#Inflammation plays a key role in the pathogenesis of #diabetes mellitus. In our newest paper, we show that treatment of #hidradenitis_suppurativa (#acne_inversa) may cause remission of diabetes. CN: medical images in full text. https://pubmed.ncbi.nlm.nih.gov/39106221/ https://doi.org/10.1111/ddg.15490
Die Grafen von #Neuburg-#Falkenstein waren ein bedeutendes Adelsgeschlecht der #Stauferzeit. Ihr Gebiet reichte von Oberbayern bis Südtirol und Niederösterreich. Ihre Stammburg #Unterfalkenstein wurde bei dem bayerischen #Hochwasser schwer beschädigt. #Klima
Sensorimotor #polyneuropathy may be common in treated autoimmune thyroiditis, but, unlike in other causes of #neuropathy (e. g. #diabetes), it has a unique pattern in quantitative sensory testing (#QST) with low thresholds for mechanical and thermal pain.
Should we, therefore, classify #syndrome_T as a psychosomatic disease? This would be premature and probably wrong. We found signs of sensorimotor and autonomic #neuropathy that depend on autoimmunity and #thyroid's secretory capacity (#SPINA_GT).
Our newest paper provides new insights into the conundrum of #syndrome_T / #sorshot. #Anxiety and #depression are significantly more common in autoimmune #thyroiditis compared to healthy controls.
Stellenausschreibung für Medizinische Fachangestellte in der Sektion #Diabetologie, #Endokrinologie und #Stoffwechsel am KKB / UK RUB @RUBMedizin.
Wir freuen und auf Ihre Bewerbung!
Die Deutsche Gesellschaft für #Kybernetik, Informations- und #Systemtheorie hat Peter K. Fleissner und mir den Heinz von Foerster-Preis verliehen.
Ich danke meinen Lehrer:innen und Kooperationspartner:innen, die meine Arbeit im Laufe der letzten 30 Jahre möglich gemacht haben.
Einladung zur Jahrestagung der Deutschen Gesellschaft für #Kybernetik im Rahmen der Jahrestagung der Leibniz-Sozietät in Berlin. Es erfolgt eine parallele Life-Übertragung online:
Sadly, John Midgley, a pioneer in #thyroid diagnostics and co-author of multiple papers by our group, passed away. Read Rudolf Hoermann's obituary at The Guardian:
https://www.theguardian.com/society/2024/apr/02/john-midgley-obituary
#SPINA_GT, #SPINA_GD and Jostel's TSH index (#JTI or #TSHI) are predictors of survival in patients with #Takotsubo syndrome (#stress #cardiomyopathy), as recently demonstrated in the international GEIST registry.
https://pubmed.ncbi.nlm.nih.gov/38502972/
https://doi.org/10.1016/j.ebiom.2024.105063
Our newest paper has been published. Based on machine learning with k-medoids #clustering we identified three different signatures of #thyroid #homeostasis that predict the prognosis of patients with #Takotsubo syndrome.
https://pubmed.ncbi.nlm.nih.gov/38502972/
https://doi.org/10.1016/j.ebiom.2024.105063
Therefore, the non-increased and, in many cases, even reduced beta cell function in metabolic syndrome may not mirror an "either-or" question but be part of continuous evolution. It may be a source of prediabetes and diabetes but also prevent insulinoma.
The answer to this question may be in glucose toxicity leading to a biphasic response, thereby preventing neoplastic effects of dynamical compensation by mutant takeover.
Simulation des Modells des #Insulin-#Glukose-#Regelkreises nach Bolie auf einem #Analogrechner (THE ANALOG THING)
Simulating Bolie's model of insulin-glucose homeostasis with an analog computer (THE ANALOG THING) #theanalogthing
Howard Page Clark, author of many books on programming with #Pascal, #ObjectPascal and the #Lazarus_IDE passed away. R. I. P. https://www.blaisepascalmagazine.eu
The Apple Macintosh has turned 40. Originally, it was a #Pascal machine, and #ObjectPascal has been developed to evolve its revolutionary operating system.
A novel method for early detection and #endotyping of #Diabetes mellitus relies on software written in #ObjectPascal.
Today, this innovative approach is covered by all major press agencies and news channels all over the globe.
apl. Prof. Dr. med. Johannes Dietrich, endocrinologist, head of the diabetes, endocrinology and metabolism section of #KKB @RUBMedizin. Views are my own.