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Is it worth reading today? I am curious as to whether her ideas were selectively employed by the right and might actually be more complex, just as how has been massively misunderstood and misused. Love to hear any thoughts on this before I search for one of her books

'Here, we used genetically diverse C. elegans strains to perform dose-response analyses across 26 anthelmintic drugs that represent the three major anthelmintic drug classes (benzimidazoles, macrocyclic lactones, and nicotinic acetylcholine receptor agonists) in addition to seven other anthelmintic classes.'

biorxiv.org/content/10.1101/20

Nothing in biology makes sense except in the light of RNA sequencing, but what if you can't analyze the data? We (mostly Guy) created a software to make your life easy! Read our NEW preprint & REBLOG. Please try it (follow the detailed tutorial) and give us feedback! 🤟🙏

"RNAlysis: analyze your RNA sequencing data without writing a single line of code"
biorxiv.org/content/10.1101/20

Here's Guy's thread with all the details:

twitter.com/GuyTeichman/status

@mikemaddenwx Stop recording GDP and quarterly growth at all in the developed world.

This is undoubtedly exciting new tech but there is no easy "technological fix" for the . I think that we have to realise that developed countries need to scale back our consumption drastically, even if that means less growth and reduced standard of living (hopefully only for the richer members of society).

Karen Mardahl  
Intriguing news from George Monbiot in the Guardian on precision fermentation, which I had never heard of before. https://www.theguardian.com/comme...

On the basis of the theory that the worse something tastes the better it is for your health, those ginger shot things they are handing out manically in over the last few days must be some kind of miracle cure for all ailments.

@santolini comment ces chiffres ont été calculés? Pourquoi est la france la plus haute? [pardon pour mon francais mauvais]

Research on toxoplasma in wolf populations: "The effect of TOXO[toxoplasma positive test] was positive ...With an odds ratio of 46.06 (exp[3.83]), the odds that a seropositive wolf becomes a pack leader is more than 46 times higher than a seronegative wolf becoming a pack leader."

Extraordinary result. I think one would need to do an experimental infection to be sure that this is not due to some complex confounder. But super-interesting idea.
Paper here:

nature.com/articles/s42003-022

Tooted a while back about Vertigo. Now reading his second, The Rings of Saturn. Suddenly I get what he is about. An astonishing work using a long walk around the Suffolk coast as a springboard for wide-ranging discussions on history, literature and the environment. In that regard it is also prescient, lamenting on the and how it was affecting the Suffolk countryside even when the book was written in the early 90s. Strongly recommended.

Shortlisted for "word of the year 2022" in UK is apparently "goblin mode". I misread it initially as globin mode which would have been much more exciting.

Eugenics- a cautionary tale of how science can be misused- and in some ways is still influencing thought today. Gripping and urgent account from Adam Rutherford on this BBC radio4 program:
bbc.co.uk/sounds/play/m001fd36

Looks like citizens in the developed world will have to do more than their governments if is to be kept to 1.5C. I think it's possible- but it's going to be very difficult.

in . New paper from Hanne De Kort and others. Increased heterozygosity in lyrata is found near to TEs, and is hypothesised to play an important role in maintaining diversity despite inbreeding. Curiously the SNPs downstream of transposon start sites are enriched in genes with roles in stress resistance but not upstream. Interesting idea that this represents a selective advantage to maintaining TEs but, as authors acknowledge, might not be a direct relationship (i.e. TE spreading may result in increased mutation rate, which selection could then act on, even if TEs themselves are neutral or deleterious). Interesting to see if this is found in other species.
Link:

nature.com/articles/s41467-022

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