Johannes W. Dietrich @drjwdietrich@qoto.org

Assessing diagnostic tools in #endocrinology with computer simulations https://link.medium.com/qDCugbiYZMb

Einladung zur 2. Endokrinologischen Abendsprechstunde "Up-to-date Schilddrüse 2024" am 25. September 2024.

#Schilddrüse #Nebenschilddrüse #Hypothyreose #Schilddrüsenchirurgie #Syndrom_T #SORSHOT

http://www.endokrinologie.org/resources/flyer-up-to-date-schilddruse-2024.pdf

#Metformin is a useful antidiabetic substance, but also an endocrine disruptor. A recent study shows that it reduces the set point of #thyroid homeostasis, but this effect is mitigated by #vitamin_D deficiency.

https://pubmed.ncbi.nlm.nih.gov/39204438/
https://doi.org/10.3390/pharmaceutics16081093

Which programming language is fit for high-performance computer simulations in biomedical #cybernetics? We found that #Free_Pascal generates faster code than S/R and #Python. Interestingly, Object #Pascal even outperforms #Swift and C++.

https://doi.org/10.14201/adcaij.31762

https://revistas.usal.es/cinco/index.php/2255-2863/article/view/31762

Both sensorimotor and autonomic #neuropathy may be common in #hypothyroidism, despite treatment.

https://link.growkudos.com/1p62a9iults

#Inflammation plays a key role in the pathogenesis of #diabetes mellitus. In our newest paper, we show that treatment of #hidradenitis_suppurativa (#acne_inversa) may cause remission of diabetes. CN: medical images in full text. https://pubmed.ncbi.nlm.nih.gov/39106221/ https://doi.org/10.1111/ddg.15490

#Xylitol consumption may have prothrombotic effects via platelet activation and thereby increase the risk for major adverse cardiovascular events (#MACE). 🧪🩺

https://pubmed.ncbi.nlm.nih.gov/38842092/

Die Grafen von #Neuburg-#Falkenstein waren ein bedeutendes Adelsgeschlecht der #Stauferzeit. Ihr Gebiet reichte von Oberbayern bis Südtirol und Niederösterreich. Ihre Stammburg #Unterfalkenstein wurde bei dem bayerischen #Hochwasser schwer beschädigt. #Klima

https://www.sueddeutsche.de/bayern/unwetter-nach-dem-hochwasser-plan-fuer-sicherung-an-burg-falkenstein-dpa.urn-newsml-dpa-com-20090101-240606-99-299157

Sensorimotor #polyneuropathy may be common in treated autoimmune thyroiditis, but, unlike in other causes of #neuropathy (e. g. #diabetes), it has a unique pattern in quantitative sensory testing (#QST) with low thresholds for mechanical and thermal pain.

https://doi.org/10.1038/s41598-024-63158-w

Should we, therefore, classify #syndrome_T as a psychosomatic disease? This would be premature and probably wrong. We found signs of sensorimotor and autonomic #neuropathy that depend on autoimmunity and #thyroid's secretory capacity (#SPINA_GT).

Our newest paper provides new insights into the conundrum of #syndrome_T / #sorshot. #Anxiety and #depression are significantly more common in autoimmune #thyroiditis compared to healthy controls.

#thyroid #qol

https://doi.org/10.1038/s41598-024-63158-w

Stellenausschreibung für Medizinische Fachangestellte in der Sektion #Diabetologie, #Endokrinologie und #Stoffwechsel am KKB / UK RUB @RUBMedizin.

Wir freuen und auf Ihre Bewerbung!

https://klinikum-bochum.recruiting-portal.com/r/z123d7s3m472p57/Medizinische+Fachangestellte+mwd+Diabetologie+und+Endokrinologie/44791/Bochum

Telefonsprechstunde zu Schilddrüsenerkrankungen

Zum Weltschilddrüsentag am 25. Mai bietet das Schilddrüsenzentrum Bochum eine spezielle Telefonsprechstunde an, die allen Interessierten und Betroffenen offensteht:

Samstag, 25. Mai, von 11:00 bis 14:00 Uhr unter der Rufnummer (0234) 509-6095

Die Deutsche Gesellschaft für #Kybernetik, Informations- und #Systemtheorie hat Peter K. Fleissner und mir den Heinz von Foerster-Preis verliehen.

Ich danke meinen Lehrer:innen und Kooperationspartner:innen, die meine Arbeit im Laufe der letzten 30 Jahre möglich gemacht haben.

Einladung zur Jahrestagung der Deutschen Gesellschaft für #Kybernetik im Rahmen der Jahrestagung der Leibniz-Sozietät in Berlin. Es erfolgt eine parallele Life-Übertragung online:

https://leibnizsozietaet.de/event/27974/

Sadly, John Midgley, a pioneer in #thyroid diagnostics and co-author of multiple papers by our group, passed away. Read Rudolf Hoermann's obituary at The Guardian:

https://www.theguardian.com/society/2024/apr/02/john-midgley-obituary

Our newest paper has been published. Based on machine learning with k-medoids #clustering we identified three different signatures of #thyroid #homeostasis that predict the prognosis of patients with #Takotsubo syndrome.

https://pubmed.ncbi.nlm.nih.gov/38502972/
https://doi.org/10.1016/j.ebiom.2024.105063

Therefore, the non-increased and, in many cases, even reduced beta cell function in metabolic syndrome may not mirror an "either-or" question but be part of continuous evolution. It may be a source of prediabetes and diabetes but also prevent insulinoma.

https://pubmed.ncbi.nlm.nih.gov/38169110/