Paul Sutton @zleap@qoto.org

In a first for the #genetic toolset known as #CRISPR, a recently discovered #protein has been found to act as a kind of multipurpose self-destruct system for #bacteria, capable of degrading single-stranded #RNA, single-stranded DNA and double-stranded DNA.
#Biology #sflorg
https://www.sflorg.com/2023/01/bio01042303.html

If you’re outraged about Adobe sending your pictures off their servers (you should be), please know other vendors do this too. That horse has already bolted.

Eg Microsoft Edge automatically sends your key presses in Edge to MS - enabled by default https://winbuzzer.com/2022/09/19/microsoft-editor-in-edge-sending-personla-info-to-microsoft-could-be-putting-users-at-risk-xcxwbn/

Microsoft Office 365 sends every photo and screenshot you add in Word, PowerPoint etc (including in emails) to Microsoft 365 Intelligent Services without prompt https://support.microsoft.com/en-us/office/everything-you-need-to-know-to-write-effective-alt-text-df98f884-ca3d-456c-807b-1a1fa82f5dc2

What fresh hell is this? Adobe has opted me in to letting them train their algorithms on my photos? That’s the end of me using their cloud storage for anything, ever. #privacy #adobe #lightroom #LightroomMobile

#physics #weather Last time, extreme weather was caused by a 'dancing jet stream' Now, they are into 'straight'. This is the Wednesday dance. On the physics side, the Arctic headpond still builds up, and all the ocean plumes are low and flat. At least the polar vortex fairies are quiet.

imagine during that time Hitler was gaining power in Europe, while mathematicians and engineers (applied physicists) were developing the theoretical foundations of modern digital computers
you can take a peek on Alan Turing's 1936 paper from this link
https://www.cs.virginia.edu/~evans/greatworks/

those papers certainly are additional resource materials as i am also into basic applications of logic circuits
(self promotion ;) of course here i arrived at one of de Morgan's theorems! see table 3)
https://foxtrotpaparomeo.wordpress.com/2022/10/28/02052022-updatesbasic-zener-diode-discrete-gate-network-applied-automation-in-battery-charger/

'Attempts to eradicate cancer cells expressing unique target proteins, such as antibody-drug conjugates (ADCs), T-cell engaging therapies, and radiopharmaceuticals have been successful in the clinic, but they are limited by the number of targets given the inability to target intracellular proteins.'

#preprint
https://www.biorxiv.org/content/10.1101/2023.01.01.522436v1

Data Structures Easy to Advanced Course - Full Tutorial from a Google Engineer
https://www.youtube.com/watch?v=RBSGKlAvoiM&t=14s

From customers to guardians: why the permanent record of scholarly publishing should be managed and made public by universities rather than private oligopolies: https://zenodo.org/record/6948200

Love your local library

(from @neilhimself Books of Magic)

Journalists: If you've installed Signal for secure chats with your sources, here's our guide to tightening it up and locking it down:

https://freedom.press/training/locking-down-signal/

Dear all companies everywhere: put a useful email address on your emails to customers. I'm so sick of "this email isn't monitored". You shouldn't be sending me emails I can't respond to, and if you do I'm not gonna order from you any more. That is all.

Time for a quick #introduction: I'm an academic working at the University of Southampton in the UK. I tend to write about #SpaceDebris & #SpaceSustainability, domains I have been researching for 20 years. I also provide monthly updates on conjunctions in orbit involving #Starlink and #OneWeb, something I will try to do here as well as on Twitter. Occasionally, I will write about my experiences as a #pwME in an effort to raise awareness of an overlooked & often invisible chronic illness

Turns out that Adobe is collecting all of its customers' pictures into a machine learning training set.

This is opt-out, not opt-in so if you use Lightroom, for example, it defaults to adding all of your photos to the set.

If these are unpublished pictures, work-in-progress, etc. they'll still be analysed as soon as they're synced.

I've been using Lightroom to sync photos from my Windows desktop to my iPad. Now I need to reconsider that.

It's #TriviaDay!

Put your Hubble knowledge to the test with our short Q&A videos.

Ready? Let's go: https://go.nasa.gov/3Zc2v4W
#Hubble

A group of Chinese researchers claims it can break 2048-bit RSA using a quantum-ish computer and it's worth reading Schneier's comments https://www.schneier.com/blog/archives/2023/01/breaking-rsa-with-a-quantum-computer.html

@zleap @catvalente what entirely is missing from this discussion is that tate is a symptom.

If you get #SSL_ERROR_NO_CYPHER_OVERLAP (Firefox) or #ERR_SSL_VERSION_OR_CIPHER_MISMATCH (Chromium) errors when calling https.createServer() in Node.js, you’ve got your options and listener order reversed in your method call. It should be options first, listener second.

(I’m actually working on generating certificate authorities/certificates so I was frantically searching the X.509 code for some obscure bug.)

My kingdom for parameter objects/named parameters.

#NodeJS #https #tls #ssl #error

UK artists! Your government just published a call for opinions on AI generated artwork, and your voice is needed!

They are affirming that under current law, artwork used to train AI without license or permission is most likely copyright infringement - but they're calling for the public's opinion on whether the law should be changed to make exceptions for use with AI.

You should probably tell them no! Email address is at the bottom of the page.

Please boost!

https://www.gov.uk/government/consultations/artificial-intelligence-and-intellectual-property-call-for-views/artificial-intelligence-call-for-views-copyright-and-related-rights

Essentially an account set up this way should be able to be considered by a server as “read only” - no “reply” button.

Also the idea of an activity pub “bulk” API in the Server-to-Server API would be good for upstreaming data on boosts back to the sending server.