@rastinza @chemistry there is so much interesting work going on in protein design and engineering. It's fascinating to watch!
@GustavinoBevilacqua Ah, me lo immaginavo più piccolino. Beh, una buona scusa per bersi una birra, che certamente sarà sufficiente per rilassarsi durante le 6 ore!
@L_howes @chemistry
That's my favorite way to design proteins, just get around the table with a bunch of friends and build up the lego!
Since you talk about biological validation, I was recently in a lecture held by a Swiss guy (I don't have my notes with me right now).
His group was designing new proteins with genetic algorithms, but the cool part was that the genetic algorithm was a physical and biological one.
They would place a gene encoding a protein inside bacteria, induce random mutations and through microfluidics separate the cells which contained a good protein (they were evaluating the catalytic effects on some reaction). Then they would sequence all the good ones. And reintroduce them in the cycle.
This is quite cool, works and its rapid as well as I think they were processing some thousands proteins per second if I'm not mistaken.
@GustavinoBevilacqua Quanto devi stamparla grande perché la scritta esca scritta davvero?
In alternativa: quanto è piccola la punta più piccola che hai e quante ore sei disposto ad aspettare per ogni pezzo?
Il foro sulla punta secondo me è meglio farlo a mano che così sembra molto a rischio collasso.
@ralf As long as you believe that science is one objective thing and that observed things can't be subjective; you're absolutely right.
@ralf As long as you're not the scientist.
#todo Use LLMs as a review tool to see if you actually understood a topic.
Start writing about it and try to explain it to them, correct any error the incur into.
@FMarquardtGroup So, I took a look at a couple papers. The research at a first glance seems legit and moderately novel; it's experimental work.
Definitely he was not doing the experiments, I just skimmed through a paper in which the experimental part clearly took at the very least one month.
He may have taken part in the revision of the article, if you look at the articles he published it's immediately clear that he has a bunch of different authors in all the articles and those are almost never the same, while you would generally expect one running a research group to publish papers more or less with the same people.
Something is quite shady, I guess he's offering to edit articles to smaller researcher in order to place his name there and increase the rating of the publication.
Wow: "The chemist admitted that since December, he has been using the artificial intelligence program ChatGPT to “polish” his texts. “These months have been quite productive, because there are articles that used to require two or three days and now I do them in one day,” he said. "
-- from Le Pais: https://english.elpais.com/science-tech/2023-04-02/one-of-the-worlds-most-cited-scientists-rafael-luque-suspended-without-pay-for-13-years.html
Is it normal in chemistry to publish on average one paper every 37 hours?
@FMarquardtGroup In 37 hours you're lucky enough if you're able to run a reaction; and that's without accounting for deciding what to do, planning it, and cleaning up afterwards. Moreover, in most cases the reaction just won't work and you'll have to try again.
No, publishing an article every 37 hours is nowhere near believable.
I believe someone who is very knowledgeable of a topic could just keep writing articles about that topic, however I don't see what significant new idea he could come up from one day to the other. All articles may be well written and sensed, but pretty much containing the same information.
That said, I'll read one of his articles and come back with a more informed opinion.
@elduvelle @coolbutuseless I used visual software for a long time, then I realised that for normal operation it's just faster to go through the commands and that for advanced stuff it generally just works better on the cli
@resistenza_non_binaria With short term I mean 20-30 years.
@cyrilpedia Well, when you select one of the best Italian wine varieties it's difficult to get something bad.
Portugal has amazing wine, but indeed you can find very good wines in plenty other places.
I opened LinkedIn today and I was shocked by a lot of Italians writing posts, either in Italian or in terrible English, condemning the Italian Privacy Institution for having sanctioned OpenAI because they were infringing the Italian privacy laws.
This is absurd, we have a government that courageously confronts a huge company telling them to fuck off unless they abide by our laws and people condemn it.
I'm more and more convinced there is no real way to improve Italian society in the short term.
@InayaShujaat @Tutanota @jackyan Sad to hear that. Unfortunately, using a different communication media is not enough to change peoples mind.
@hschmale @Tutanota I don't think you'll find what you're searching for here.
Don't get me wrong, there are some people doing that, but I feel this is not a good place for such things and the vast majority of users don't use this social that way.
A better place to find such things are blogs.
Here I appreciate the community building process and the societal development. It's not people following other people but rather creating meaningful relationships with other users, getting to know them and discovering what springs from common interests.
Generally, I interact with a few groups of people whom I share something with and only rarely I get to write things for the general public.
I do sometimes write extensive analysis on some topics, but these are generally in a discussion with somebody. As an example: I am a chemist and some time ago there was a discussion about the methodologies to deal with tear gas; so I helped them out by performing a literature review on the topic and providing them with extensive information about the different types of tear gases and possible remedies.
You give to other people and get from them.
I try to keep the amount of people I follow small, as that helps me to have a cleaner and more explorable home timeline.
Italian, MSc in chemistry specialized in cheminformatics and QSAR.
I'm interested in cooking and building stuff.
I love traveling, I lived in India, China, Slovenia, Poland and Spain.
Currently working in Spain in the field of genomics; and doing a PhD in Drug Development using Quantum Mechanics and Artificial Intelligence.
Don't take what I say as an insult, I have no bad intentions and I'm open to talk about it.
Don't star my toots, I find that often useless: if you liked it send a reply.
Consider boosting the toots, it's the only real way in which stuff is propagated through mastodon.