Johannes W. Dietrich @drjwdietrich@qoto.org
- Sektion DES / Klinik
- http://www.endokrinologie.org
apl. Prof. Dr. med. Johannes Dietrich, endocrinologist, head of the diabetes, endocrinology and metabolism section of #KKB @RUBMedizin. Views are my own.
Joined Nov 2022
Neue Leitlinie zum Allan-Herndon-Dudley-Syndrom https://idw-online.de/de/news874122
In diabetes-certified hospitals, patients with #diabetes mellitus are faced with a significantly lower fatality. Specialised, highly qualified endocrine departments have to be preserved.
https://doi.org/10.3389/frhs.2026.1782882
https://pubmed.ncbi.nlm.nih.gov/42255026/
https://www.livivo.de/doc/M42255026
In diabetes-zertifizierten Krankenhäusern ist die Letalität bei Menschen mit #Diabetes mellitus hochsignifikant geringer. Spezialisierte, hochqualifizierte endokrinologische Einrichtungen müssen erhalten bleiben.
https://doi.org/10.3389/frhs.2026.1782882
https://pubmed.ncbi.nlm.nih.gov/42255026/
https://www.livivo.de/doc/M42255026
#MCT8 deficiency or #Allan_Herndon_Dudley syndrome is a rare disorder of #thyroid hormone transport, leading to severe neurodevelopmental delay. See our newest paper for monitoring recommendations.
https://pubmed.ncbi.nlm.nih.gov/41926547/
https://doi.org/10.1159/000551857
https://www.livivo.de/doc/M41926547
Wiley sent us a note that our paper defining the static disposition index #SPINA-DI is among the top-viewed articles of the Journal of Diabetes.
https://pubmed.ncbi.nlm.nih.gov/38169110/
https://doi.org/10.1111/1753-0407.13525
https://www.livivo.de/doc/M38169110
Ich weiß ja nicht, wer mich vorgeschlagen hat, aber ich bin ab sofort im (ursprünglich 1925 begründeten) Kürschnerschen Deutschen Gelehrtenkalender aufgeführt. Nicht allzu wichtig, aber ganz nett 😅. Ob man aber für die 4 Bände über 1000 € ausgeben möchte...?
https://www.degruyterbrill.com/document/isbn/9783111635460/html
Die politischen Rahmenbedingungen der präventiven Medizin sind in Deutschland unzureichend. Zusammen mit anderen Europäischen Ländern ist Deutschland Schlusslicht in der #Prävention. Das führt dazu, dass die Kosten hoch sind, aber die Lebenserwartung niedrig.
https://blog.endokrinologie.net/politische-rahmenbedingungen-der-praeventiven-medizin-6001/
Mathematical modelling, computer #simulation, and machine learning upgrade #endocrinology. Applying principles of #biocybernetics and #biophysics, they enjoy growing interest and deliver novel methods for research, diagnosis, and therapy.
https://pubmed.ncbi.nlm.nih.gov/41852474/
https://doi.org/10.3389/fendo.2026.1806508
#MCT8 Deficiency, or Allan-Herndon-Dudley syndrome, is a rare severe disorder of #thyroid hormone transport. In our newest paper, we review the state of the art on pathophysiology, diagnosis & treatment.
https://pubmed.ncbi.nlm.nih.gov/41508830/
https://doi.org/10.1210/clinem/dgaf707
https://www.livivo.de/doc/M41508830
Systems modelling explains: A #cybernetic theory of the molecular processes in #COVID-19 predicts oscillatory #inflammation and virus load in severe forms, which result from increased #TMPRSS2 expression.
Severe #COVID-19 is a life-threatening condition, sometimes requiring #ECMO (extracorporeal membrane oxygenation) therapy. In one of our studies, we found that oscillatory inflammation heralds a poor prognosis.
https://pubmed.ncbi.nlm.nih.gov/36991018/
#Endocrine feedback loops belong to the important foundations of life. However, consistent underlying rules are still lacking. Now, Moriya Raz, Uri Alon, and co-authors describe 5 classes of control circles.
https://www.livivo.de/doc/M41271754
https://pubmed.ncbi.nlm.nih.gov/41271754/
https://doi.org/10.1038/s41467-025-65924-4
#Takotsubo syndrome is a dangerous stress-related #heart disease. Since #T3 upregulates β-receptors, we assumed a link to #thyroid homeostasis. With machine learning, we identified interesting allostatic patterns.
https://www.livivo.de/doc/M33179374
https://pubmed.ncbi.nlm.nih.gov/33179374/
https://doi.org/10.1111/joim.13189
Therapy with #TRIAC, a non-classical #thyroid hormone, relieves peripheral #thyrotoxicosis and hypermetabolism in patients with resistance to thyroid hormone β (RTHβ).
https://pubmed.ncbi.nlm.nih.gov/41131705/
There is an ongoing debate in #endocrinology about whether to treat #hypothyroidism with L-T4 alone or a combination therapy with L-T4 and L-T3. But what about patients’ preferences? The majority would choose the combination therapy, as shown in a meta-analysis.
Einladung zur 3. Endokrinologischen Abendsprechstunde: Up-to-date Schilddrüse 2025
Von der #Kinderendokrinologie über #Schilddrüse und #Nebenschilddrüse bis zur Arbeit einer Selbsthilfegruppe in der #Endokrinologie
Patients with #hypothyroidism, even when treated with levothyroxine (L-T4), face increased risk of #dementia and #fatality. Fortunately, the risk can be lowered again by a combination therapy with L-T4 and L-T3, as shown by a recent study.
Freue mich über meine geheime Wahl in die #Leibniz-Sozietät der Wissenschaften zu Berlin.
Mehr Infos:
https://news.rub.de/leute/2025-07-30-auszeichnung-johannes-dietrich-neu-die-leibniz-sozietaet-aufgenommen
#Syndrome_T, i.e. persistent symptoms and reduced #QoL despite normal #TSH concentration, affects 10% of #hypothyroid patients on #levothyroxine. Careful, multimodal and personalised treatment can result in significantly improved outcomes.
- Sektion DES / Klinik
- http://www.endokrinologie.org
apl. Prof. Dr. med. Johannes Dietrich, endocrinologist, head of the diabetes, endocrinology and metabolism section of #KKB @RUBMedizin. Views are my own.
Joined Nov 2022
