#scRNAseq of 18,900 pre-leukemic & leukemic cells reveals transformation of #Hematopoietic #StemCells into full-blown #AcuteMyeloidLeukemia, emphasizing the critical role of #RNAsplicing in the emergence & maintenance of #leukemia #PLOSBiology https://plos.io/3LOnfer
Inside big beef’s climate messaging machine: confuse, defend and downplay https://www.theguardian.com/environment/2023/may/03/beef-industry-public-relations-messaging-machine?CMP=Share_iOSApp_Other
Congratulations to our President, Maria Leptin, on being elected as international member to the US National Academy of Sciences!
Very well-deserved recognition!
🇪🇺 🇺🇸
@theNASciences @MLeptin
#NASmembers
RT @theNASciences: We are thrilled to announce the election of 120 members and 23 international members to the National Academy of Sciences in recognition of their distinguished and continued achievements in original research. http://www.nasonline.org/news-and…
🐦🔗: https://n.respublicae.eu/ERC_Research/status/1653646519898177536
🔥🔥🔥Exciting news! I just published a preprint on the #Ultrastructure of #PrecapillarySphincters and the #NeurovascularUnit. This study is based on the https://www.microns-explorer.org/ dataset by @AllenInstitute. Check 🧵 for more details, including movies of the findings. (1/15)
The Invisible Cities is a book everyone should read.
"No matter how fantastical those places are in Invisible Cities, he reveals that they’re all Venice. They’re all basically Marco Polo riffing about Venice. It’s his childhood home. Calvino touches on the idea of nostalgia, and I think in the ancient Greek sense of nostalgia—in trying to get home, you go off and you have these adventures"
https://lithub.com/darran-anderson-on-the-ever-shifting-magic-of-italo-calvinos-invisible-cities/
"Personalized genome sequencing has revealed millions of genetic differences between individuals, but our understanding of their clinical relevance remains largely incomplete. To systematically decipher the effects of human genetic variants, we obtained whole genome sequencing data for 809 individuals from 233 primate species, and identified 4.3 million common protein-altering variants with orthologs in human."
#Preprint #Genomics #GeneticVariaton
"To capture the complex interplay between the tumor antigenic landscape and anti-tumor immunity in lung cancer, we integrated genomics, transcriptomics, immunopeptidomics, spatial transcriptomics and multiplexed immunofluorescence (mIF) imaging to investigate the antigenic landscape in tumors with variable degrees of immune infiltration"
#Immunology #immunooncology
'Pfizer said it would begin offloading its 32 per cent stake in consumer health business Haleon as it focuses on reducing debt linked to its $43bn acquisition of Seagen and boosting returns to shareholders.'
https://www.ft.com/content/ec441144-52ae-4fa2-8a04-4238db0ee504
'A single dose of the human papillomavirus vaccine is highly effective at preventing infections over three years, most likely lowering rates of cervical cancer and other diseases linked to the virus, according to a new study in Kenya.'
'That sense of phew, though, Bansal said, feels tenuous. The coronavirus’s evolution is not yet predictable; its effects are nowhere near benign. This might be the longest stretch of quasi-normalcy that humanity has had since 2020’s start, but experts can’t yet tell whether we’re at the beginning of post-pandemic stability or in the middle of a temporary reprieve.'
https://www.theatlantic.com/science/archive/2023/05/covid-pandemic-mild-winter-wave-data/673915/
The Oldest Known Globe to Depict the New World Was Engraved on an Ostrich Egg, Maybe by Leonardo da Vinci (1504) https://www.openculture.com/2021/02/the-oldest-known-globe-to-depict-the-new-world-was-engraved-on-an-ostrich-egg.html
Wow. Hindawi is terminating four journals that had been used as dumping grounds for paper mills.
https://retractionwatch.com/2023/05/02/hindawi-shuttering-four-journals-overrun-by-paper-mills/
Impressive work by @deevybee who uncovered this mess in the first place.
Yes, in the olfactory system of #Drosophila, projection neurons respond with the derivative of the olfactory input, albeit somewhat meddled with intensity too (and further confounded by habituation). Useful to navigate odour gradients. See:
"Projection neurons in Drosophila antennal lobes signal the acceleration of odor concentrations" by Kim, Lazar & Slutskiy (2015) https://elifesciences.org/articles/6651
Postdoctoral Fellow in a Klebsiella pneumoniae Lab @DavidAaronRosen
Bioinformaticist, immunologist, or microbiologist? Come join the Rosen Lab studying Klebsiella pneumoniae at Washington University in St. Louis?
#ScienceJ...
https://jobrxiv.org/job/washington-university-school-of-medicine-27778-postdoctoral-fellow-in-a-klebsiella-pneumoniae-lab/?feed_id=44292
Humble beginnings.
(from Robert Kohler's very readable history of drosophila research, Lords of the Fly)
#ScienceCommunication #SciComm #HistoryofScience #Drosophila #books #bookshelf #bookstagram
#Gun #Violence Is Actually Worse in Red States. It’s Not Even Close. Thanks @cyrilpedia !https://www.politico.com/news/magazine/2023/04/23/surprising-geography-of-gun-violence-00092413?ref=thebrowser.com
Postdoctoral Fellow in Leukemia Research @UMassChanMCCB
Come join the cancer researchers at the UMass Chan Medical School as a postdoc.
#ScienceJobs #job
Worcester #UnitedStatesUS #PostdoctoralFellow
https://jobrxiv.org/job/umass-chan-medical-school-mccb-department-27778-postdoctoral-fellow-in-leukemia-research/?feed_id=44286
Etching on copper by @madparreira
#printmaking #art #print #printmaker #etching #handmade #prints #artgallery #artmastodon
https://madalenaparreira.com/Etchings
BREAKING: The pediatrics group suing to ban the abortion drug mifepristone has suffered a major breach. WIRED is reviewing 10K leaked files. The group promotes junk science & anti-trans views and has been labeled a hate group.
https://www.wired.com/story/american-college-pediatricians-google-drive-leak/
I've worked on all of science, from B cells to T cells.
https://fellowsherpa.com