Show newer
Hao Yin boosted
Development

Focal adhesions help endothelial cells get in line

A Research Highlight showcasing new work from Tevin Chau, Anne Lagendijk and colleagues
journals.biologists.com/dev/ar

We interviewed the authors of the paper, Tevin Chau and Anne Lagendijk, for our 'The people behind the papers' series.
journals.biologists.com/dev/ar

Read the full #OpenAccess Research Article, ‘Dynamically regulated focal adhesions coordinate endothelial cell remodelling in developing vasculature’ here: journals.biologists.com/dev/ar

#devbio

0
Hao Yin boosted
Julie-Françoise Garand

Smoking and progressive retinal nerve fibre layer thinning in glaucoma
bjo.bmj.com/content/early/2022

0
Hao Yin

In , -enriched plasma cell-free DNA methylation correlated with ascending aortic in regions of elevated (4D flow MRI), but Not aortic diameter

An interesting method to identify tissue-enriched DNA methylation in this paper

Roadmap Epigenomics
BluePrint Epigenome
Metilene
bioinf.uni-leipzig.de/Software

24 candidate aorta-enriched differentially methylated regions
4 used in this study

Dr. Steven Greenway lab Clin Epigenetics 2021
clinicalepigeneticsjournal.bio

0
Hao Yin boosted
Theory of Living Matter Group

RT @VeniceEvoDevo
Venice Evo Devo Summer School 2023: The Future of Evo-Devo

August 21-25, 2023
Centro Cultural Don Orione Artigianelli, Venice

Registration at:
meetings.embo.org/event/23-evo

Check out our amazing line-up!

Deadline is March 31, 2023.

@EMBOevents
#EMBOevoDevoSystems
#VeniceEvoDevo

0
Hao Yin

Splendid by Kristy Red-Horse lab

Endocardial Origin of Coronary +Arteriogenesis

A fascinating BMP2+ transitioning e17.5 coronary EC population

How EC & nonvascular BMPs coordinate heart 😆

Exogenous BMP2 synergizes with VEGF-A⏫endocardial-derived Angiogenic sprouting from e10.5🫀ventricle explants

LDN193189, BMPR inhibitor,⏬endocardial contribution to coronary vascularization

AAV9-cTnt-Bmp2⏫endocardial-derived angiogenesis in neonatal 🤠

Dev Cell 2022 @kristyredhorse
cell.com/developmental-cell/fu

0
Hao Yin boosted
Marie Kmita

'Mechanical forces across compartments coordinate cell shape and fate transitions to generate tissue architecture'
#DevBio
biorxiv.org/content/10.1101/20

0
Hao Yin

ApoE KO🐶♂️normal diet 18 mo
Multi-arterial ->
MI/Stroke/Gangrene

scRNAseq athero-prone vs -resistant arteries
+ - LTBP1+ myofibroblast transition in atherogenesis

Dr. X. Wang, YB Zhang, X Ji labs Aging Dis 2022
aginganddisease.org/EN/10.1433

0
Hao Yin boosted
Mathis Riehle

Lecturer in Molecular Genetics (Learning, Teaching & Scholarship) @UofGSMB@twitter.com @UofGMVLS@twitter.com open for applications, closing date 30 January 2023. Full-time post, Grade 7, for 2 years.
Great colleagues superb students, great University!
my.corehr.com/pls/uogrecruit/e

0
Hao Yin boosted
Patrick MacDonald

From our colleagues in Copenhagen. FKBP2 and it’s role in insulin processing.

biorxiv.org/content/10.1101/20

0
Hao Yin boosted
Theory of Living Matter Group

RT @quantumjot
🚨JOB ALERT: We have multiple new postdoc positions at @turinginst to develop #ComputerVision and #MachineLearning methods for #bioimageanalysis and more. Join an awesome team and explore the use of #AI for science.🚀Please RT.

