Thiago Carvalho @cyrilpedia@qoto.org
I've worked on all of science, from B cells to T cells.
https://fellowsherpa.com
Joined Nov 2022
Thiago Carvalho
boosted
It took us 10 (!) years to get here, but I am thrilled to see the results of this project out
@eLife!
"The therapy, called Hemgenix, gained US approval from the Food and Drug Administration on November 22 to treat patients with severe #hemophilia B. Shortly after its approval, CSL Behring, the pharmaceutical company commercializing the drug, announced its price: $3.5 million for a one-time dose. It’s now the most expensive drug in the world."
https://www.wired.com/story/the-era-of-one-shot-multi-million-dollar-genetic-cures-is-here/
Thiago Carvalho
boosted
Our new Center for Data Science & Environment is hiring! We're looking for 2-3 people in each of the following roles:
- Program Manager
- Data Scientist / Research Software Engineer
- Senior Data Scientist / Research Software Engineer
The center is committed to real-world impact, competitive salaries and supporting careers in this space. Industry applicants welcome. Details in https://dse.berkeley.edu/jobs
Please boost! & reach out with questions! #datascience #jobs #conservation #environment
'Mastodon recently added the ability to edit posts, which has been very advantageous for me, as a typo-prone individual. For Twitter, that feature is still locked behind a subscription. But even before editing was available on Mastodon, there was an option to “Delete and redraft”, which I used frequently to re-post when I had forgotten an image description, or to fix a typo. Mastodon has long provided far more options to control who can see a post and how, which is why I felt more incentive to be creative there than on Twitter.'
https://dantheclamman.blog/2022/12/02/why-i-like-scicomm-on-mastodon/
Thiago Carvalho
boosted
Germany arrested 25 people suspected of planning to overthrow the government, the federal prosecutor said. Many have military training and are suspected of belonging to a domestic terrorist group that believes the country is ruled by a “deep state.” https://nyti.ms/3HfUtSc
Thiago Carvalho
boosted
#OpenAccess journals, please take heed.
New study: "Using a random sample of 300 English language open access journals, we assessed author guidelines to understand image requirements for submissions…We found that most open access journals do not include disability accessibility elements in their guidelines…While over half the journals had required parameters for image submission, none of them required alt text."
https://osf.io/preprints/metaarxiv/zsjqw/
Thiago Carvalho
boosted
We have two open positions #PhD and #PostDoc) in our @fizise team in Karlsruhe. The positions are limited to 2 years with another 2 years extension. For PostDocs, there is the possibility of tenure after 3 years. The 2 positions are in the scope of the #MaterialDigital project focussed on the digitization of #materialsscience including #knowledgegraph #ontologies #knowledgeextraction #nlp #ai #ml
Thiago Carvalho
boosted
Mitochondrial respiration and dynamics of in vivo neural stem cells
In their #OpenAccess Spotlight, Stavroula Petridi, Dnyanesh Dubal, Richa Rikhy and Jelle van den Ameele highlight the key role of mitochondria in neural stem cell transitions.
Thiago Carvalho
boosted
https://podcasts.apple.com/us/podcast/medicine-and-the-machine/id1470296733?i=1000587305078
about randomized controlled trials in medicine and limitations
Thiago Carvalho
boosted
RT @EMBLEvents@twitter.com
📢9 days left to submit your abstract for #EESSymbiosis! @AncestralState@twitter.com @mcsymbiont@twitter.com and @KiersToby@twitter.com have put together a speaker line-up full of experts on all things symbiosis, so don't miss your chance to be a part of the first conference of its kind!
👉🏻 http://s.embl.org/ees23-01
🐦🔗: https://twitter.com/EMBLEvents/status/1599778383910633472
Thiago Carvalho
boosted
Apply before Dec 18 to join the Open Science Retreat on the Kochelsee, April 3-7, 2023!
The LMU Open Science Center will offer travel stipends to applicants who plan to work on creating or fostering an Open Science Initiative at the LMU.
Thirty years ago, in November 1992, Ishida, Honjo and their collaborators reported the discovery of the #PD1 gene in @embojournal
https://www.embopress.org/doi/abs/10.1002/j.1460-2075.1992.tb05481.x
I spoke with Tasuku Honjo, Pierre Golstein (whose team first cloned #CTLA4) & Facundo Batista about the discovery earlier this year.
The initial project had absolutely nothing to do with checkpoints or #immunotherapy
Listen to the full #EMBOPodcast episode at the link below or on pretty much any podcast app
#Immunology #HistoryScience #Cancer #CellDeath
https://www.embo.org/podcasts/from-cell-death-to-cancer-immunotherapy/
Thiago Carvalho
boosted
This is an excellent opportunity! Peter is a sharp mind and is asking extremely cool questions
RT @PRAndersen@twitter.com
📣⌛️One week left to apply for interested PhD candidates https://twitter.com/PRAndersen/status/1593571079313842176
🐦🔗: https://twitter.com/PRAndersen/status/1600431540751638529
Thiago Carvalho
boosted
Massive raids across Germany, arrests of far-right coup plotters including ex-Bundeswehr officers. Qanon influence appears to have played a role in their thinking...
https://www.bbc.co.uk/news/world-europe-63885028
'All that is (at least to me) a rather startling variety of bacteria in such tissues, and I think the authors probably felt so, too. Further work on protein markers of inflammation, immune function, and tumor progression strongly suggested that these bacteria were mostly found in highly immunosuppressed microniche environments. It appears, for example, that T cells are largely excluded from regions with high bacterial colonization.'
- Derek Lowe
#Immunology #CancerImmunity #Microbiology
https://www.science.org/content/blog-post/bacteria-and-cancer-it-s-not-random
Thiago Carvalho
boosted
In Ainu folklore akkorokamui is a red octopus so huge it can swallow ships whole. Its bright red body turns the ocean red and ships know to avoid the sea during this time. This #yokai was both feared and revered as a god.
#DailyFolklore #JapaneseFolklore #japodon #ukiyoe #folklore @folklore
🎨1. Matthew Meyer
2. Utagawa Hiroshige
Thiago Carvalho
boosted
@cyrilpedia Hey Thiago, there are a few. I'm writing one at the moment based on my work at the University of Leeds.
Quick tips:
• Not need to repeat text already in surrounding copy.
• Good to describe why you're using that particular image.
• Good to describe what is in the image. E.G. A white car is in the foreground centre. There are two people to the left middle ground. A wide road winds into the background.
• Alt text is for sight-impaired and movement impaired not just blind people.
Thiago Carvalho
boosted
Here is my #introduction. I'm a scientist working in chemical biology using methyltransferases with synthetic cofactors to transfer click handles, photocages and all kind of stuff to mRNA or DNA.
Thiago Carvalho
boosted
RT @evantthompson
Taking subjectivity seriously: towards a unification of phenomenology, psychiatry, and neuroscience https://www.nature.com/articles/s41380-022-01891-2
Thiago Carvalho
boosted
Open registration begins for the 2023 session of my annual anti-statistics course focusing on causal inference & Bayesian data analsysis & fully coded examples. Lectures will be free online, so no need to register unless you want to join discussions. All details at link: https://github.com/rmcelreath/stat_rethinking_2023/blob/main/README.md
I've worked on all of science, from B cells to T cells.
https://fellowsherpa.com
Joined Nov 2022
