Thiago Carvalho @cyrilpedia@qoto.org

For #throwbackthursday, a blog post from 2013 by Washington University's Joan Strassmann, on the IGC PhD course she participated in as guest faculty back when I was running the PhD program.

https://sociobiology.wordpress.com/2013/05/05/journal-club-extended-to-research-planning-for-students-at-the-gulbenkian-in-portugal/

Oded Rechavi: “There are a few open questions that are very big, like can epigenetic inheritance, which is typically transient, affect the process of evolution.”

#SciComm #EMBOPodcast #Epigenetics #SciencePodcast #ThrowbackThursday

https://www.embo.org/podcasts/physiologically-irreverent/

As talk about developments in #AI explodes, who do we trust more, humans or computers?

🎧 Listen to the #eLifePodcast where Marco Wittman explains research on how we take on information: https://elifesciences.org/podcast/episode86?utm_source=mastodon&utm_medium=social&utm_campaign=organic

Lilly walks away from Nektar's PEG conjugate of rhIL-2, rezpeg - aka rezpegaldesleukin, aka NKTR-358 - after disappointing phase II results in lupus.

#Immunology #immunotherapy #RegulatoryTCell #Lupus #Treg #drugdevelopment

https://www.fiercebiotech.com/biotech/after-gathering-enough-nektar-lilly-hands-backs-rights-immunology-med-post-lupus-fail

"The rabbits’ “interracial” union had inflamed Montgomery's chapter of the White Citizens’ Council, whose members argued that the book amounted to grooming by literary means, conditioning preschoolers to cross the color line. Essentially a white-supremacist chamber of commerce, with a fast-growing network across the South in the wake of the U.S. Supreme Court’s Brown v. Board of Education desegregation decision in 1954, the council used its dollars and clout to stoke economic intimidation and violence against the burgeoning civil rights movement. These segregationists were ideological ancestors of today’s book challengers, such as those in a Florida school district that recently banned “And Tango Makes Three,” about two male chinstrap penguins who create a family. Across time, those who ban books have shared a deep aversion to anything that promotes changing definitions of marriage and family."

https://www.nytimes.com/2023/04/26/books/review/garth-williams-the-rabbits-wedding-banned-books.html

'Para o vice-presidente do PSD, estamos perante um problema de falta de juizinho e de bom senso dos dirigentes do Chega, e isto, já se sabe, são coisas da vida que não vale a pena dramatizar.'

https://www.publico.pt/2023/04/28/opiniao/opiniao/nao-sao-nada-racistas-sao-marotos-2047695

Research Technician I - Yeh Lab

https://jobrxiv.org/job/cold-spring-harbor-laboratory-27778-research-technician-i-yeh-lab/?feed_id=43830

#ScienceJobs #job
Cold Spring Harbor #UnitedStatesUS #ResearchTechnician
https://jobrxiv.org/job/cold-spring-harbor-laboratory-27778-research-technician-i-yeh-lab/?feed_id=43830

🧐 #MeetTheSpeaker!

🔬 How can single molecule sequencing technologies change research on the human genome? Listen to Davide Bolognini, Senior Bioinformatician in our Genomics Research Centre.

“International collaborations, of course, are an essential part for developing new methods”

#lifesciences #humantechnopole #genomics #singlemolecule #sequencing #humangenome #science #sciencemastodon

https://youtu.be/Ka85RhFkPOU

On authorship and gender equity | Science https://www.science.org/doi/10.1126/science.adh2719
Totally unsurprising findings that women are worse off then men

Postdoctoral Fellow

Postdoctoral position in Cancer Cell Biology

https://jobrxiv.org/job/university-of-california-san-francisco-27778-postdoctoral-fellow-2/?feed_id=43824

#ScienceJobs #job
San Francisco #UnitedStatesUS #PostdoctoralFellow
https://jobrxiv.org/job/university-of-california-san-francisco-27778-postdoctoral-fellow-2/?feed_id=43824

"However, T cell responses to dietary antigen have primarily been characterized using monoclonal T cell receptor (TCR) transgenic systems which do not represent a physiological immune response. Polyclonal CD4+ T cell responses to food, including TCR-specific selection and functional differentiation, remain largely uncharacterized and are critical for understanding mechanisms of tolerance and allergy."
Lockhart, @mucida et al

#Preprint #Immunology #OralTolerance #MucosalImmunology

https://www.biorxiv.org/content/10.1101/2023.04.11.536475v1

"Yet officials with the National Academies have kept quiet about one thing: their decision to accept roughly $19 million in donations from members of the Sackler family, the owners of Purdue Pharma, the maker of the drug OxyContin that is notorious for fueling the opioid epidemic."
cc @mucida

https://www.nytimes.com/2023/04/23/health/sacklers-opioids-national-academies-science.html

'In this study, we report that high CDK6 expression positively correlates with immunotherapy resistance in 6 of 7 single-agent immunotherapy clinical studies for melanoma patients. CDK6 depletion, but not that of CDK4, cyclin D1, or D2, in cells of the TME inhibits tumor growth.'
#immunotherapy #immunology

https://www.cell.com/cell-reports/fulltext/S2211-1247(23)00325-X

@neuroecology

Looking for #neuroscience? Or #Celegans? or #Drosophila? Or #connectomics? Or #brains, #entomology, #academia, #nativebees? Different place, different approaches – tags here are useful and can be followed.

For accounts, @PhiloNeuroSci selects and comments on neuroscience papers; @eLife and @PLOSBiology publish their papers and digests.

@NicoleCRust challenges us all often; @matrig and @kristinmbranson publish at the intersection of neuroscience and computer science; John @tuthill, @BorisBarbour, Jason Shepherd @jasonsynaptic , @mtarr @gepasi, @cian, @schoppik, @MatteoCarandini, Dan Goodman @neuralreckoning, Bryan @BWJones, @achterbrain, @CoriBargmann and many others publish on neuroscience among other topics.

On open access and #ScientificPublishing there's Stephen Eglen @sje, Stephen Royle @clathrin

I am living many out ... the list is long. One way to find them is via tags like #neuroscience.

Big accounts like Doctorow @pluralistic, @Carl_Zimmer, @jwz, and @timkmak are here too. There are many more.

There are useful bots like, for me, @flypapers – I wish I could filter for neuro-only papers, but the volume isn't high. Then there're neuroscience-specific servers like synapse.cafe and neuromatch.social – their local timelines may reveal further accounts you may like.

Postdoctoral Scientist - Cell Cycle/Cell Metabolism

Post-Doctoral Researcher Fellow or Research Associate positions are available in the Center for Childhood Cancer and Blood Diseases.

https://jobrxiv.org/job/nationwide-childrens-hospital-27778-postdoctoral-scientist-cell-cycle-cell-metabolism/?feed_id=43788

#ScienceJobs #job
Columbus #UnitedS...
https://jobrxiv.org/job/nationwide-childrens-hospital-27778-postdoctoral-scientist-cell-cycle-cell-metabolism/?feed_id=43788