Nicola Romanò @nicolaromano@qoto.org

Interesting, interesting!

'Our findings suggest that current genomic language models (gLMs) do not offer substantial advantages over conventional machine learning approaches that use one-hot encoded sequences. This work highlights a major limitation with current gLMs, raising potential issues in conventional pre-training strategies for the non-coding genome.'

https://www.biorxiv.org/content/10.1101/2024.02.29.582810v1

Postdoc position! We're a new research group at @IJMonod, Paris, interested in the cellular secretory landscape and its re-organisation during fibrosis.
Join us, and play a central role in shaping our vision in the coming years!
DM/email for questions
https://emploi.cnrs.fr/Offres/CDD/UMR7592-ISHRAO-003/Default.aspx?lang=EN

Gelman: "a lot of studies just shouldn't be done". too much noise, too poor an experimental design.

#preregistration

Researchers need to start simulating what data they are expecting to collect before they collect it.

My only comment on Gemini is that y'all take everything seriously when it offends white people when we've been yelling about issues for how long and when has a product ever been pulled and when has there ever been this type of shock and media attention?

It's such a pleasure when I get to ask a former PhD student for help on a current project—because it's an area that she knows better than I do.
In other words, I succeeded when she was my student.

The CEO of Exxon just said "we've waited too long" to tackle climate change. He blames "society" and "activists" from keeping Exxon from working on this.

Yes, Exxon. Yes, Exxon. Yes, Exxon: the corporation that for decades has been spending millions to slow progress on climate change, despite its own research showing the problem was urgent.

He said:

"We've waited too long to open the aperture on the solution sets in terms of what we need, as a society, to start reducing emissions.... Frankly, society, and the activist — the dominant voice in this discussion — has tried to exclude the industry that has the most capacity and the highest potential for helping with some of the technologies."

What the fuck is this — some sort of dark and twisted joke?

The interview is here:

https://web.archive.org/web/20240228015207/https://fortune.com/2024/02/27/exxon-ceo-darren-woods-interview-pay-the-price-for-net-zero/

https://www.salon.com/2024/02/29/exxon-ceo-to-world-climate-isnt-our-fault-now-pay-the-price/

Happy Birthday, R!

#rstats

Apparently #Clarivate's Web of Science, one of the major proprietary indexes that employers use to determine whether papers in a journal can be considered in tenure & promotion decisions, denied @joss 's request to be indexed without even telling us. This is not the first time JOSS has been rejected

I checked their "objective review criteria" and JOSS easily passes all the qualifications.

Speaking strictly as my own opinion, not in my role as a JOSS editor or reviewer, but as a matter of fact these indexers are a fucking racket.

https://github.com/openjournals/joss/issues/1283

Registration for posit::conf(2024) is now open: https://posit.co/conference/. It's going to be in Seattle, Aug 12-14, and we've tried really hard to make it more affordable this year, so I hope I can you see there in person! (We'll also have a virtual option; more on that soon)

if you remember using a cracked copy of nero to burn other cracked software onto cd, remember to do your gentle back stretches today

@nicolaromano These are great points. The difference is that sold engines were marketed as user driven tools, while LLMs as marketed to hype driven fools.