DEADLINE: 5th Jan 2023

cezanneondemand.intervieweb.it

0
Hao Yin

control of transport links microvascular dysfunction with

EC Sirt6->
⏬H3K9ac PPARγ promoter
⏬CD36,FABP4/5
⏬🐭 Heart Lipid

Dr. Zheng Gen Jin lab Circ Res 2022
ahajournals.org/doi/10.1161/CI

0
Hao Yin

in🐭 1/2

AMPK or Sestrin as potential autophagic regulators

Dr. Mattia Scalabrin & Scott Bowen lab AJP CellPhys 2022
journals.physiology.org/doi/ab

Which tissue does autophagy occur in (likely based on Western blot)? And its functional impacts?

in🐭 2/2

Evidence on autophagy induced by ischemia/#Hypoxia in , and its stimulatory effects on

Dr. Joo-Won Jeong lab Cell Death Dis 2020
nature.com/articles/s41419-020

0
Hao Yin boosted
Theory of Living Matter Group

RT @BardinLab
Come join us for an exciting meeting on Growth, Regeneration, and Aging in Roscoff, France, May 22-26, 2023!
insb.cnrs.fr/fr/growth-and-reg

0
Hao Yin

ICAM1-hi form Hotspots for (Paracellular)

Blunting ICAM1 heterogeneity
⏬TEM hotspots
⏫TEM-associated endothelial Permeability

Dr. Jaap van Buul lab @emboreports 2022 @joachimgoedhart @VanBuul_lab
embopress.org/doi/full/10.1525

Impossible to make a better presentation on this great paper than first-author Max Grönloh @GronlohMax 👇

Also don't miss the informative Discussion session synthesizing the signaling networks of leukocyte TEM

Congratulations!👏👏👏

twitter.com/GronlohMax/status/

0
Hao Yin

Apold1, a -enriched gene, in pathological
⏬Reperfusion (3 dpi🤓)-> An arteriogenic defect?
⏫border zone vascularization at day 21 but not day 7
Tumor ⏫Nonproductive angiogenesis-> more non-perfusable endothelial channels

Apold1 KO⏬EC Proliferation-How😁

@bohaceklab@nerdculture.de & Katrien de Bock bioRxiv 2022
biorxiv.org/content/10.1101/20

Also very interesting, Apold1 KO->⏫KLF2 & KLF4 in EC

Apold1 is recently identified as an ascending aortic EC-enriched gene (vs descending aorta/carotid artery)
Dr. Thomas Quertermous lab bioXRiv 2022
biorxiv.org/content/10.1101/20

Are Apold1 KO mice ready for /#Aneurysm?

0
Hao Yin

Venous as origin in🐭

Blocking VEGFA (Bevacizumab 7 dpi)
⏬Aberrant angiogenesis
⏫Myelination+neuromotor
BUT w/o altering Immune cell infiltration or Endothelial Barrier (IgG)😎
Dr. Dritan Agalliu lab bioXRiv 2022
biorxiv.org/content/10.1101/20

0
Hao Yin boosted
Martinho lab

Quick question for the Drosophila aficionados :) have ever come across with a suppressor of the dominant mutation IF? I have a IF/Cyo stock and everything is ok exempt that the IF eye ia gone :) i gave seen Tb disappear from a TM6b (where Hu is still around), but never had IF vanishing into oblivion… just curious….

1+
Hao Yin

The amoeboid state as part of the epithelial-to-mesenchymal transition programme

Linking cell Shape control, Cytokine signaling with Cancer Stemness & Malignancy🤠

Dr. Victoria Sanz-Moreno lab @TrendsCellBio 2022
cell.com/trends/cell-biology/f

0
Hao Yin boosted
Joachim Goedhart

I add three more protocols to my book on data visualization in R/ggplot2 for wet lab scientists.
Protocol 13 explains how to plot multiple plots side-by-side.
Find all protocols here: joachimgoedhart.github.io/Data

1
Hao Yin

in🐭👹


-Use target cell membrane to encapsulate🍃NanoThylakoid Units & evade cross-species elimination
-Supply ATP+NADPH for days in recipient cells

Intra-articular injection🐭causes no overt 🥸

Metabolic profiles of Chondrocytes+Thylakoids🤠

Dr. Ruikang Tang, Shunwu Fan & Xianfeng Lin labs Nature 2022
nature.com/articles/s41586-022

Photosynthetic medicine for

A lay summary👇
Plant-cell machinery for making metabolites transferred to mammalian cells
nature.com/articles/d41586-022

0
Show older
Qoto Mastodon

QOTO: Question Others to Teach Ourselves
An inclusive, Academic Freedom, instance
All cultures welcome.
Hate speech and harassment strictly forbidden.

Trending now

Resources

Developers

What is Mastodon?

qoto.org

More…

v3.5.19-qoto · Privacy policy