Julien Delpierre @JulienDelpierre@qoto.org

Hi! I am an Associate Professor and the head of the Laboratory of Cardiovascular Cell Biology at Vanderbilt School of Medicine (AKA The Burnette Lab). I also design clothing (mostly activewear) featuring photographs of cells taken through a microscope (Mag2Art.com).

Hello #ScienceMastodon ! I just made the Twitodon transition so a bit of #introduction: I'm a PhD Student interested in #DevelopmentalBiology, #Embryology and sometimes #StemCells and #Transcription. Looking forward to less promoted posts and more #AcademicToots.

Don't forget that Janelia's Computation & Theory area is looking for both [Senior] Group Leader candidates (https://www.janelia.org/our-research/our-labs/group-leaders) and Theory Fellows (https://www.janelia.org/our-research/overview/theory-fellows)! Are you working on interesting computational and theoretical approaches to address fundamental biological questions? Talk to us!

Rab8-, Rab11-, and Rab35-dependent mechanisms coordinating lumen and cilia formation during Left-Right Organizer development. https://www.biorxiv.org/content/10.1101/2022.10.31.514532v1 #Morpholino

I thought I would share this image, which I took a while ago, but that I really like! This is a #pituitary gland where cells expressing a protein called proopiomelanocortin (POMC for short) have been coloured in green. You can see two groups of cells; a very packed band in the middle and some sparse cells on the sides. The first are called melanotrophs, and they are important in determining skin and fur colour. The sparse cells on the sides are called corticotrophs (and that's what I am studying at the moment!) and they are important for the response to #stress . They secrete an #hormone called ACTH which stimulates the production of the stress hormone cortisol from the adrenal gland. At the moment we are trying to understand what happens to this cells after the body is exposed to stress for a prolonged amount of time. #scicomm #biology #science #physiology #microscopy

📢 📢 Exciting chance to come join us on a #rotation-based, 4 year, international #PhDStudentship- include our #TubulinCode project! Closing date: 9th January 2023. #imaging #cytoskeleton #cilia #ciliopathies #GenomeSurgery #RareDisease Message me, if you want to hear more! 📢 📢

More info: https://www.ed.ac.uk/mrc-human-genetics-unit/graduate-research-and-training/four-yr-international-prog-human-genetics-genomic

We know that #centrosomes are not required for mitotic division, so what are they good for?

New preprint from the lab shows that having two duplicated centrosomes at the beginning of #mitosis facilitates rapid bipolar spindle formation. In the absence of centrosomes there is a checkpoint-mediated delay that is required to give enough time to sort things out and assemble the spindle.

#CellBiology
https://www.biorxiv.org/content/10.1101/2022.11.08.515699v1.full.pdf

Moving toward a better #resolution: our structured illumination microscope (SIM) allows to get 2 times better detail than classical widefield or #confocal #microscopy. Here's a #cellfie of a monkey cell labeled for the endoplasmic reticulum (yellow), clathrin (blue) and #actin (gray) 🔬

For a few months now I've considered doing a series of posts on women in #RNA #research (mostly PIs, maybe some #postdocs). My idea is to take the latest paper of their group and present it while highlighting previous key work. I already have a list of ~50 researchers (biased for those I know) - enough for a year of a weekly series.
Originally, I thought of doing it on the birdsite, but I just couldn't find time for it.
Moving here might be the kick I need to begin - hopefully this weekend.

As a #colourblind person, I appreciate people checking their figures in greyscale. But it's a lot of work to always convert your figures into greyscale, right? A lesson from digital artists: you don't have to!

There are easier ways for all operating systems! (see replies)

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Checking your figures in greyscale may not resolve all visual impairment issues, but it really helps! Plus, it allows YOU to appreciate *contrast*. Use contrast to your advantage!

Protip for Tweetdeck lovers new to Mastodon: click "Preferences" and select "Enable advanced web interface".

You'll love the result. You can add columns for hashtags, lists, etc.

I'm a professional dog sitter doing a postdog at Stanford co-advised by two Samoyeds 😅 I do single-molecule force spectroscopy as a side hustle! I’m enthusiastic about proteins especially kinases in AFM, magnetic tweezer and optical tweezer assays! Follow me for #biophysics #singlemolecule #mechanobio content 🤗

#introduction #introdogtion

Did you know that you can copy-paste images into the text field, and they get added to your toot as if you had appended them? Very handy to avoid creating intermediate files, by right-click on a PDF, copy image, and paste here; or right-click on an image on a website, and paste here.

Did you know that you can follow hashtags? A convenient way to follow entire domains of knowledge without having to find its members first.

Did you know that the website works perfectly from a mobile web browser? No need for an app; the latter are often better looking, but lack some of the functionality.

Did you know that starring a toot doesn't promote it? It's only like an "I see you" and a bookmark of sorts. (The is also a bookmark button, which is just that, without telling the sender.) If you want to promote a message, boost it.

#mastodon #feditips

@minimammoth @academicchatter I think it's very unfortunate when I see academics publishing great stuff under the more restrictive licenses like the ones that contain -NC or -ND

Do they realise that putting those restrictions on their work means that the figure images cannot be re-used in Wikipedia? This is particularly bad for papers describing new species - wikipedia needs photos of those species!!
https://commons.wikimedia.org/wiki/Commons:Licensing

Have just realised that #academics can use @ORCID_Org to
#verify themselves.

Just include your full mastodon link (like this: https://mas.to/@marekmcgann) in the "Websites and Social Links" section in ORCID, then include link to your ORCID record in your Mastodon profile.

Hurray for distributed digital identities!

Mastodon: an introduction for beginners and for scientists

Via ⁦@giorgiogilestro⁩ https://giorgio.gilest.ro/2022/11/05/mastodon-an-introduction-for-beginners-and-for-scientists/

Word of the day:

"Kleptoplasty, the process by which a host organism sequesters and retains algal chloroplasts, is relatively common in protists"
#chloroplast

https://journals.plos.org/plosbiology/article?id=10.1371/journal.pbio.3001857

Come be our colleague! Six open positions in the Department of Life Sciences at Imperial College London. Cell and Dev Biol, Infection and Immunity, Molecular Mechanisms of Disease, Plant Sciences, Biotech and Bioengineering, Chair in Microbiology. Great department, great students, great colleagues.
https://t.co/TmLndtliLD
https://t.co/nEjKYn7c4E
https://t.co/JKghC2VScD
https://t.co/IWexgIf6t3
https://t.co/lfP4dCwhih
https://www.imperial.ac.uk/jobs/description/NAT01313/chair-microbiology/
#academicjobs

I am looking for two PhD students. Two very diverse PhDs, but both in the same project on inflammatory bowel disease.

The first will focus on real-world data, artificial intelligence and FAIR data infrastructure --> https://www.academictransfer.com/en/319737/phd-in-data-science-focusing-on-federated-learning-applied-to-healthcare-at-the-clinical-data-science-group/

The second will focus on both qualitative and quantitative research on clinical implementation of AI, clinical decision support or decision aids --> https://www.academictransfer.com/en/319734/phd-candidate-on-real-world-data-focusing-on-the-bridge-between-technology-and-medicine/

#AI #IBD #healthcare #FAIR #artificialintelligence #vacancy #PhD