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Our latest: Deep dynamical modelling of developmental trajectories with temporal transcriptomics

- Optimised metabolic labelling for time resolved scRNAseq
- Deep learning (VAE) for RNA velocity
- Predicting expression dynamics with a neural SDE system

biorxiv.org/content/10.1101/20

204 Mastodon posts with the #PositConf2024 hashtag so far in my app! Search through them all here, on a Web page that includes NONE of today's advice on how to make Quarto docs or apps look nice 😅
apps.machlis.com/shiny/positco

Drawing: Possible causes of your problems. I've been appalled at the scenes we've witnessed over the last few days. It's utterly unacceptable that people should have to live in fear because of the colour of their skin.
[Polite comments only, please.]

I wrote a thing about switching from Windows to Linux for music production. Not a step-by-step guide, but a bunch of (hopefully) helpful info and links for those who might be considering the switch. Will probably also be useful for those new to the whole computer music thing who are interested in Linux as a starting point.

#LinuxAudio #MusicProduction

fstateaudio.com/?page_id=1763

As a Blind person i never thought i would be on social media savoring photos. But the communal Mastodon alt text game is so strong that sweet, poetic or silly descriptions abound on my timeline. Thanks to legions of people who take time to write a meaningful description of the ephemera they post, i learn so much about insects, plants, buildings, memes — all dispatches from a dimension of the world that i otherwise wouldn't experience. If you're wondering whether anybody reads these things: YES.

theguardian.com/technology/art

"Arbaugh initially faced issues after his surgery when the tiny wires of his implant retracted, resulting in a sharp reduction in the electrodes that could measure brain signals. Reuters has reported *Neuralink was aware of this issue from its animal trials*. [...] Musk also said he has spoken with Donald Trump, who he has endorsed in the US presidential race, about forming a commission aimed at improving “government efficiency” through *reduced business regulation*, and would be willing to participate. Musk said that in his view US regulations hamper innovation."

Of course, ethical and safety considerations as usual are not in Elon Musk's book; nor is openness.
Brain computer interfaces are the last area where you want reduced regulation...

Did you forget to write some slides? do you want something quick and easy? try using my new quarto revealjs plugin: loud

All text on slides are automatically centered and zoomed in to fill the screen

github.com/EmilHvitfeldt/quart

"Our framework suggests that after accounting for heterogeneity, the probability that the tested hypothesis is true for the average population, design, and analysis path can be much lower than implied by nominal error rates of statistically significant individual studies." #MetaSci #Methodology 🧪

Heterogeneity in effect size e...

How do you folks deal with random invitations to for you never heard of?

I usually just delete the email and not engage as usually these are random topics I have zero expertise in... today, however, I received a paper about something (kind of) related to some work I've done in the past. Reading the abstract I can already see very major issues with it so... should I put time and effort to prevent obviously bad work to be published? Or is this a battle not worth fighting?

Interesting article on "reusable" products

"An entire generation has been socialized to participate in environmentalism by way of consumerism"

theguardian.com/environment/ar

New Python Shiny app for my image analysis course deployed!

This will accompany the lecture on edge detection methods.

apps.nicolaromano.net/EdgeDete

Source code is here, feel free to reuse!

github.com/nicolaromano/BIA4/t

@LianaBrooks excellent points! May I add:

Privilege comes in many shapes and sizes, it’s not all-or-nothing, so you can have various types of privilege without having every possible advantage in life. You can have struggles & suffer injustice and still have privilege in some form. You can have privilege in one area and lack of privilege in another.

"Freshening up" the material for my course restarting in September.

A lot of my students will be essentially novices... so here is some short Python starting/refresher material! Everything's CC-BY-4.0 so feel free to reuse!

github.com/nicolaromano/BIA4/t

‪Looking for literature for review paper:
Is there quantitative data that beauty/aesthetics in charts help user engagement/effectiveness/memory?

#Datavisualization #DataViz #ComputerScience

Everybody's Free (To Write Websites)

Enbies and gentlefolk of the class of '24:

Write websites. If I could offer you only one tip for the future, coding would be it. The long term benefits of coding websites remains unproved by scientists, however the rest of my advice has a basis in the joy of the indie web community's experiences. I will dispense this advice now:

I can't believe that in 2024 we still have to explain so bluntly that "Academic journals are a lucrative scam". Yet here we are ...
Kudos to the Editorial Board of Philosophy & Public Affairs for resigning en masse and thank you to Arash Abizadeh for explaining why and what's next in the Guardian:
theguardian.com/commentisfree/

"'With the R515 driver, #NVIDIA released a set of #Linux GPU #kernel modules in May 2022 as open source with dual GPL and MIT licensing. […]

Two years on, we’ve achieved equivalent or better application performance with our open-source GPU kernel modules […]

We’re now at a point where transitioning fully to the open-source GPU kernel modules is the right move, and we’re making that change in the upcoming R560 driver release. […]'"

developer.nvidia.com/blog/nvid

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