Today, a wonderful mutation methodology was presented to me in a conference, this was used to generate new proteins to act as enzymes for specific reactions.
They used microfluidics, which already by itself places them in the cool category.
Basically they made up this system in which they have bacterias producing an enzyme, through microfluidics they push a single cell inside a bubble with the reaction substrate and some lysing agent.
The enzyme comes out and the reaction proceeds producing a fluorescent compound, the fluorescence is measured to assess the catalytic performance and based on that, droplets are separated thanks to microfluidics magic.
The good ones go through another stage in which the dna is sequenced to determine what the protein is and random mutations are induced and inserted in other bacterias that are then sent a the beginning of the process.
The whole thing is automatic and they process 1000 proteins per second.
That's crazy, sounded like magic to me.
Cool stuff, I have to insert some microfluidics somewhere in my projects. Microfluidics is better than AI. I have to learn microfluidics now.
Guess who's investing the most money in fossil fuels?
Source: https://www.iea.org/data-and-statistics/data-product/world-energy-investment-2022-datafile
How the Dunning-Kruger effect is just sugar for the ego (but mathematically wrong):
https://economicsfromthetopdown.com/2022/04/08/the-dunning-kruger-effect-is-autocorrelation/
Bolsonaro cerca casa a Verona. Se per il tentato golpe per lui si mettesse male potrebbe sempre venire in Veneto e chiedere la cittadinanza italiana in quanto figlio di emigrati padovani..
https://www.ilgazzettino.it/nordest/padova/bolsonaro_cerca_casa_italia_vento_verona_cittadinanza_fuga_dal_brasile-7208299.html
Every once in a while I get into conversations here on Mastodon that don't end up well.
I try to improve myself, could you please take a look at this one and tell me where I've been so rude and aggressive and how I could have handled it better? I realise my final answer could be interpreted aggressive, but I do not see the problem in everything else I have written.
I went through it a few times and if anything it appears to me that he was a bit quick to conclude and disrespectful, but just to a very small extent which does not cause problems and which is to be expected when you start talking with someone you don't know.
Please, refrain from interacting with the guy unless you knew him before: he blocked me and directing people towards talking to him would be a bad practice, I just want some insight on my behaviour.
@antanicus A me sembra una figata che d'ora in poi il produttore della mia auto potrà estorcermi denaro in cambio di piccole funzionalità aggiunte al mio veicolo e che in questo modo possa guadagnare più soldi rispetto ai metodi tradizionali.
Mi ricorda quell'affermazione, mi pare fosse di Primo Levi "Quando i tedeschi trovarono un modo per sfamarci con la merda, fui molto felice perché in questo modo avrebbero potuto utilizzare tutte le patate che prima davano a noi per sfamare i soldati sul fronte".
The idea that bad people having a voice on social media causes other people to become bad people (often the argument as to why we must defederate from bad servers) is equivalent to:
Thinking violent video games cause people to become violent.
Thinking explicit song lyrics cause people to become criminals
Allowing people to be openly homosexual will cause others to become homosexual
Banning books
Everyday we have freshly sprouted legumes. We love it because we can carry them dried and rehydrate them months later. Today's mixtape is lentils, radish and fenugreek.
But is this correlation or causation? It seems almost like Black folk are suggesting that police activity *causes* more murders to happen?
We can test this (and we have!) by seeing what happens if you go into a neighborhood with a lot of murders, and get police to stop brutalizing innocent Black people, and focus only on stopping murders.
Result: You can end a murder wave in a city by getting cops to focus on murders instead of being evil.
Operation Ceasefire works.
https://www.npr.org/2011/11/01/141803766/interrupting-violence-with-the-message-dont-shoot
The carbon footprint of NFTs on Ethereum wasn’t looking great before The Merge, but it was nothing compared to on-chain Bitcoin NFTs
Yesterday Bitcoin mining company Luxor mined the largest block ever, containing almost exactly 4MB of data. Only 63 transactions could fit into the block, as the NFT used up the rest of the available space
The carbon footprint: ~888 metric tons of CO2, equivalent to the per passenger carbon footprint of taking a flight from New York to Tokyo and back - 466 times
In this quest for independence from centralized social media, I'm wondering...does anyone still use RSS?
For any of you who do, what is the experience of using RSS in 2023? Are there any RSS apps that are pleasant to use? Sites (other than big content publishers) that publish a feed?
(Please share for visibility if you have followers who might have experience to share.)
A couple very rough estimates retrieved quickly in 5 minutes from official Elsevier data.
RELX, the company which owns Elsevier has a capitalization of 56£ billion. Elsevier publishes around 600.000 articles per year and the average price per submission is 2350£ (simple average over submission price in every journal, not counting amount of articles published.)
The average subscription price for each journal is 3524£, I'll assume 600.000 subscription just to have a number.
This means that research institutes and universities overall would pay around 3.5£ billion to Elsevier every year. By saving that money, we could collectively buy Elsevier in less than 10 years.
Maybe we should set up an association, every time you pay money to Elsevier you'd have to make a donation to such association with the objective of buying the majority of RELX.
This would be an economically sound decision.
Italian, MSc in chemistry specialized in cheminformatics and QSAR.
I'm interested in cooking and building stuff.
I love traveling, I lived in India, China, Slovenia, Poland and Spain.
Currently working in Spain in the field of genomics; and doing a PhD in Drug Development using Quantum Mechanics and Artificial Intelligence.
Don't take what I say as an insult, I have no bad intentions and I'm open to talk about it.
Don't star my toots, I find that often useless: if you liked it send a reply.
Consider boosting the toots, it's the only real way in which stuff is propagated through mastodon.