NPP-669 is a promising #Cidofovir #prodrug acting as #broad #spectrum #antiviral agent (#BSAA) against multiple DNA #viruses.
An excellent example on how #chemistry / #medicinalchemistry play a key role in the improvement of #drug #bioavalilability and clinical efficacy of #drug candidates.
https://pubs.acs.org/doi/full/10.1021/acs.molpharmaceut.2c00668#
-Time for a short #Introduction-
I am a group leader in #MedicinalChemistry at the University of Parma. My lab combines #chemical & #computational techniques to develop novel pharmacological tools to study different Chronic Diseases (#CysticFibrosis, #IBD, #Hypercholesterolemia, #Alzheimer, #Cancer) and Infective Agents (#SARSCoV2, #Enterovirus, #Flavivirus, #Monkeypox, #HIV).
We are particularly interested in the development of #MultiTarget inhibitors and open to new #collaborations in #DrugDiscovery.
#Tooting (sooner or later) about the #chemistry and #science
Professor of Medicinal Chemistry at the University of Parma (Italy).
Developing novel drug candidates for Chronic and Infective Diseases.
Interests:
#MedChem #MedicinalChemistry #DrugDiscovery #Chemistry #MultiTarget #Antiviral #Antibacterial #Anticancer #IBD #CVD #Alzheimer #CysticFibrosis #Medicine #Pharmacology #Biotech #ccr6 #pcsk9 #bsaa