Sneaking in one more publication before the holidays! 🎅🏽🎄
With postdoc Dr. Sateesh Dubbu and Dr. Jampani Santhi, we elaborate on the uses of carbohydrate-based dienes as privileged scaffolds for the synthesis of pharmaceutically-interesting molecules
https://onlinelibrary.wiley.com/doi/abs/10.1002/hlca.202200135
If anyone is interested in #GiantViruses, large #Phages, or the ecological and evolutionary complexity of #viruses in general, you may wish to check out a review I wrote with @giant_virus
https://www.mdpi.com/2218-273X/12/8/1061
This was a lot of fun to write! And part of a special issue commemorating Ivanovsky's discovery!
#introduction #chemiverse #chemtoots
Nice to have made the move over. I’m a pharmaceutical analytical chemist with a background in org/medchem. I run a team that focuses on novel DS control strategy development across all clinical phases.
I love reading about the wonderful new developments in science, pharma comings-and-goings, and (per my Canadian heritage) hockey. The old chemistry community we had on the bird site was fantastic, and looking forward to trying to rebuild that here.
I am part of the great #twittermigration and joined about a month ago. 🤗 Been getting my head around tooting and boosting. So here is my intro (folllowed #fedtips). I like to talk about #science #chemistry #leadership and #diversity. I am an advocate for #womeninstem. I am not based in Scotland but it is close to my heart as somewhere I lived for some years. Plus I live nearby! #Cumbria. I am hoping more of my bird community will move across. So any tips on how to help them welcomed. Thanks!
RT @DrNenehS
Calling all early career #African researchers to submit proposals for the GSK Africa Open Lab on #InfectiousDiseases.
Each award is up to £75,000 plus mentoring, scientific and technical support
Applications close 17 Feb 2023.
More info: 👉🏾 https://www.gsk.com/en-gb/responsibility/africa-open-lab/#how-to-apply
#BeatNTDs
A front page article on the Washington Post telling people how to get started with Mastodon?
That’s a big deal.
https://www.washingtonpost.com/technology/2022/12/17/how-to-join-mastodon/
The Melting Arctic Is Releasing Ancient Germs – How Worried Should We Be?
The youngest #virus to be revived was a sprightly 27000 years old. And the oldest (a #Pandoravirus) was around 48500 years old. This is the oldest virus ever to have been revived.
As the world continues to warm, the thawing #permafrost is releasing organic matter including #bacteria and #viruses – some that can still reproduce.
Olfactory Viral Inflammation Associated With Accelerated Onset of Alzheimer’s Disease
Alzheimer’s disease onset may be accelerated by viruses that inflame and disrupt signals from the olfactory system to the hippocampus, a new study reports.
#Neuroscience #Neurology #NeurologicalDiseases #NeurodegenerativeDiseases #Alzheimer #Dementia #Neurovirology #Viruses #Brain #OlfactorySystem #Hippocampus #Neuroinflammaton #Inflammation
https://neurosciencenews.com/olfactory-inflammation-alzheimers-22077/
NPP-669 is a promising #Cidofovir #prodrug acting as #broad #spectrum #antiviral agent (#BSAA) against multiple DNA #viruses.
An excellent example on how #chemistry / #medicinalchemistry play a key role in the improvement of #drug #bioavalilability and clinical efficacy of #drug candidates.
https://pubs.acs.org/doi/full/10.1021/acs.molpharmaceut.2c00668#
#introduction: I am an Independent Fellow at #UniversityofNottingham running a research group focussed on using #bioinformatics, #microbiology, and #evolution to understand microbe-#microbe interactions in the human #microbiome (primarily in #cysticfibrosis).
What happens when you get more than one respiratory virus? My lab Yale studies this, and there are many open questions. This article discusses current research including the surprising phenomenon of interference among unrelated viruses. #COVID #flu #infectiousdisease https://www.the-scientist.com/news-opinion/what-happens-when-you-catch-more-than-one-virus-70817
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RT @HartungIngo@twitter.com
The #SRPK family of kinases is implicated in the regulation of alternative splicing & cancer. @TimoHeinrich71@twitter.com @merckgroup@twitter.com & @thesgcfrankfurt@twitter.com now report the pan-SRPK probe MSC-1186 which exploits unique hinge region features @ACSBioMed@twitter.com https://pubs.acs.org/doi/10.1021/acs.jmedchem.2c01705?fig=abs1&ref=pdf #OpenScience
🐦🔗: https://twitter.com/HartungIngo/status/1603683953558396928
Check out oir findings on how strong responses to #CMV correlate with IL-17 responses to #SARS-CoV-2 - a correlation maybe worth investigating and thinking about it #co-infections. https://link.springer.com/article/10.1007/s00430-022-00758-1
Just joined Mastodon & hello everyone! My lab works on #ChemicalBiology and #DrugDiscovery. I mainly tweet about science, education, academic life in general. I’m still active on Twitter @Billy_WL_NG.
Feel free to reach out for collaborations😉 website: https://ngwailung.com
🔴 The 3rd edition of the #COLOTAN #symposium will be held in #Parma 🇮🇹 on the 27th of January, 2023, entitled “#Gut #disorders and possible impact on #colonic #drug #targeting: An excursus on the most common #gastrointestinal disorders and on their potential effects on drug disposition.” #IBD
#Registration is #free but mandatory!
Would you like to contribute with a #poster? Please send your #abstract (max 1 page) to rabab.nasser(at)kuleuven.be
I'm a freelance #illustrator - I love all things #microbes and #cartoons - find me here and...
My website for my portfolio: https://lizawolfson.co.uk
Insta for #WIP and studio life of #freelance #ScienceIllustration: https://www.instagram.com/eliza_coli/
Ko-fi for #microbiology #sciart and #comics content: https://ko-fi.com/intothemicroverse
I'm on discord as @eliza_coli too, so don't be a stranger!
Hi everyone! I'm @basktastic on Twitter but am trying out my real name here. My #chembio #cellbio #lipidtime lab at Cornell develops tools for imaging and editing the lipidome, drawing on #bioorthogonal chemistry, #clickchemistry, #chemoproteomics, #optogenetics, #directedevolution, and more. https://baskin.wicmb.cornell.edu
Professor of Medicinal Chemistry at the University of Parma (Italy).
Developing novel drug candidates for Chronic and Infective Diseases.
Interests:
#MedChem #MedicinalChemistry #DrugDiscovery #Chemistry #MultiTarget #Antiviral #Antibacterial #Anticancer #IBD #CVD #Alzheimer #CysticFibrosis #Medicine #Pharmacology #Biotech #ccr6 #pcsk9 #bsaa