Thiago Carvalho @cyrilpedia@qoto.org
I've worked on all of science, from B cells to T cells.
https://fellowsherpa.com
Joined Nov 2022
Thiago Carvalho
boosted
One step 4x and 12x 3D-ExM: robust super-resolution microscopy in cell biology https://www.biorxiv.org/content/10.1101/2024.08.13.607782v1?med=mas
Thiago Carvalho
boosted
Health Minister Keizo Takemi sat down with the Japan Times to talk about his vision of digitalizing Japan’s health care system, as well as sharing the country’s medical know-how with other Asian nations. https://www.japantimes.co.jp/news/2024/08/14/japan/science-health/health-minister-keizo-takemi-interview-124346/ #japan #sciencehealth #keizotakemi #dementia #aging #pandemic #covid19 #medicine #pharmaceuticals #daiichisankyo #covid19injapan #covid19vaccines
Thiago Carvalho
boosted
💯. Government agencies should be using the Fediverse, rather than a corporation-controlled platform, to disseminate information.
https://mastodon.social/@digiphile/112955002123906994
'Mais de 84% do rendimento dos estudantes (que provém essencialmente da família) é canalizado para despesas relacionadas com o “custo de vida”. A maior fatia é, sem surpresas, para a habitação.'
Thiago Carvalho
boosted
Breaking: fkn stupid antihuman technology does fkn stupid antihuman things more and more convincingly https://arstechnica.com/information-technology/2024/08/new-ai-tool-enables-real-time-face-swapping-on-webcams-raising-fraud-concerns/
'Most relevant for patients, we noted that Vegfa haploinsufficiency in podocytes led to marked endotheliosis, a phenotype of glomerular endothelial cells that is pathognomonic for TMA and the same glomerular injury observed in patients receiving anti-VEGF agents'
Thiago Carvalho
boosted
This is a really good long read on what's going on in Israel, by an Israeli historian and war veteran. He did his PhD on the indoctrination of the army in Nazi Germany, and sees the same things fueling Israel's war crimes in Gaza today. https://www.theguardian.com/world/article/2024/aug/13/israel-gaza-historian-omer-bartov
'The collection of practical guidelines and recommendations described here is primarily intended to facilitate the assessment of cellular senescence markers in living animals (in vivo) and in situ. Finally, this study focuses on cellular senescence research and does not aim to provide information on overcoming the general technological limitations of methodologies, such as autofluorescence for immunohistofluorescence (IHF) or mixed cell populations in tissue homogenates used for RT-qPCR or western blot (WB).'
https://www.sciencedirect.com/science/article/pii/S0092867424006408
Thiago Carvalho
boosted
'It's been believed for some time that being vaccinated against herpes zoster virus confers some resistance to developing dementia later in life. There are a number of lines of evidence, such as this study in Wales that uses the 1933 birth date that was a cutoff for receiving the Zostavax vaccine to show that there really does seem to be a significant effect. And just recently, the same sort of thing has been shown with the newer recombinant vaccine for shingles (Shingrix).'
#Alzheimer
https://www.science.org/content/blog-post/alzheimer-s-and-infectious-disease-story-continues
'None of these software developers has provided information on how effective their algorithm is relative to visual screening by someone with a trained eye for detecting image manipulation. I have written about the need for transparency about the effectiveness of these algorithms, so that users are informed about their capabilities and limitations.'
#ResearchIntegrity
'Evidence from past outbreaks indicates that the viral strain spreading in Central Africa is more lethal than the strain that sparked the 2022 global mpox outbreak, which has since infected more than 95,000 people and killed more than 180.'
'At the same time, the EU’s Digital Services Act (DSA) brought the bloc fresh powers to enforce sweeping rules in areas such as disinformation and advertising, including a penalty that one official who worked on the rules called a “nuclear weapon”: removing access to a social network across the region.'
https://www.ft.com/content/640c68b0-4d3d-4c00-a474-004f58ff98ed
Thiago Carvalho
boosted
So you're thinking about getting #ChatGPT to write something for you...
(Adapted from https://www.linkedin.com/posts/tyulkanov_a-simple-algorithm-to-decide-whether-to-use-activity-7021766139605078016-x8Q9)
Thiago Carvalho
boosted
Single-Molecule Barcoding Technology for Single-Cell Genomics https://www.biorxiv.org/content/10.1101/2024.08.13.607508v1?med=mas
Thiago Carvalho
boosted
Compound screening in primary human airway basal cells identifies Wnt pathway activators as potential pro-regenerative therapies https://www.biorxiv.org/content/10.1101/2024.08.13.606573v1?med=mas
Thiago Carvalho
boosted
Identification of the Polo-like kinase substrate required for homologous synapsis in C. elegans https://www.biorxiv.org/content/10.1101/2024.08.13.607834v1?med=mas
Thiago Carvalho
boosted
Last night was another reminder that when billionaires take control of our most vital platforms for communication, it’s not a win for free speech. It’s a win for oligarchy.
Thiago Carvalho
boosted
Axonal mitochondria regulate gentle touch response through control of axonal actin dynamics https://www.biorxiv.org/content/10.1101/2024.08.13.607780v1?med=mas
Thiago Carvalho
boosted
"Male sex has long been recognized as a potent nonmodifiable risk factor for abdominal aortic aneurysms (AAA). AAA is approximately four to six times more prevalent in men than in women (7), but females experience faster rates of aneurysm growth, and their aneurysms tend to rupture at smaller sizes (...)
In this issue of the JCI, Mu and colleagues present compelling evidence that androgens exacerbate AA by suppressing programmed cell death protein 1 (PD-1) in mice"
#Immunology
Thiago Carvalho
boosted
One of the classic tropes of science fiction is terraforming #Mars: warming up our cold neighbor so it could support human civilization.
The idea might not be so far-fetched.
Injecting tiny particles into Mars’s #atmosphere could warm the #planet by more than 10°C in a matter of months—enough to sustain liquid water.
The scheme would require about 2 million tons of particles per year, they could be manufactured from ingredients found in martian #dust.
https://www.science.org/content/article/terraforming-mars-could-be-easier-scientists-thought
I've worked on all of science, from B cells to T cells.
https://fellowsherpa.com
Joined Nov 2022
