Thiago Carvalho @cyrilpedia@qoto.org

Great animation over at @aeon_co

'Growing up in the 1940s, Ronald Clark had an experience that sounds as if it was plucked from a children’s book – he lived in a New York City public library. And indeed, he believed that living in this ‘temple of knowledge’, where his father worked as a custodian, was a grand privilege, even as it led to feelings of difference among his peers'

https://aeon.co/videos/ronald-grew-up-in-a-new-york-city-library-it-was-as-strange-and-wondrous-as-it-sounds

From a meeting report in #JournalImmunology:

"He (Jonathan Kagan) showed that old mice lose their naive CD8+ T cell repertoire, and the absence of CD8+ T cells in young mice reduces their survival rate. Protective immunity against cancer rises from CD4+ T cells in old mice, whereas CD8+ T cells are responsible for antitumor immunity in young mice."

#Immunotherapy #Immunology #TumorImmunology

https://journals.aai.org/jimmunol/article/209/12/2251/237566/Shedding-Light-on-Immunological-Research-in-Lyon

'Constanze Stelzenmüller, director of the Center on the US and Europe at the Brookings Institution, has said Germany is a case study of a western state that made a “strategic bet” on globalisation and interdependence — and was now suffering the consequences.

“It outsourced its security to the US, its export-led growth to China, and its energy needs to Russia,” she wrote in June. “It is now finding itself excruciatingly vulnerable in an early 21st century characterised by great power competition and an increasing weaponisation of interdependence by allies and adversaries alike.”

https://www.ft.com/content/50a462b3-0e8b-49e1-873c-9505760d4a66

"The current pandemic began in 1961 with the global spread of the El Tor O1 variant. El Tor (or Al-Tur) is a city on the Sinai peninsula where the variant was isolated in 1905; it had once been the site of an Ottoman quarantine station for pilgrims returning from the Hajj. Today, the variant is estimated to infect 1.3 million to 4.0 million people each year, causing 21,000 to 140,000 deaths."

#Cholera #Haiti #NEJM #PublicHealth

https://www.nejm.org/doi/full/10.1056/NEJMp2214763?query=featured_home

'Part of what makes Twitter’s potential collapse uniquely challenging is that the “digital public square” has been built on the servers of a private company, says O’Connor’s colleague Elise Thomas, senior OSINT analyst with the ISD. It’s a problem we’ll have to deal with many times over the coming decades, she says: “This is perhaps the first really big test of that.”

https://www.technologyreview.com/2022/11/11/1063162/twitters-imminent-collapse-could-wipe-out-vast-records-of-recent-human-history/

'A paper published last month in the journal Frontiers in Ecology and Evolution argues that the appetite of the Steller’s sea cow played a major role in shaping coastal ecosystems in northern Pacific waters, particularly the kelp forests that have been devastated in recent years by factors linked to climate change. The paper claims that the sea cow would have made kelp forests more resilient to these changes, and that conservationists may be able to use this knowledge to better protect such ecosystems in the future.'

https://www.nytimes.com/2022/12/05/science/sea-cow-california-kelp.html

"Preprints are a democratising force in science – you have the same opportunity to share your science regardless of whether you're at a small university in a developing country or at a high-profile institute in the USA. Preprints really open up and speed up the dissemination and sharing of research; they are not a one-stop solution to all the problems with science publishing, but are certainly a critical piece."

#Preprint #OpenScience

https://journals.biologists.com/jcs/article/135/22/jcs260793/284135/Cell-scientist-to-watch-Gautam-Dey