Johannes W. Dietrich @drjwdietrich@qoto.org
- Sektion DES / Klinik
- http://www.endokrinologie.org
apl. Prof. Dr. med. Johannes Dietrich, endocrinologist, head of the diabetes, endocrinology and metabolism section of #KKB @RUBMedizin. Views are my own.
Joined Nov 2022
Weltweit und gleichzeitig radikalisieren sich Teile der Bevölkerung und driften nach rechts. Was ist die Ursache?
Neben maschineller Probaganda könnte auch der negative #Flynn-Effekt eine Rolle spielen, eine Intelligenzabnahme durch endokrine #Disruptoren.
https://blog.endokrinologie.net/intelligenzabnahme-flynn-effekt-4157/
Johannes W. Dietrich
boosted
Growing evidence supports a role of sensorimotor and autonomic #neuropathy in #syndrome_T or #SORSHOT, i.e. reduced quality of life in treated #hypothyroidism. #SPINA_GT and #SPINA_GD predict nerve function and depression.
Johannes W. Dietrich
boosted
Again, a study showed a strong influence of endocrine disruptors on #thyroid homeostasis. Exposure to butylparaben significantly reduces #SPINA-GD, whereas ethylparaben slightly increases #SPINA_GT in pregnancy.
About 10% of hypothyroid patients have reduced quality of life despite normal TSH concentration under therapy with levothyroxine (L-T4). A new randomised, double-blind trial demonstrated better QoL under L-T4 + L-T3 compared to L-T4 alone.
Teilnehmer:innen gesucht! Klinische Studie zur Verbesserung der #Insulintherapie bei #Diabetes mellitus Typ 1.
https://www.klinikum-bochum.de/fachbereiche/innere-medizin/diabetologie/insulin-studie.html
Digitale Zwillinge in der Endokrinologie: Der Weg zu einer prädiktiven und personalisierten Medizin. 🧪🩺
https://blog.endokrinologie.net/digitale-zwillinge-in-der-endokrinologie-5717/
Hintergrundartikel zum Thema in diabetologie-online:
#Smartwatches mit nichtinvasiver #Glukosemessung, ohne Stich, zuverlässig und günstig? Zu schön, um wahr zu sein! Untersuchungen des Instituts für #Diabetestechnologie in Ulm legen den Betrug offen. Selbst auf einer Banane wird ein #Blutzucker "gemessen". 🩺🧪
https://www.ifdt-ulm.de/fileadmin/website/Video_Content/Smartwatches_deutsch2.mp4
Johannes W. Dietrich
boosted
Endocrine disruptors have a strong effect on the peripheral #thyroid hormone metabolism. A recent study showed a nonlinear dose-response relationship between #PFAS and step-up deiodinase activity (#SPINA_GD).
https://pubmed.ncbi.nlm.nih.gov/39556482/
https://doi.org/10.1210/clinem/dgae798
Assessing diagnostic tools in #endocrinology with computer simulations https://link.medium.com/qDCugbiYZMb
Einladung zur 2. Endokrinologischen Abendsprechstunde "Up-to-date Schilddrüse 2024" am 25. September 2024.
#Schilddrüse #Nebenschilddrüse #Hypothyreose #Schilddrüsenchirurgie #Syndrom_T #SORSHOT
http://www.endokrinologie.org/resources/flyer-up-to-date-schilddruse-2024.pdf
#Metformin is a useful antidiabetic substance, but also an endocrine disruptor. A recent study shows that it reduces the set point of #thyroid homeostasis, but this effect is mitigated by #vitamin_D deficiency.
https://pubmed.ncbi.nlm.nih.gov/39204438/
https://doi.org/10.3390/pharmaceutics16081093
Which programming language is fit for high-performance computer simulations in biomedical #cybernetics? We found that #Free_Pascal generates faster code than S/R and #Python. Interestingly, Object #Pascal even outperforms #Swift and C++.
https://doi.org/10.14201/adcaij.31762
https://revistas.usal.es/cinco/index.php/2255-2863/article/view/31762
Both sensorimotor and autonomic #neuropathy may be common in #hypothyroidism, despite treatment.
#Inflammation plays a key role in the pathogenesis of #diabetes mellitus. In our newest paper, we show that treatment of #hidradenitis_suppurativa (#acne_inversa) may cause remission of diabetes. CN: medical images in full text. https://pubmed.ncbi.nlm.nih.gov/39106221/ https://doi.org/10.1111/ddg.15490
Die Grafen von #Neuburg-#Falkenstein waren ein bedeutendes Adelsgeschlecht der #Stauferzeit. Ihr Gebiet reichte von Oberbayern bis Südtirol und Niederösterreich. Ihre Stammburg #Unterfalkenstein wurde bei dem bayerischen #Hochwasser schwer beschädigt. #Klima
Sensorimotor #polyneuropathy may be common in treated autoimmune thyroiditis, but, unlike in other causes of #neuropathy (e. g. #diabetes), it has a unique pattern in quantitative sensory testing (#QST) with low thresholds for mechanical and thermal pain.
Should we, therefore, classify #syndrome_T as a psychosomatic disease? This would be premature and probably wrong. We found signs of sensorimotor and autonomic #neuropathy that depend on autoimmunity and #thyroid's secretory capacity (#SPINA_GT).
Our newest paper provides new insights into the conundrum of #syndrome_T / #sorshot. #Anxiety and #depression are significantly more common in autoimmune #thyroiditis compared to healthy controls.
- Sektion DES / Klinik
- http://www.endokrinologie.org
apl. Prof. Dr. med. Johannes Dietrich, endocrinologist, head of the diabetes, endocrinology and metabolism section of #KKB @RUBMedizin. Views are my own.
Joined Nov 2022
