national security concern. From Congress to the intelligence agencies, Washington’s leaders have concluded that control over biotechnologies will be critical not only to the country’s health, but to national security as well."

ft.com/content/cb9cd845-e9b0-4

The little door behind al this art is my new office in Lapa.
Here's hoping some of the creativity rubs off...

Cancer Immunology Scientist/Sr Scientist - TIL Therapy @RetroBio_

Our leadership team is a group of mission-driven, kind, and thoughtful individuals. We take pride in evolving a work environment that fosters collabor

jobrxiv.org/job/retro-bioscien

#Scie...
jobrxiv.org/job/retro-bioscien

📣 Time to toot some Hippo🦛 & Podocyte🐙 - News:

Nucleoporins and the Hippo signaling effectors YAP/TAZ might balance each other to keep podocytes sound.

Please find the latest preprint from our CRU329 project:

biorxiv.org/content/10.1101/20

A huge THANK YOU to our Hippo team working hard to decipher more details.

#Podocyte #FSGS #Nephrology #HippoSignaling #Nucleoporin #CellBiology #KFO329 #CRU329 #RareDisease #GlomerularDisease

@UniKoeln @CECAD
@nephrology @biorxivpreprint

"We are generating more data in biology than ever. Reanalysis of datasets is increasingly common, and there is a welcome trend toward open data that seeks to remove all barriers (actual and perceived) to data reuse as well as to provide opportunities to assess the reproducibility of analyses."
@richardsever

nature.com/articles/s41592-023

A Seat At The Table For #Science In The UK

Commentary on the launch of the UK Government’s new Department for Science, Innovation and Technology.

forbes.com/sites/drkathmackay/

'To be sure, the flaws in the British pandemic response are well established: Mr. Johnson waited longer than other European countries to impose a lockdown, then kept the restrictions in place for months, prompting fierce internal debate among his ministers. Lack of testing was a huge early problem, most likely worsening the death toll among older people living in nursing homes. There were persistent tensions between scientists advising the government and ministers setting the policies.'

nytimes.com/2023/03/07/world/e

WTF!?

"But this week, Mayor Eric Adams proposed a major reversal: telling shopkeepers not to let in any customers wearing a face covering."

theguardian.com/us-news/2023/m

Loss of #METTL3, and the resulting changes in m6A modifications, leads to enhanced #brain infiltration of monocyte-derived #macrophages in a mouse model of #AlzheimersDisease, promoting Aβ clearance and improving pathology & cognitive decline #PLOSBiology plos.io/3F1ClcQ

'Using two independent real-world datasets from three different countries and an independent validation cohort based on the global, double-blind, placebo-controlled, phase 3 RECOURSE trial, we demonstrate that codon-specific KRAS mutations predict OS benefit for patients treated with the chemotherapeutic agent FTD/TPI in late-stage mCRC.'

nature.com/articles/s41591-023

'Election deniers won races for secretary of state—the post that oversees election administration—in Alabama, Indiana, South Dakota, and Wyoming. They make up most of the Republican freshman class in Congress. Even some of the losers came very close. Lake’s election-denying ticket mate, Abe Hamadeh, lost the Arizona attorney general’s race by 280 votes.'

theatlantic.com/politics/archi

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