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The answer to this question may be in glucose toxicity leading to a biphasic response, thereby preventing neoplastic effects of dynamical compensation by mutant takeover.

pubmed.ncbi.nlm.nih.gov/286522

What is the primary event in the pathogenesis of type 2
– dysfunction of pancreatic beta cells or hypersecretion of ? This question is still unsolved and may represent a chicken-and-egg problem.

pubmed.ncbi.nlm.nih.gov/328943

Simulation des Modells des --​es nach Bolie auf einem (THE ANALOG THING)

Simulating Bolie's model of insulin-glucose homeostasis with an analog computer (THE ANALOG THING)

The Apple Macintosh has turned 40. Originally, it was a #Pascal machine, and #ObjectPascal has been developed to evolve its revolutionary operating system.

A novel method for early detection and #endotyping of #Diabetes mellitus relies on software written in #ObjectPascal.

Today, this innovative approach is covered by all major press agencies and news channels all over the globe.

news.rub.de/english/press-rele

#SPINA_Carb has high discriminatory power for the distinction between #diabetes and normal glucose homeostasis. SPINA-GBeta is better than HOMA-Beta, SPINA-GR is better than HOMA-IR and QUICKI, but SPINA-DI is best, being even more powerful than ivGTT. pubmed.ncbi.nlm.nih.gov/381691

Recently, computer simulations with #SimulaBeta played a key role in the development of the fasting-based disposition index SPINA-DI, a substantially improved method to assess the function of the #insulin-#glucose feedback loop and for early diagnosis of #diabetes mellitus. doi.org/10.1111/1753-0407.1352

Early diagnosis of continues to be a challenge. Recently, we developed a disposition index of insulin-glucose from fasting blood samples. The new parameter is not only less expensive but perhaps even better than established measures. doi.org/10.1111/1753-0407.1352

Total step-up #deiodinase activity (#SPINA_GD) is upregulated in metabolic syndrome, as demonstrated by a strong correlation to the triglyceride-glucose index. pubmed.ncbi.nlm.nih.gov/379462 doi.org/10.1186/s40001-023-015

's secretory () is higher in borderline personality disorder () compared to controls. Is this a result of dynamical compensation or from sympathetic innervation of the thyroid gland? doi.org/10.3390/jcm12216702

hormones profoundly affect the heart. This also applies to chronic stress and type 2 allostatic load, where they relay signals from the brain to the heart. Our newest study observed an elevated thyroid output in borderline personality disorder. doi.org/10.3390/jcm12216702

2. Tag der : Vielfältiges Programm am Patiententag u. a. mit Dorothee Linnenbrink (aidhere) zu , den DiaEngeln und Antonia Vering aus unserem Team.

endokrinologie.org/tdt_2.html

2. Tag der Diabetestechnologie
20. und 21. Oktober 2023, St. Josef-Hospital Bochum

Zertifiziert mit 4 CME-Punkten (Ärztekammer Westfalen-Lippe @aekwl_kom) bzw. 7 Punkten (VDBD)

endokrinologie.org/tdt_2.html

Zum 2. Tag der lädt das Katholische Klinikum am Freitag und Samstag ins Hörsaalzentrum des St. Josef-Hospital ein. Eine Anmeldung nicht erforderlich. endokrinologie.org/tdt_2.html

1. Endokrinologische Abendsprechstunde im Hörsaalzentrum des St. Josef-Hospitals „Up-to-date 2023". Die Veranstaltung richtet sich an Patienten, Hausärzte, Angehörige und Interessierte. Eine Anmeldung ist nicht erforderlich. klinikum-bochum.de/medien/term

Einladung: Zweiter Tag der .
20. und 21.10.2023, Universitätsklinik St. Josef Hospital

Informationsveranstaltung für Betroffene und Interessierte
Medizinisch-wissenschaftliches Programm
Industrieausstellung

sci.events/e_159/tdt2/

Does impaired transport of hormones into the central nervous system contribute to / ? A recent study observed CSF/serum FT4 ratio to be associated with in treated . doi.org/10.1111/jne.13272

Is reduced quality of life in a psychological issue? A poster presented at suggests this. It is, however, impossible to prove causality in a case-control study. We need prospective studies to understand / . doi.org/10.1530/endoabs.90.P27

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